II. Updates: December 2018
-
Hemorrhagic Shock (er, cv, bleed)
- Primary priority is the identification of Hemorrhage as shock cause, localizing Hemorrhage site, and rapidly stopping further bleeding
- Avoid overly aggressive crystaloid infusion, and aside from Traumatic Brain Injury, allow permissive Hypotension with SBP 80-100 mmHg
- Rapidly transfer to Trauma Center and operating room for definitive management for persistent compartment Hemorrhage
- Consider TXA (Tranexamic Acid) within first 3 hours of onset
-
Conduct Disorder (peds, psych, behavior)
- Lifetime Prevalence approaches 10% and diagnosis has remained virtually unchanged through DSM-4 and 5
- Diagnosis is based on characteristic behaviors within 4 categories: Aggression, Property Destruction, Lying or theft, rule violation
- Management focuses on non-pharmacologic measures and comorbidity management (esp. ADHD), although Risperidone may be used in refractory cases
- As many as 65% will develop Antisocial Personality disorder, and other risks include criminality, Substance Abuse and failure to complete school
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Healthcare of the Incarcerated Patient (prevent, Health Maintenance)
- At any one time in the U.S., 720,000 persons are incarcerated, roughly the population size of San Francisco
- Prisoners are at higher risk for nearly every medical and psychiatric condition, especially communicable disease and Substance Abuse
- Most Prisoners undergo an initial brief evaluation to confirm that they are fit for incarceration, and later undergo a more complete intake health evaluation
-
Crohn's Disease (gi, ibd)
- Consider Fecal Calprotectin as an initial test to rule-out Crohn's Disease, then confirm with endoscopy or CT or MRI enterography
- Biologic Agents are first-line management, with high efficacy, but with the risk associated with Immunosuppression
-
Human Sex Trafficking (prevent, abuse)
- Human Sex Trafficking is increasing in Incidence and acute care settings are a common contact point for trafficking victims
- Keep a high index of suspicion in teens and young adults who are accompanied by companions who dominate the encounter
- Use Medical Interpreters and interview patients alone
-
Dental Health (dental, exam)
- Dental Caries lead to Reversible Pulpitis, Irreversible Pulpitis and ultimately dental abscess or dental Cellulitis
- Periodontal Disease may progress from Gingivitis to Periodontitis
- Dental Trauma includes Tooth Fracture, Tooth Luxation and Tooth Avulsion
- Prevention includes reducing Xerostomia, fewer Simple Sugars, Tobacco Cessation, regular brushing and flossing, regular dental care
-
Diplopia (eye, sx)
- Monocular Diplopia persists regardless of whether the unaffected eye is open or closed. Monocular Diplopia is due to primary eye problems
- Binocular Diplopia resolves when one eye is closed and is caused by eye malalignment typically from a Cranial Nerve deficit
- Cranial Nerve 3 deficts (eye looks down and out, Mydriasis, Ptosis) should prompt emergent CT and CTA to exclude Posterior Communicating Artery aneurysm
-
Gonococcal Arthritis (id, rheum)
- Joint Pain in acute Gonorrhea may be due to Disseminated Gonorrhea dermatitis syndrome or to septic Monoarthritis
- Obtain Gonorrhea Cultures from all sources (blood, Rectum, pharynx, Urethra, Cervix) including Joint Aspiration
- Empiric initial management with Ceftriaxone and Azithromycin
-
Alcohol Withdrawal (psych, cd)
- Consider Ketamine 0.2 mg/kg/hour in Benzodiazepine refractory Alcohol Withdrawal
- Rabies Postexposure Prophylaxis (id, immunize)
-
Fall on Outstretched Hand (ortho, sx, hand)
- Consider Carpal Tunnel view if concern for Pisiform or hook of hamate Fracture, or Scaphoid tubercle Fracture
- Consider clenched fist view to evaluate for Scapholunate Dislocation
- Consider radial head-capitellum view to evaluate for Radial Head Fracture
- High Flow Nasal Oxygen (lung, procedure)
- Although it offers some NIPPV, a large part of its mechanism is in oxygenating the proportionately large airway dead space in young children
-
Transgender (prevent, HME)
- Train clinicians and staff on culturally sensitive terms and topics
- Be aware of hormonal therapy and surgical management of Transgender Persons and potential complications, monitoring
- Avoid attempting to convert person's Gender Identity to that of their birth sex is considered unethical
-
Influenza (id, virus)
- In adults, the classic triad is fever, cough and Pharyngitis with a 80-85% Test Sensitivity and 75-80% Test Specificity
- In children, the classic triad is present 60% of the time, and they have gastrointestinal symptoms in up to 30% of cases
-
Adolescent History (peds, exam)
- HEADSS Psychosocial Interview of teen patients broadly reviews important topics including drugs, sex and Suicidality
-
Orthotics (ortho, procedure)
- Updated Knee Braces, Ankle Braces, Wrist Splints
- Anatomy Images
- Five new images completed: sensory Dermatomes, Rule of 9s (adult and infant), Cardiomyopathy, wrist supinators and pronators
- Baloxavir Marboxil (id, pharm, virus)
- Xarelto (hemeonc, pharm)
-
Gardasil-9 (id, immunize, virus)
- As of 2018, Gardasil is approved for use in 27-45 year old women and men at risk
-
Raynaud's Phenomenon (rheum, cv)
- Avoid Vasoconstrictors and consider vasodilators (e.g. Norvasc, Nifedipine, or in refractory cases, Sildenafil)
-
Activated Charcoal (er, pharm, toxin)
- Expect to see it in toothpaste, mouthwash cleansers and oral supplements
- No evidence of benefit in consumer products and risks of prescribed medication malabsorption, Tooth Erosions, Constipation
-
Migraine Prophylaxis (neuro, Headache)
- Migraine Prophylaxis cost grows to $6900 for CGRP Antagonists with similar efficacy to their cheaper counterparts (e.g. TCA, Propranolol, topomax)
-
Biosimilars (id, pharm)
- Biosimilar agents are similar but not identical to their reference Biologic Agents (e.g. Nivestym is biosimilar to Neupogen)
III. Updates: November 2018
-
Hypertension in Children (cv, htn, peds)
- Hypertension diagnostic criteria in children have changed as of 2017 AAP guidelines
- Hypertension is underdiagnosed in children (only 26% are formally diagnosed)
- Essential Hypertension is the most common cause of Hypertension in Children (previously Secondary Hypertension was most common)
-
Urinary Retention (urology, sx, Bladder)
- Acute Urinary Retention is a urologic emergency, requiring immediate Bladder decompression with Urinary Catheterization (or Suprapubic Catheter)
- Acute Urinary Retention is often treated with indwelling catheter for 3-7 days, initiate Flomax, and follow-up urology for post-void residual
- On acute Urinary Retention, assess for Medication Causes of Urinary Retention, neurologic causes, post-void residual
-
Major Depression (psych, depression)
- Major DepressionPrevalence is as high as 8% (16 Million adults), and esp. in elderly and in Nursing Homes where depression Prevalence approaches 50%
- Yet, only 5% of the clinic population is screened for Major Depression
- Depression in women may present with Headaches, myalgias and gastrointestinal complaints
- Depression in men may present with anger, aggression, Substance Use Disorder and risky behavior
-
Knee Pain (ortho, Knee)
- Rapid onset of Knee Effusion after Trauma suggests internal knee derangement (e.g. meniscal tear, ACL or PCL Tear)
- Thessaly Test is more accurate for meniscal tear than McMurray Testing
- Knee MRI has limited indications in the acute setting, and mechanical symptoms are generally referred to rehabilitation first prior to MRI
-
Hyperemesis Gravidarum (ob, gi)
- Onset before 4 weeks and after 12 weeks should prompt consideration of other causes of Nausea and Vomiting in Pregnancy
- Primary treatments include non-pharmacologic measures, Vitamin B6, Doxylamine and Reglan
-
Urinary Tract Infection in Pregnancy (uro, ob)
- Bacteriuria is associated with Preterm Labor
-
Seizure (neuro, Seizure)
- Status Epilepticus is now defined as 5 minutes of continued Seizure (instead of the prior 30 min duration)
- First line management of Status Epilepticus is ABC Management, reversible cause treatment (e.g. Glucose), and Benzodiazepines
- Laboratory testing and imaging for a single Seizure has specific indications, and many will not require testing (beyond fingerstick Glucose)
-
Sickle Cell Anemia (hemeonc, Hemoglobin)
- Febrile Sickle Cell Anemia patients are management as Asplenic and Immunocompromised
- Treat vaso-occlusive crisis aggressively and rapidly and evaluate for other causes if pain pattern is not typical for patient
- Acute Chest Syndrome and Splenic Sequestration are medical emergencies
-
Low Back Pain in Pregnancy (ortho, ob)
- Symptomatic management includes Exercise, PT, Acupuncture, support devices, epidural Corticosteroids
- Exclude Placental Abruption, labor, Ureterolithiasis, Pyelonephritis
-
Type 2 Diabetes Mellitus in Children (endo, dm, peds)
- Type II Diabetes accounts for 1 in 3 diabetes diagnoses in children in the U.S.
- Type II Diabetes may present with Ketoacidosis as well as positive Glutamic Acid decarboxylase or islet Antigen-2 Antibody
- Screen diabetes in children age >10, if Overweight and at least 2 other risks (FHx, maternal Gestational Diabetes, high risk ethnicity, signs Insulin Resistance)
- Metformin and Insulin are the only FDA approved medications for Type 2 Diabetes in children
-
Cerumen Impaction (ent, ear)
- Avoid cotton tipped swabs, candling and olive oil drops
- Home Cerumen Softening Agents are as effective and safe as office removal techniques (as long as TM is intact)
-
Endotracheal Intubation (lung, procedure)
- Preventing aspiration is key
- Raise the head of bed and avoid excessive Positive Pressure Ventilation
- Consider Nasogastric Tube prior to intubation in Bowel Obstruction
- Have adequate suction (there are much better suction tips than Yankauer)
-
Push Dose Pressor (cv, pharm)
- In addition to Phenylephrine and Epinephrine, Norepinephrine can be used as a Push Dose Pressor without dilution at 0.5-1 cc (8-16 mcg)
-
Rectal Foreign Body (gi, Rectum)
- Patients with peritonitis should be consulted for emergent surgery
- Some rectal foreign bodies may be removed in the ED, with Procedural Sedation, speculum, and using fingers or swab sticks to manipulate the object out
-
Biologic Agents (id, pharm)
- These agents include monoclonal antibodies, and have numerous potential adverse effects
- Standardized naming conventions can help decipher these agents source, target and mechanism
-
Medications in Lactation (ob, pharm)
- Pumping and Dumping is not benign, especially in early pregnancy, as this risks discontinuation of Breast Feeding
- CT IV Contrast is compatible with Lactation and needs no pumping and dumping
- Ibuprofen is the preferred NSAID in Lactation
- All maternal Opioids sedate lactating infants, but especially avoid Demerol, Codeine, Oxycodone
-
Urinary Tract Infection (urology, id)
- Consider single dose Fosfomycin in the emergency department for noncompliant patients (but has a 58% cure rate compared with 70% for Nitrofurantoin)
- In children, when planning catheterization, consider Bedside Ultrasound first to confirm adequate urine to prevent dry catheterization (30% of cases)
- Drug Resistance in Pneumonia Score (lung, exam)
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Epidural Blood Patch (neuro, procedure)
- Performed by injecting 20-30 cc into a patient's epidural space and allowing it to spread and coagulate along the dura, plugging CSF Leaks
-
Severe Asymptomatic Hypertension (cv, htn)
- Most patients may follow-up with their primary providers for medication adjustments and additions
- Patients with systolic Blood Pressure >180, or >160/110 with comorbidities may benefit from initiation of Blood Pressure management in the ED
- No Labs are typically needed until follow-up (although consider Creatinine and Potassium if starting an ACE or ARB)
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Cardiac Risk Management (cv, prevent)
- Aspirin is out as primary prevention due to lower efficacy even with most risk factors and risk of GI Bleeding
- However Aspirin remains a critical part of secondary and tertiary prevention
- Benefit of Aspirin Use in Diabetes marginally outweighs the risk of GI Bleeding
- SGLT Inhibitor (endo, pharm, dm)
- SGLT Inhibitors are now associated with Fournier's Gangrene and Pancreatitis
- Endocarditis (cv, valve, id)
- Some patients with left sided endocarditis (mitral valve, aortic valve), may be considered for oral Antibiotics after initial first 2 weeks of IV Antibiotics
-
Corticosteroid Associated Osteoporosis (endo, pharm)
- Greatest effect on Bone Mineral Density with chronic Corticosteroids is in the first 3-6 months
- Men and women >50 years old on Prednisone 5 mg/day for 3 months, or three steroid bursts in 6 months should undergo DEXA Scan
-
Electronic Cigarette (psych, cd)
- Increasing use by teens (up to 1 in 9 in high school), and associated with 4 fold increased risk of Tobacco Abuse
- More than 80% of teens believe e-cigs are harmless
-
Hyperhidrosis (derm, sweat)
- OTC Aluminum Chloride is as effective as prescription items
- Obrexza is an expensive ($550/month) second-line adjunct for axillary sweating refractory to other topicals
IV. Updates: October 2018
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Well Child Visit (prevent, hme, peds)
- Screen for Postpartum Depression at visits for infants <6 months of age
- Perform Developmental Screening at 9, 18 and 30 months (minimum) and Autism screening at 18 and 24 months
- Visual Acuity screening at least once at age 3-5 years
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Hemolytic Anemia (hemeonc, Hemolysis)
- Mechanisms include immune (AIHA), microangiopathic (MAHA), oxidative (e.g. G6PD Deficiency)
- Initial testing includes a CBC, Peripheral Smear, Direct Coombs, Total and Indirect Bilirubin, Basic metabolic panel, Lactate Dehydrogenase, Urinalysis
- Plasmic Score may be useful in suspected Thrombotic Thrombocytopenic Purpura
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Small Bowel Obstruction (surgery, bowel)
- Closed loop obstruction, Volvulus, Strangulated Hernia are surgical emergencies
- CT Abdomen is a first line study over plain XRay for high suspicion obstruction
-
Lactation (ob, Lactation)
- Breast Feeding is recommended for 1-2 years (exclusively for the first 6 months) with decreased infection risks, higher IQ for infants
- Most common causes of Lactation cessation are insufficient milk supply, inadequate latching and painful nipples or Breasts
- Effective Breast Feeding Signs may be monitored to ensure adequate intake
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Low Back Pain (ortho, L-spine, sx)
- Most Low Back Pain resolves with conservative therapy and most measures are ineffective beyond NSAIDS and non-medication management
- Imaging is not indicated unless Low Back Pain Red Flags or persistent and significant pain at 6 weeks
- McKenzie Method entails an initial assessment by methodology trained PT and then individualized self treatment
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Abdominal Wall Pain (surgery, gi, pain, Muscle)
- Abdominal Wall Pain is under-recognized as a common cause of persistent or recurrent Abdominal Pain
- Nerve entrapment is a common cause of Abdominal Wall Pain
- Consider Trigger Point Injection with or without Corticosteroid
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Anemia in Older Adults (hemeonc, geri, Anemia)
- Low Serum Ferritin is consistent with Iron Deficiency Anemia, but a high Serum Ferritin may be increased as an acute phase reactant
- Consider endoscopy in older adults with Iron Deficiency Anemia
- For those with Iron Deficiency but intolerant to Iron Supplementation, consider 15 mg elemental iron suspension dissolved in orange juice
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Cervical Spine Injury (ortho, c-spine)
- Follow ATLS protocol with inline spinal immobilization, ABC Management, Primary Survey and Secondary Survey
- Use decision rules (e.g. NEXUS, Canadian C-Spine Rule) to determine imaging indications (see Cervical Spine Imaging in Acute Traumatic Injury)
- Consider Neck Vascular Injury in Blunt Force Trauma
- Be aware of Neuropraxia (Stingers and Transient Quadriplegia) as diagnoses of exclusion, and keep other Cervical Spine Injury causes in mind
-
Sepsis (id, fever)
- Surviving Sepsis 2018 is being criticized for squeezing the 3 hour and 6 hour bundles into 1 hour without much evidence to support the change
-
Medications in Pregnancy (OB, pharm)
- As you know by now, FDA Pregnancy Categories will be replaced on medication bottles with specific warnings and precautions by 2020 in U.S.
- As of 2018, succinct guidance (to replace ABCDX) on specific drugs in pregnancy is lacking
- In pregnancy, balance medication risks with drug benefits and the risk of untreated conditions (e.g. Diabetes Mellitus, Asthma, Seizure Disorder)
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Exercise-Induced Anaphylaxis (ent, sports)
- Exercise with or without food triggers can result in Urticaria as well as Anaphylaxis
- Immune Complex Inhibitors (hemeonc, pharm)
- Another class of monoclonal antibodies for cancer
- Includes CTLA-4 (e.g. Ipilimumab), PD-1 (e.g. Pembrolizumab), PDL-1 (e.g. Atezolizumab )
- Adverse effects include potentially serious toxicity, Autoimmune Conditions, Diarrhea and rashes
-
Esophageal Foreign Body (gi, Esophagus, fb)
- Esophageal Bougie has become a first-line measure in children to push single coins from the Esophagus into the Stomach
-
Diaper Rash (derm, peds)
- Keep the diaper area dry, and clean with hypoallergenic wipes at diaper changes
- Use barriers such as petroleum jelly, Zinc Oxide or aquaphor
- If Topical Corticosteroids are used, limit to level 6-7, low potency agents
- Consider Antifungals if persistent rash >5 days consistent with Candida Diaper Dermatitis
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Depression Management in Cardiovascular Disease (psych, cv, depression)
- Major DepressionPrevalence after MI may approach 50% and increases risk of future cardiovascular events and increases mortality
-
Essential Oils (pharm, alternative)
- Limited evidence of benefit when used for Aromatherapy, and unlikely to cause harm when inhaled
- Topical use can cause local reactions and systemic effects on absorption, and oils should be diluted before application
- Avoid ingestion (esp. in children)
-
Actinic Purpura (derm, environ, sun)
- Sun Damaged Skin in the elderly develop purple patches and Ecchymosis
-
Mass Casualty Incident (er, Trauma)
- Prepare before patients arrive, by moving as many patients out of the ED as possible (admitted patients to ward, ESI 4-5 home with follow-up appts)
-
Hypertensive Emergency (cv, htn, er)
- Lower systolic Blood Pressure to <140 mmHg in Subarachnoid Hemorrhage and <180 mmHg in Intracerebral Hemorrhage
- Lower systolic Blood Pressure to <220 mmHg in Cerebrovascular Accident and <185 mmHgif using tPA for CVA
- Keep systolic Blood Pressure >100-110 mmHg in Closed Head Injury
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Pediatric Emergency Care (er, peds)
- Children may have longer lasting behavioral change after even minor ED procedures with or without sedation
-
Agitated Delirium (psych, behavior)
- Physical Restraints are a high risk procedure that should be run like a code and kept briefly until Sedation of the Violent Patient is adequate
-
Laceration Repair (surgery, derm)
- Avoid loose wound closure
- If closing a potentially contaminated wound, choose either primary closure or by second intention
-
Placenta Previa (ob, bleed)
- Painless Vaginal Bleeding after 18-20 weeks is Placenta Previa until proven otherwise
-
Liposuction (surgery, procedure)
- High volume Liposuction >5 liters may result in significant Fluid Shifts, Syncope, Pulmonary Edema
-
Breast Implant (surgery, procedure)
- Bleeding after implant placement may occur in the first 24 hours requiring return to surgery
V. Updates: September 2018
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Bone Cancer (hemeonc, cancer, bone, Sarcoma)
- Bone Cancers include Osteosarcoma, Ewing Sarcoma, and much less common, Chondrosarcoma
- Osteosarcoma is most common, affects age 5-25 years old, more common in black males, and is treated with Chemotherapy and resection
- Ewing Sarcoma is most common in mid-teen years and is more common in white or asian males
- Chondrosarcoma is the least common Bone Cancer, affects ages 45-75 years and is treated with surgical resection, and Radiation Therapy in some cases
-
Preoperative Examination in Older Adults (surgery, Anesthesia, geri)
- Always consider whether surgical benefits outweigh the risks in older patients with major comorbidities, low functional capacity, reduced Life Expectancy
- Evaluate neurologic status (Dementia, Delirium, decision making capacity, Major Depression)
- Evaluate Activities of Daily Living, Fall Risk, Frailty, nutritional status
- Review Medication Use in the Elderly for inappropriate medications (e.g. Beers List, STOPP)
-
Nutrition in Toddlers (pharm, peds, nutrition)
- Do not limit fat intake under age 1 year (but may limit to 30-40% of total kcals at age 1-3 years)
- At ages 1-2 years, whole milk 16 oz/day, limit 100% Juice to 4 oz/day and the rest water (avoid sugar drinks)
- Avoid special diets (e.g. gluten free) unless medically indicated
-
Lithium Toxicity (psych, pharm, adverse)
- May present with Nausea, Vomiting, Diarrhea and sluggishness, Ataxia, confusion, Agitation or Tremors, esp. in chronic Lithium Toxicity
- Peak levels may not be reached for >12 hours after Overdose
- For a given level, symptoms may be more mild in acute toxicity than in chronic toxicity
- First-line management is IV hydration; severe cases may require Hemodialysis
-
Annular Lesion (derm, exam)
- Common causes include Tinea Corporis, nummular Eczema, Urticaria, Erythema Multiforme, Erythema Migrans, Lichen Planus
-
Foot Pain (ortho, sx, foot)
- Plantar Fasciitis is a condition of micro-tears, not of inflammation; NSAIDs and steroid injections are unlikely to offer significant benefit
- Salicylic acid is as effective for Plantar Warts as Cryotherapy and as Sharp Debridement for corns
- Proper Shoe Fit is a key preventive strategy for overall foot conditions
-
Long-Acting Reversible Contraception (gyn, pharm)
- Nexplanon is the only Contraceptive Implants (Etonogestrel Progesterone Implants) available in the U.S.
- Intrauterine Devices (IUD) include the Copper T IUD, as well as Mirena and Kyleena (5 year), Liletta (4 year) and Skyla (3 year)
- Difficult IUD Removal (Missing IUD Strings, embedded IUD) and difficult implant removal techniques are explored
- Geriatric Emergency Care (geri, er)
-
Valsartan (cv, pharm, htn)
- Valsartan is recalled for contamination by NDMA, a known carcinogen
-
Drowning (sports, er, water)
- Avoid using antiquated terms (e.g. near Drowning, wet Drowning, dry Drowning)
- Immediately get patient to land, lay supine, and initate CPR, starting with ventilations (do not perform heimlich to "clear the lungs")
- Manage Hypothermia with rewarming, and do not cease Resuscitation attempts until warmed to >34-35 C
-
Fascia Iliaca Block (ortho, procedure, hip)
- Consider in isolated Femoral Neck Fracture
-
Opioid Withdrawal (psych, cd, Opioid)
- Consider Emergency department initiated Buprenorphine (single dose) with follow-up scheduled within days in those seeking treatment
- Patient should be experiencing at least moderate Opioid Withdrawal at time of dose
- Buprenorphine may be administered for up to 3 dose over 72 hours in the Emergency Department without a FDA X-Waiver
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Big Pharma (pharm, manage)
- Pharmaceutical companies have decades of work, billions of dollars of potential sales hinging on study results
- Newly introduced drugs are typically backed by studies that overestimate benefit and underestimate risk
- Negative studies are not published and adverse outcomes are suppressed in published reports
- Manipulation of control groups, statistical techniques, study duration
-
Acute Coronary Syndrome Immediate Management (cv, cad)
- Up to 30-30% with NSTEMI may have complete coronary Occlusion and would benefit from PCI
- ST Elevation criteria for leads V2 and V3 are age and gender dependent (2.5 mm for man <40, 2 mm for man>40, 1.5 mm for woman)
- ST depression >1mm in 8 or more leads and ST Elevation in aVR or V1 suggests left main obstruction or multi-vessel disease
-
Bradycardia (cv, ekg)
- BRASH Syndrome is Bradycardia, Renal Failure, AV Blocker (e.g. Beta Blocker, Calcium Channel Blocker), Shock, Hyperkalemia
- Type 2 Diabetes Preparations (endo, dm, pharm)
-
ASCVD Risk Calculator (cv, exam, cad, prevent)
- Since 2013, ACC/AHA ASCVD Risk Calculator has replaced Framingham Calculator
-
Gout (rheum, joint)
- Febuxostat may increase mortality from cardiovascular disease in those with known CAD
-
Quinolone (id, pharm, Bacteria)
- More warnings about Quinolones
- Hypoglyemia in those using Quinolones with Sulfonylureas or Insulin, especially in the elderly, renal Impairment
-
Recurrent Urinary Tract Infection (urology, id, Bladder)
- Methenamine may be effective for short term UTI prophylaxis in patients without renal tract abnormalities
- Cranberry Juice appears less effective than originally found in initial studies (may reduce symptomatic Recurrent UTI in women)
-
Prescription Cannabinoid (gi, pharm)
- Epidiolex is a purified Cannabidiol indicated for rare Seizure Disorders at $32,500 per year
-
Lice (derm, Parasite)
- The OTC agents are still worth a try (despite resistance) along with combing
VI. Updates: August 2018
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Stimulant Use Disorder (psych, cd)
- Methamphetamines, MDMA, Cocaine and Bath Salts continue to present to emergency departments with serious stimulant effects
- Consider Stimulant Use Disorder in those with altered behavior, neuropsychiatric changes, labile Vital Signs
- Almost half of Chemical Dependency goes undiagnosed in primary care
-
Breaking Bad News (hemeonc, psych)
- Several mnemonics are available to guide an approach to Breaking Bad News
-
Type I Diabetes Mellitus (endo, dm)
- Early aggressive Insulin management with A1C maintained<7% reduces morbidity and mortality rates, sustained for decades
- Self-monitoring of Blood Glucose is associated with better Glucose control
- Insulin Pump is selected by more than half of type I diabetics, but multiple daily basal and bolus injections offers similar efficacy
-
Connective Tissue Disease (diffuse, rheum)
- Limit rheumatologic testing (e.g. ANA, RF) to cases of higher clinical suspicion given the high rate of positives in the unaffected population
- When higher suspicion for Connective Tissue Disease, only obtain specific Antibody testing when ANA is positive
-
Chronic Nonallergic Rhinitis (ent, nose)
- Reclassification of non-allergic non-Infectious Rhinitis of which subtypes include Vasomotor Rhinitis and Nonallergic Rhinitis with Eosinophilia
- Rhinorrhea predominant symptoms are treated with intranasal Atrovent first
- Congestion predominant symptoms are treated with Intranasal Corticosteroids and/or intranasal Antihistamines
-
Congestive Heart Failure Exacerbation Management (cv, chf, er)
- Consider causes of acute CHF decompensation (e.g. medication or dietary non-compliance, ACS, Arrhythmia)
- Start with NIPPV and Nitroglycerin in hypertensive CHF, and consider ACE Inhibitor, Diuretics
- History, exam and Bedside Ultrasound are typically more effective as diagnostic tools than BNP
- Consider Ottawa Heart Failure Risk Score to risk stratify very low risk patients to discharge (most will require admission)
-
Fever in the Returning Traveler (id, fever, travel)
- Careful history of travel timing, regions, exposures is critical to identifying likely causes
- Be vigilant and consider personal protection, when evaluating a febrile traveler who may need isolation (e.g. hemorrhagic fever, MERS)
- Excluding Malaria is key, even in mild illness, even in those who took chemoprophylaxis
-
Pericarditis (cv, Pericardium)
- Children with significant Pericarditis (large Pericardial Effusion, Myocarditis) may present with subtle findings (e.g. Sinus Tachycardia, Puffy Eyelids)
-
Hypokalemia (renal, Potassium)
- Obtain EKG for Potassium <3.0 mEq/L and observe for QTc Prolongation
- For every Serum Potassium drop of 0.3 mEq/L, total body Potassium deficit increases 100 mEq
- Consider empiric Magnesium Replacement with Potassium Replacement (e.g. 400-500 mg twice daily for 3 days)
-
Chronic Kidney Disease (renal, failure)
- CKD patients die of Coronary Artery Disease. Prescribe a Statin, ACE Inhibitor, Aspirin
- Significant medication adjustments start at Creatinine Clearance <30 mg/dl
-
Nitrofurantoin (id, pharm, Antibiotic)
- Short-term Nitrofurantoin use (<14 days) is safe down to GFR 30 ml/min
-
Flumist (id, immunize, virus)
- In 2018, Flumist is once again an option for influenza Vaccination, albeit likely still less effective than other influenza Vaccination options
- Consider Flumist in healthy, non-pregnant patient aged 2 to 49 years who would otherwise refuse Influenza Vaccine
-
Migraine Prophylaxis (neuro, Headache)
- Erenumab (Aimovig) is a new, expensive ($7000/year) biologic, monthly SQ Injection for Migraine Prophylaxis
- Indicated when other first-line Migraine Prophylaxis options have been exhausted
-
Sunburn (derm, environ)
- Treat as minor Burn Injury with cool compresses and inert Skin Lubricants (e.g. eucerin)
- Avoid benzocaine, Corticosteroids and home remedies (e.g. butter, apple cider vinegar, buttermilk, lavender oil)
-
Procedural Sedation and Anesthesia (surgery, Anesthesia)
- Prepare to protect the airway against closure and pulmonary aspiration and to recognize early Hypotension, Hypoxia, and apnea
- Hypotension and apnea most often occur with Propofol and with Benzodiazepines (esp. with Opiates)
- Be prepared for specific Sedative (e.g. Ketamine) adverse effects (e.g. larygospasm, emergence)
-
Methotrexate (rheum, ra, dmaard)
- MethotrexateOverdose or toxicity is potentially lethal if not treated
- Optimize Urine Output and alkalinize the urine
- Administer folinic acid or Leucovorin to bypass Methotrexate induced blockade of dihydrofolate reductase and supply active Folate
- Administer Glucarpidase (if available), an expensive enzyme that breaks down Methotrexate (and unfortunately Leuocovorin)
-
Serum Magnesium (renal, Magnesium)
- Serum Magnesium represents only 1 to 1.5% of total body Magnesium (of which only 50% is active, ionized)
- Magnesium levels tend to vary widely (e.g. with respiration) and single values are unlikely to be useful
- Serum Potassium tends to be a surrogate marker for Serum Magnesium
- Hypokalemia is typically accompanied by Hypomagnesemia (consider empiric Magnesium Replacement at the time of Potassium Replacement)
-
Provider Burnout (manage, psych)
- Acute stress may us more effective in emergencies, but chronic stress is maladaptive and leads to burnout
- Consider self actualization pyramid of needs (physiologic, safety, love and belonging and self esteem)
- Maintain Exercise, Healthy Diet, adequate sleep, and get together with colleagues, family and friends
-
Peripheral IV Access (er, procedure)
- Two additional techniques for difficult Peripheral IV Access
- Tourniquet Infusion Technique uses an already placed small IV to infuse 100 cc NS and a Tourniquet above the elbow results in Forearm venous engorgement for second IV
- Central Vein Placement of peripheral IV targets an internal Jugular Vein under Ultrasound guidance with a peripheral IV (48 mm long is ideal if available)
VII. Updates: July 2018
-
Appendicitis (surg, gi)
- Cefotetan and Unasyn with Clindamycin are no longer considered adequate pre-surgical Antibiotics due to resistance
- Skilled bedside Appendix Ultrasound is a first-line test in the evaluation of Appendicitis in children and pregnant women
-
Recurrent Abdominal Pain Syndrome (surg, peds, gi)
- Functional Abdominal Pain is a clinical diagnosis and diagnostic testing is not needed unless red flag findings are present
- Consider Cognitive Behavioral Therapy and Probiotic supplementation
- Localized Prostate Cancer (urology, hemeonc, Prostate)
- Reviewed active surveillance of localized Prostate Cancer
-
Health Concerns in the Elderly (geri, prevent)
- Review Beers Criteria and STOPP Criteria, as well as medication indications before starting a new medication
- Preventive evaluations should include Fall Risk, Major Depression, Hearing Loss, Cognitive Impairment and Immunization updating
-
Allergy Testing (ent, lab, allergy)
- Skin Testing for Penicillin Allergy can prevent the overuse of broader spectrum Antibiotics
- Food Allergy testing has a high False Positive Rate and should only be performed based on a specific history
-
Medical Decision-Making Capacity (neuro, cognitive)
- Ability to communicate, understand the information they are given
- Ability to make logical decisions based on given information
- Ability to understand their current medical status or condition
- Ability to understand options for medical care
-
Compartment Syndrome (ortho, neuro)
- Have a high index of suspicion to check Compartment Pressures when pain is out of proportion to findings
- Pulse loss and weakness are late findings and their absence does not exclude limb threatening pressures
- Emergency Fasciotomy delayed >4-6 hours may result in permanent injury or even limb loss
-
Anticoagulant Overdose (hemeonc, pharm, coags, adverse)
- Consider Activated Charcoal if ingestion within 1-2 hours (may be effective with DOACs up to 8 hours)
- Intentional Overdose: Observe for bleeding for 24 hours (or per poison control) before medically cleared to psychiatry
- Unintentional Overdose: If small quantity (e.g. one extra dose) may discharge home with bleeding precautions
- Risk of significant bleeding 5% after Anticoagulant Overdose
- Emergency Department Observation Unit (ed, cv)
- Established protocols exist for Atrial Fibrillation, CHF and PE that are cost effective, safe, shorter duration, with added quality and consistency
- Observation protocols have clear inclusion, exclusion and discharge criteria to ensure good patient selection and best outcomes
-
Emergency Psychiatric Evaluation (psych, exam)
- Reviewed strategies for emergency mental health evaluation in children
- Consider HEADS-ED as a disposition tool
-
Gonorrhea (id, std)
- Gonorrhea has growing Incidence and resistance, and dual coverage with Ceftriaxone and Zithromax is preferred
- Retest all patients in 3 months for new, reinfection
- Andexxa (hemeonc, pharm, coags)
- Oxycontin (pharm, Analgesic, Opioid)
-
Acute Pain Management (pharm, Analgesic)
- Limit Opioids for acute pain to 3 days in most patients (7 days in nearly all patients)
- Avoid non-cancer Chronic Opioids
-
Ketamine (surgery, pharm)
- Ketamine is often used as a very effective and safe pre-hospital Chemical Restraint
- Ketamine at high dose (4-5 mg/kg) results in GCS 3, but typically maintained respiratory drive (GCS-3K)
- Many providers prematurely intubate based on ED arrival GCS 3 (despite Ketamine induced)
- However, with close monitoring, Ketamine sedated patients may be safely observed without intubation
- Supraventricular Tachycardia Management in the Adult (cv, ekg)
-
Sunscreen (derm, pharm, environ)
- Two chemical Sunscreens (Oxybenzone, Octinoxate) will be banned in Hawaii as of 2021 due to adverse effects to ocean wildlife (coral bleaching, reproduction)
- Physical Sunscreens (Titanium Dioxide, Zinc Oxide) are nanoparticle products despite labeling ("non-nano")
- None of the physical Sunscreens are absorbed through the skin regardless of size (nano or "non-nano")
- Nanoparticle Sunscreens are typically easier to apply
-
Genetic Test (lab, gene)
- Home Genetic Tests (e.g. 23andMe) are becoming more available in which patients mail in a cheek swab sample for DNA analysis
- Tests only a subset of available Genetic Tests at a cost of several hundred dollars and risk of both False Positives and false reassurance when testing is incomplete
- Genetic Counseling is preferred for test interpretation and test selection based on patient history
-
Crohns Disease (gi, ibd)
- TNF Agents are becoming first-line over Sulfasalazine, Mesalamine, Corticosteroids
VIII. Updates: June 2018
-
Discipline (peds, prevent)
- Provide anticipatory guidance at visits on positive parenting
- Assist with effective behavior changing approaches
-
Developmental Disorder in Adults (prevent, hme)
- Speak directly to patients using the communication methods they are able to use
- Focus on adaptive interventions that allow patients to live in their home or community
- Specific approaches to common problems include Constipation, Osteoporosis, aspiration, Decubitus Ulcer, behavior changes
-
Colorectal Cancer Prevention (gi, prevent, hemeonc, bowel)
- Screening options include Colonoscopy every 10 years or FOBT (guiaic-based or FIT immunochemical) annually
- Although Virtual Colonoscopy and Flexible Sigmoidoscopy are other screening options, they have significant disadvantages
- For average risk patients, screening starts at age 50 years and ends at 75-85 years old
- The only significantly effective lifestyle changes that have impact on CRC are weight loss, Physical Activity, and avoiding red meat
-
Oncologic Emergency (hemeonc, sx, er)
- Consider Tumor Lysis Syndrome esp. in hematologic malignancies following Chemotherapy or Radiation Therapy
- Consider Hypercalcemia of Malignancy esp. in Multiple Myeloma and Breast Cancer in those with confusion, weakness, Vomiting
- Consider SIADH esp. in Small Cell Lung Cancer with often asymptomatic Hyponatremia
- Exercise caution in Febrile Neutropenia, and start early empiric Antibiotic management for best outcomes
-
Hyperhidrosis (derm, sweat)
- Exclude secondary Hyperhidrosis Causes (including Medication Causes of Hyperhidrosis)
- Aluminum hydroxide 20% (Drysol) is a first-line therapy for all regions of primary Hyperhidrosis
- Iontophoresis is effective for palmar and planter Hyperhidrosis
- Onabotulinum Toxin A intradermal injection is effective for Hyperhidrosis on the palms, soles, axilla and face
-
Atrial Fibrillation Anticoagulation (cv, ekg, atrialfib coags)
- Apixaban (Eliquis) may be the preferred DOAC with best Atrial Fib efficacy and lowest adverse effect profile
- Andexxa, a factor 10a Inhibitor reversal agent is pending release in 2018
-
EMS Transport (er, manage, ems)
- Air transport (aside from rescue helicopters) offer mobile ICU level care typically staffed by an ICU nurse, advanced Paramedic or physician
- Helicopters travel at 100-150 mph, at <3000 feet and are limited by visibility
- Fixed wing aircraft are preferred for >100 mile distance and travel at 250 to 600 mph, at high altitude with cabins pressurized to 7000 feet
-
Pneumaturia (urology, sx)
- May be due to Bladder instrumentation (cystoscopy), fistula from bowel or vagina, renal tumor infarction, urinary diversion or Scuba Diving with p-valve
- However, it is critical to exclude UTI with gas forming organisms (e.g. Proteus, E. coli, Klebsiella, Candida, Clostridium)
- UTI with gas forming organisms may result in Emphysematous Cystitis or Emphysematous Pyelonephritis which are associated with high mortality
- Staghorn calculi and low Urine pH may indicate the presence of gas forming organisms
-
Abdominal Aortic Aneurysm (surgery, gi)
- The classic triad of Abdominal Pain or back pain, Hypotension and pulsatile abdominal mass is present <50% of the time
- Keep a high index of suspicion for AAA in >50-60 year old patients (esp. men) with back pain or abominal pain
- Consider bedside abdominal aortic Ultrasound (turn color doppler on, apply pressure and be patient to allow gas to settle)
-
CVA Management (neuro, cv)
- DAWN study shows benefit for endovascular intervention in selected patients with CVA up to 24 hours after onset
-
Syncope (cv, sx)
- All Syncope patients should have an EKG; additional testing is directed by a thorough history and physical
- Emergency department evaluation identifies 80% of syncopal causes
- In the absence of high risk criteria, syncopal patients may be discharged from the ED with follow-up
-
Loperamide Abuse (gi, pharm)
- Loperamide crosses the blood brain barrier when taken in very high dose or when in combination with P-Glycoprotein Inhibitor (e.g. Cimetidine)
- LoperamideOverdose is associated with QTc Prolongation and risk of fatal Arrhythmia
-
Emergency Psychiatric Evaluation (psych, exam)
- As with adults undergoing Emergency Psychiatric Evaluation, lab testing in children should be targeted by history and exam
- Use Verbal De-escalation techniques in children to prevent the need for escalation to Chemical Restraints and Physical Restraints
-
Clinical Decision Rule (manage, legal, risk)
- Decision rules allow risk stratification, standardization of risky presentations, and limit testing with adverse effects (e.g. radiation exposure)
- Use decision rules that have been prospectively validated, refined and used in clinical practice and in combination with clinical gestalt
- Avoid applying the decision tool to patients outside the population studied (inclusion and exclusion criteria)
- Avoid mashing multiple decision tools together (use each decision tool individually, in the way it was validated)
-
Postoperative Bleeding after Tonsillectomy (Ent, Surgery, Mouth, Bleed)
- Tonsillar bleeding occurs with sloughing of Fibrin clot day 5-10 in 2-7% of post-Tonsillectomy patients
- Bleeding control can be challenging especially in children
- Consider nebulized Tranexamic Acid (TXA)
- Ketamine (surgery, pharm)
-
Syphilis (id, std)
- Incidence continues to rise in U.S. (now 8 per 100,000)
- Review primary, secondary and tertiary presentations, esp. dermatologic findings
-
Asthma Biologic (lung, Asthma, pharm)
- Consider Biologic Agents for Severe Persistent Asthma
-
Depression in Children (psych, peds, depression)
- Depression is common in teens (1 in 5) - screen each year for depression with PHQ-2 and advance to full PHQ-9 as needed
- Cognitive therapy is the most effective first line treatment for Childhood Depression
- Most effective Antidepressants include Fluoxetine, Escitalopram, Sertraline
- More expensive drugs (pharm)
- Vitamin K costs $50 per 5 mg tablet
- Naloxone autoinjectors are still $125, and $4900 if your device is to speak to you
- Epinephrine Autoinjectors are still $600 and up to $4900
- Another HIV Treatment me-too drug (Biktarvy)
- Lonhala Magnair is a new LAMA for COPD at $1100 per month
-
Synthetic Cannabinoid (psych, cd)
- Anticoagulant-laced Synthetic Cannabinoids have resulted in life threatening bleeding
IX. Updates: May 2018
-
Running Injury (sports, Running)
- Most common Running injuries include Patellar Tendinopathy, Patellofemoral Syndrome, Achilles Tendonitis, Iliotibial Band Syndrome
- Keep Tibial Stress Fractures in the differential diagnosis (esp. with Shin Splints)
-
Osteoarthritis (rheum, Osteoarthritis)
- Diagnosis is typically clinical with onset after age 50 years, pain with activity (esp. late in the day), and pain in fingers, Shoulders, hips, knees
- Analgesics, avoiding provocative activity and in some cases joint replacement are effective treatments
- Unfortunately Glucosamine and joint steroid and viscoreplacement injections offer minimal to no benefit
-
Group A Streptococcus (id, Bacteria)
- Numerous complications (which are now much less common in the U.S.) including Rheumatic Fever, PSGN, PANDAS, Poststreptococcal Reactive Arthritis
- Keep Rheumatic Fever in the differential when seeing children with Reactive Arthritis or neuropsychiatric symptoms (Sydenham Chorea)
-
Croup (lung, airway)
- Humidified oxygen offers no benefit over standard oxygen
- Administer Corticosteroids to croup of any severity
- Nebulized Epinephrine for moderate to severe croup and observe for 2-3 hours
-
Charcot Foot (rheum, neuro)
- Consider Charcot Foot in the >40 year old with Peripheral Neuropathy, Obesity, and minimally painful swollen, red, warm foot without fever
- Charcot Foot is misdiagnosed on average for 7 months, delaying diagnosis, and risking deformity and amputation
-
Pediatric Limp (rheum, sx, peds)
- Consider Nonaccidental Trauma in nonambulatory or developmentally delayed children with Fractures
- Limp is not always a lower extremity problem (consider back, hip and Pelvis causes)
- AP Pelvis may miss hip pathology (nearly always obtain frog-leg Pelvis)
- Back pain is rare in children (consider serious causes such as Discitis, referred abdominal source, Nonaccidental Trauma)
-
Medication Use in the Elderly (geri, pharm)
- Consider noncompliance, OTC Medications and Herbals when evaluating adverse drug events
- Consider taking a medication away, instead of starting a new medication, in older patients
- Anticoagulants (esp. Warfarin), diabetic medications (esp. Insulin) and Digoxin account for the most common adverse drug events in elderly
-
Pediatric Congestive Heart Failure (cv, peds, chf)
- Viral Myocarditis (e.g. Parvovirus B19, HH6, Kawasaki's, enterovirus) can be life threatening in infants
- Acute presentations for "URI" may reveal a sicker infant with Tachycardia out of proportion progressing to Acute Respiratory Failure
-
Necrotizing Fasciitis (derm, id)
- Necrotizing Fasciitis is a life threatening infection with an insidious, occult presentation
- Do not ignore pain out of proportion, Sinus Tachycardia or unexplained fever
- Do not delay surgical exploration when Necrotizing Fasciitis is suspected
-
ST Elevation (cv, exam, ekg)
- Consider alternative causes of ST Elevation, including neurologic catastrophe (e.g. Subarachnoid Hemorrhage)
- Marijuana Toxicity (psych, cd)
-
Hypertension in Diabetes Mellitus (dv, endo, htn)
- Diabetes Mellitus targets move once again to <130/80 for everyone per ACC/AHA, but <140/90 per ADA in non-high risk patients
-
Cocaine-Induced Coronary Vasospasm (cv, cad)
- MI Relative Risk increases to 24 fold over baseline (risk increases within first hour of use and persists for 4-7 hours)
- Acute Cocaine Intoxication causes tachyarrhythmias, Hypertension, prothrombotic state, QT Prolongation, QRS Widening
- Chronic Cocaine use increases coronary atherosclerosis, Cardiomyopathy, Pulmonary Hypertension and stroke risk
-
Drugs of Abuse (psych, cd)
- Substances of abuse are difficult to distinguish by sight
- White powder could be Cocaine, Methamphetamine, synthetic Opioids, NBOMe or bath salts
- Crystals could be Crystal Meth, U-47700
- Many substances of abuse are reformulated into tablets (e.g. Fentanyl may be formed in tablets similar to Oxycodone or Hydrocodone)
-
Gastric Lavage (er, pharm, toxin)
- Rarely indicated in modern Emergency Medicine
- Consider in Overdoses that approach 100% mortality (consult poison control) such as Colchicine Overdose, Paraquat Poisoning (herbacide used outside the U.S.)
- May also consider in Hydrofluoric Acid ingestion due to risk of lethal Hyperkalemia and Hypocalcemia
-
Rhus Dermatitis (ent, allergy, derm)
- Corticosteroid course of 14-18 days is preferred due to risk of rebound with shorter courses
-
Emergency Department Triage System (er, exam)
- ESI 3 is the achilles heal of the Emergency Severity Index (50% are triaged to ESI 3)
- Techniques to optimize ESI 3 flow include provider in triage, split flow, vertical triage and most recently, electronic triage
-
Limited Ultrasound for Acute Renal Colic (uro, renal)
- More evidence that Ultrasound is a safe, effective approach to Renal Colic
-
Nocturia (uro, Bladder, sx)
- Noctiva (low dose Desmopressin) - another expensive drug with marginal efficacy, real risk (Hyponatremia)
- Treat Nocturia instead by identifying, treating and optimizing the underlying causes of Nocturia
-
Ottawa Aggressive Atrial Fibrillation Protocol (cv, ekg)
- In stable patients with Atrial Fibrillation <48 hours, consider Procainamide 1 g over 1 hour, then electrical cardioversion if fails
X. Updates: April 2018
-
Stable Coronary Artery Disease (cv, cad)
- High intensity Statin for age <75 years
- Blood Pressure control with Beta Blocker, ACE Inhibitor, Thiazide Diuretic, optimally <130/80 and keep <140/90
- Low dose Aspirin 81 mg is sufficient for most patients
- Encourage aerobic Exercise, Tobacco Cessation, Influenza Vaccine
-
Chronic Pancreatitis (gi, Pancreas)
- CT Abdomen is first line imaging followed by MR/MRCP, then EUS, and finally ERCP if other testing non-diagnostic
- Malabsorbtion and steatorrhea occur when <10% pancreatic exocrine function remains, at which point enzyme replacement is indicated
-
Dementia (neuro, cognitive)
- Dementia Screening with Mini-Cog, GPCOG, or Ascertain Questionnaire, and diagnosis with SLUMS, Addenbrooke or MMSE
- Evaluation includes CBC, TSH, Vitamin B12, Serum Glucose and MRI Brain
- Exclude Major Depression, medications, infections and other causes of Delirium
-
Cervical Cancer (gyn, hemeonc)
- Cervical Cancer Screening has eased with no screening before age 21 years, and cytology and/or HPV screening at 3-5 year intervals
- Except for Stage IA1, Cervical Cancer management typically involves radical Hysterectomy, pelvic lymphadenectomy and chemoradiation
-
Rheumatoid Arthritis (rheum, ra)
- Methotrexate is the preferred first line DMARD in most cases
- Do not start Biologic Agent (e.g. tnf agent) before a trial on Methotrexate or similar DMARD
- Screen for Tuberculosis, Hepatitis B, Hepatitis C and Skin Cancer before starting a Biologic Agent
- Consider tapering DMARD if in remission for at least 6 months (esp. if anti-citrullinated Protein negative)
-
Rheumatoid Arthritis in the Emergency Department (rheum, ra)
- CV presentations - MI, CHF, Atrial Fibrillation, Pulmonary Hypertension, PE, Pleural Effusion, Pericardial Effusion
- ID presentations due to RA, TNF agents, steroids, such as Pneumonia, opportunistic infections
- In Joint Pain presentation, exclude Septic Arthritis, even if underwhelming signs
- Treat Rheumatoid Arthritis flare after excluding Septic Joint with Prednisone taper, 60-10 mg over 2 weeks
-
Clarithromycin (id, pharm)
- Observational studies find possible increase in cardiovascular deaths while on Clarithromycin
-
Clostridium difficile (gi, Diarrhea)
- Vancomycin is becoming first-line for C. Diff over Flagyl even in first episode except in mild cases
-
Fentanyl Patch (pharm, Analgesic)
- Fentanyl Patches should only be used for Chronic Pain with patients using at least 60 mg Morphine per day
-
Prescription Cannabinoids (gi, pharm)
- Consider in wasting, Anorexia, intractable Nausea for patients with AIDS, cancer, Chemotherapy
-
Lactic Acid (renal, lab)
- Lactic Acid is primarily used as a Sepsis marker and tissue ischemia marker, e.g. Ischemic Bowel, but differential diagnosis of Lactic Acidosis is broad
- Avoid ordering Lactic Acid in low risk patients, non-toxic, previously healthy
- Lactic Acid clearance outside Sepsis does not uniformly improve with Intravenous Fluids
- Cardiogenic Shock can also increase Lactic Acid and will worsen with excess fluids
- Abdominal Trauma in Pregnancy (er, ob)
- Abdominal tenderness and maternal Vital Sign changes are often absent despite significant hemoperitoneum
- Maternal stabilization and needed imaging, even if requiring ionizing radiation, takes precedence
- Give RhoGAM even in minor Trauma in Rh Negative women
-
Transesophageal Echocardiogram (cv, rad)
- Consider in Cardiac Arrest, as may be monitored without interruption and not interfere with Resuscitation efforts
- Heart function, compression quality and Great Vessels are seen without chest wall or epigastric bowel gas obstruction
- Distinguishes cardiac standstill, true PEA or Asystole, from ineffective contraction and may identify Cardiac Tamponade, PE with RV strain, vascular rupture
-
Sickle Cell Anemia (hemeonc, Hemoglobin)
- Treat sickle cell vaso-occlusive crisis aggressively with early IV Opioids
- Have a high index of suspicion for serious Bacterial Infection in febrile children <5 years old
- Always consider Acute Chest Syndrome in "Pneumonia" in Sickle Cell Anemia
- Splenic Sequestration is a life threatening complication
-
Chance Fracture (Ortho, L-spine, Fracture, Trauma)
- High velocity Traumatic Injury, e.g. MVA with Lap belt only, causes flexion and distraction of the thoracolumbar spine
- Results in unstable, transverse Fracture through the anterior, middle and posterior Vertebral body, that typically requires surgical repair
- Associated with cord injury, aorta injury, Liver Laceration, Splenic Rupture and mesentary and Small Bowel injury Pediatric Cervical Spine Injury (ortho, peds, c-spine)
- New radiculopathy or Myelopathy (hyperreflexia, Clonus, babinski, weakness), esp. if bilateral, requires MRI prior to discharge (even if negative CT)
- MRI for ligamentous instability with subluxation, Central Cord Syndrome, Vertebral Fracture
XI. Updates: March 2018
-
Nutrition Guidelines (pharm, nutrition)
- Healthy Kitchens, Healthy Lives conferences emphasizes delicious, plant forward food choices
- Vegetables and fruits should be 50% of diet and whole grains 25%
- Replace red meat with nuts, legumes, fish and poultry; limit dairy, and use monounsaturated fats
-
Sexual Assault of Male Victim (prevent, abuse)
- Woods lamp is ineffective at visualizing semen (but UV light is effective)
-
Migraine Headache (neuro, Headache)
- NSAIDS are first-line for mild-moderate Migraines and Triptans are first-line for mild-moderate Migraines
- Dopamine Antagonists (e.g. Reglan, Compazine) are preferred Antiemetics in Migraine Headache
- Acetaminophen and Metoclopramide are preferred agents in pregnancy
- Acetaminophen, NSAIDs and Triptans are preferred in children
-
Testicular Cancer (urology, hemeonc, Testes)
- Testicular Cancer screening is not recommended in asymptomatic men (USPTF)
- Testicular Cancer peaks at age 30-34 years
- Thorough update of staging, management and surveillance
-
Vitamin D (pharm, Vitamin)
- Vitamin D Deficiency is defined as Vitamin D <12-20 ng/ml
- Vitamin D screening is not routinely recommended
- Vitamin D testing or supplementation is not indicated in Major Depression, Fatigue, Osteoarthritis or Chronic Pain
-
Opioid Use Disorder (psych, cd)
- Buprenorphine is a common partial opioid Agonist used in Medication-Assisted Treatment
- Combined Buprenorphine/Naloxone agents are preferred over Buprenorphine alone for lower abuse potential
- Buprenorphine prescribers requires special DEA licensing
-
Colorectal Cancer (gi, hemeonc)
- Follow-up after resection is typically every 3-6 months for 2-3 years, then every 6 months until 5 years post-resection
- CEA is tested at each follow-up visit
- CT chest, Abdomen and Pelvis is done every year for 5 years in Stage 3-4, and high risk Stage 1-2
- Colonoscopy is at 1 and 3 years after resection and then every 5 years (unless advanced adenoma is found)
-
Intimate Partner Violence (prevent, abuse)
- Screen all patients with atypical presentations for abuse regardless of gender, race, age or LGBT
- Provide abuse victims with the resources and help they are willing to accept, with an open offer for additional help as they are willing to accept it
- Help patients develop a safety plan (emergency shelter and point person, emergency bag, important papers)
-
Electrocardiogram (cv, exam)
- Do not rely on computerized EKG Interpretation (aside from interval measurement)
- There is no standardization for software quality across EKG manufacturers and accuracy varies widely
- Computer interpretations miss STEMIs in up to 23-41% of cases
- Atrial Fibrillation is a frequent False Positive on computer interpretations
-
Vaginitis (gyn, vagina)
- Symptoms do not distinguish Vaginitis cause (history, exam and labs are best used for accurate diagnosis)
- Single DNA tests (e.g. BD Affirm) are available to test for Trichomonas, Bacterial Vaginosis and candida infection
- DNA Testing is preferred for Trichomonas diagnosis, and can be added to DNA probe and liquid pap
- Bacterial Vaginosis treatment in pregnancy improves symptoms, but does not lower risk of Preterm Labor
- Drug Activity in Women (pharm, gyn)
-
Musculoskeletal Injuries in Women (sports, gyn)
- Women athletes are higher risk for ACL Tears, PFS, Patellar Subluxations, Stress Fractures, elbow and Shoulder Dislocations and Concussions
-
Sulfonylurea Drug Interactions Causing Hypoglycemia (endo, pharm)
- Sulfonyureas (esp. Glyburide) are a risk for Hypoglycemia
- Drug Interactions (e.g. Fluoroquinolones, Clarithromycin, sulondamides, Fibrates) can increase the risk of drug-induced Hypoglycemia
-
Mediastinal Widening (lung, rad)
- Emergent causes include Aortic Dissection, Aortic Rupture, Pneumomediastinum, Thoracic Aortic Aneurysm, Vertebral Fracture with Hematoma
- Other causes include lung or Mediastinal Mass or adenopathy, Hiatal Hernia, Atelectasis, Thymus or Thyroid mass or anatomic variant
- Imaging technique (rotation, supine position, AP view, poor inspiration) commonly results in wide mediastium appearance
-
Procedural Sedation and Analgesia (surgery, Anesthesia)
- Ketamine is the preferred procedural Anesthetic in children with the least adverse effects
-
MMR Vaccine (id, immunize)
- MMR Vaccine booster (3rd dose) is indicated in outbreaks if directed by local public health (esp. in dormitories, barracks)
- As always, avoid MMR in pregnancy and Immunocompromised
- Give a second dose, if never immunized (or unknown status), at 4 weeks after the first
-
Urinary Tract Infection in Pregnancy (urology, ob, id)
- Cephalexin, Cefuroxime, and Fosfomycin (expensive) may be used in any trimester (as well as Amoxicillin, which has higher resistance)
- Nitrofurantoin should not be used in late third trimester (Hemolytic Anemia risk) and may be very weakly associated with heart defects, Cleft Lip
- Trimethoprim-Sulfamethoxazole may only be used in second and early third trimester
-
Steroid-Induced Hyperglycemia (endo, pharm)
- Blood Glucose will typically increase with Systemic Corticosteroids
- Most diabetes patients do not require significant changes to regimen when on short courses of Corticosteroids
- Risk of Hypoglycemia as steroid is tapered outweighs benefit of transiently increased regimen
- Closer monitoring and tighter Glucose management on Corticosteroids in Type I Diabetes Mellitus, uncontrolled Type 2 Diabetes Mellitus
-
Rhabdomyolysis (renal, failure)
- Rhabdomyolysis is divided into exertional (typically benign) and non-exertional (worse outcome)
- Initial Creatinine kinase level does not predict outcome unless >40,000
- Acute Kidney Injury is associated with a worse outcome
- Aggressive fluid hydration is key within first 6 hours (urine out >250 cc/h), but crystalloid type and alkalinization have not been shown to matter for outcome
-
Influenza (id, virus)
- Avoid Elderberry and Oscillococcinum (unlikely to be helpful)
-
Low Back Pain Management (ortho, L-Spine)
- Valium does not add benefit over Naprosyn alone for Low Back Pain
- Most will improve within 3 months of Acute Low Back Pain onset (but 20% will still have a functional deficit)
-
Tympanic Membrane Perforation (ent, ear)
- Do not use cortisporin with a perforated Ear Drum
- ENT referral for most cases, esp. for large perforation, suspected ossicle disruption, Vertigo
- Use Antibiotic drops (e.g. Ofloxacin, Ciprofloxacin) which are at 100x oral concentrations, for associated Otitis Media with or without oral Antibiotics
-
Neonatal Circulation Assessment (nicu, exam, cv)
- Minimize blood loss in newborns
- Newborn Blood Volume: 85 ml/kg
- Newborn weighing 4 kg has only 340 ml total Blood Volume
- Every 34 ml (slightly more than 2 Tbs or 1 oz) is 10% of total Blood Volume
-
Alcohol Intoxication (psych, cd)
- Hypoglycemia, Abnormal Vital Signs or chemical sedation needed are markers of underlying Critical Illness in the intoxicated patient
-
Appendix Ultrasound (surgery, rad)
- AppendicitisUltrasound accuracy is improving
- Test Sensitivity is as high as 92% in radiology (80% at ED bedside)
- Test Specificity is as high as 97% in radiology (92% at ED bedside)
-
Surfer Spine (sports, water)
- Atraumatic Spinal Myelopathy from cord infarction is an uncommon condition seen primarily in warm water Surfing (e.g. Hawaii) by amateur surfers
- May be associated with prolonged hyperextended position
- Presents with sudden onset of back pain, bilateral leg weakness, Paresthesias
XII. Updates: February 2018
-
Penile Lesion (urology, penis, derm)
- Papulosquamous lesions include Psoriasis and pearly Papules
- Inflammatory lesions include Lichen Sclerosus, Lichen Nitidus, Lichen Planus
- Vascular lesions include Angiokeratomas
- Neoplastic lesions include Penile Carcinoma in Situ, penile squamous cell cancer
-
Heel Pain (ortho, ankle, foot)
- Midfoot lateral pain includes Peroneal Tendinopathy and Sinus Tarsi Syndrome
- Midfoot medial pain includes flexor digitorum Tendinopathy or tibialis posterior Tendinopathy
- Posterior plantar Foot Pain includes Plantar Fasciitis, Heel Pad Syndrome, Tarsal Tunnel Syndrome, Calcaneal Stress Fracture
- Posterior Heel Pain includes Achilles Tendinopathy, Retrocalcaneal Bursitis, Haglund Deformity and in children, Severe Disease
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Colorectal Cancer Screening (gi, procedure, hemeonc)
- Standard Colorectal Cancer Screening starts at age 50, but for those meeting Family History criteria, start at age 40 (or 10 years before youngest relative)
- Specific screening protocols are defined for high risk syndromes: HNPCC, IBD, adenomatous polyposis, Peutz-Jeghers Syndrome, Sessile serrated polyposis
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Hemorrhoid (gi, Rectum)
- Fiber supplementation with adequate hydration is first-line management of Hemorrhoids
- Excise Thrombosed Hemorrhoids in the first 48-72 hours; Nifedipine or Nitroglycerin may be adjunctive for pain
- Most effective surgical interventions include Rubber band ligation (grade I-III) and surgical excision (grade III-IV)
- Exercise caution when attributing Rectal Bleeding to Hemorrhoids (esp. in age >40 years or other Colon Cancer or Inflammatory Bowel Disease risks)
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Tremor (neuro, Tremor)
- Essential Tremor is the most common pathologic Tremor, an Action Tremor progressive with age, a diagnosis of exclusion made clinically
- Most Rest Tremors are Parkinsonism (although other causes include drug-induced and psychogenic can cause similar findings)
- Urgently refer children with Tremor
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Bullying (peds, behavior)
- Bullying is much more common than previously reported (each year, 20% in schools and 16% online)
- Start discussing Bullying at the 6 year old well child check
- Bullying victims commonly have Insomnia, Abdominal Pain, Headaches as well as Major Depression, Suicidality, poor school performance, Eating Disorders
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Hypothermia (er, environ)
- In Frostbite, do not massage or apply dry heat
- In Hypothermia, measure a core Temperature with a Thermometer with adequate lower range, and consider Secondary Hypothermia causes
- In severe Hypothermia, ECMO continues to offer better outcomes when core Temperature is <28 C or if hemodynamic instability
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Abdominal Ultrasound (gi, rad)
- Several protocols exist for evaluating the Abdomen with Ultrasound including for free air, Small Bowel Obstruction and localizing Epigastric Pain
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STEMI (cv, cad)
- STEMI with Hypotension mayh be due to right ventricular infarct, Aortic Dissection, massive Pulmonary Embolism, Cardiac Tamponade, ventricular rupture
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Head Injury (er, neuro)
- Warfarin-related delayed CNS bleeding after Head Injury is uncommon (<2%) and typically does not warrant intervention
-
Cardiac Arrest (er, exam)
- Consider a brief moment of silence at the end of code in which the patient expired
- Chlorine (er, toxin)
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Ketorolac (pharm, Analgesic)
- Ketorolac 10 mg IV is as effective for analgesia as 15 or 30 mg
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Fever Without Focus Management Birth to 3 Months (id, peds)
- Well appearing febrile infants at 60 days of age have a 1.8% Prevalence of bacteremia
- Cannabinoid Hyperemesis Syndrome (psych, cd)
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Sudden Sensorineural Hearing Loss (ent, Hearing)
- Prednisone 50-60 mg orally daily while awaiting ENT followup
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Traumatic Cardiopulmonary Arrest (er, cv)
- Unless medical Cardiac Arrest, immediate interventions (chest Ultrasound, Finger Thoracostomy) take precedence over CPR in Traumatic Arrest
- Consider Finger Thoracostomy instead of Needle Thoracostomy (both of which are best done at the 5-6th intercostal space axillary line)
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Oral Contraceptives (gyn, pharm)
- Even low dose Estrogen increases Breast Cancer risk by RR 1.2
-
Biotin (pharm, Vitamin)
- Biotin supplementation for hair, nails... has little data of efficacy
- High dose Biotin (>5000 mcg) falsely lowers Thyroid Stimulating Hormone, Troponin and Procalcitonin
- Altitude sickness (er, environ)
- Consider prophlaxis with Diamox if traveling to >11,000 feet in one day (or 9000 if prior history of altitude sickness)
- Medications (pharm)
- Many new, expensive, copy-cat drugs
- Do we really need more GLP-1, SGLT2 Inhibitor agents for diabetes or biologics for Psoriasis or combo HIV agents?
- Who is working on new Antibiotics or reasonably priced cancer regimens?
- Long Acting Beta Agonist (lung, Asthma, pharm)
- FDA takes away a black box warning on LABAs (apparently mortality was no worse than with Inhaled Corticosteroids)
XIII. Updates: January 2018
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Chronic Kidney Disease (renal, failure)
- Serum Cystatin C may be used in place of Serum Creatinine to estimate Glomerular Filtration Rate
- Urine Albumin to Creatinine Ratio is the preferred method to evaluate for Proteinuria
- Use Urine Protein to Creatinine Ratio in severe Proteinuria (>300 mg/g)
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Pigmentation Disorder (derm, pigment)
- Several Hyperpigmentation disorders (e.g. Melasma, Solar Lentigines, Postinflammatory Hyperpigmentation) respond to tri-luma
- Start with Topical Corticosteroids for Localized Vitiligo, and UVB for generalized Vitiligo
- Sun protection and Sunscreen are a key to the management of Pigmentation Disorders
-
Palpitations (cv, sx)
- Most Palpitations will be due to psychosomatic disorders, Atrial Fibrillation, SVT
- Every person with Palpitations should have an EKG at minimum
- Supraventricular Premature Complexes (SVPCs) are associated with risk of Atrial Fibrillation and cardiac events
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Hypertension Criteria (cv, htn)
- Once again ACC/AHA has moved the targets on Blood Pressure goals based on new studies
- Is this sound, given Blood Pressure reading inaccuracies, prescriber confusion, medication and lifestyle noncompliance
-
Hypothyroidism (endo, Thyroid, pharm)
- Subclinical Hypothyroidism may be treated if TSH >10, persistent symptoms (Fatigue, Constipation, cold intolerance) or pregnancy
- Avoid desiccated Thyroid and Liothyronine (T3) in most cases
-
Automobile Safety (prevent, car, pharm)
- Ilicit drugs and prescribed Benzodiazepines and other Sedative-Hypnotics, Muscle relaxants, Opioids, Anticholinergics may cause Impaired Driving
-
Opioid Dependency (psych, cd, pharm)
- Naltrexone is revisted for maintenance of Opioid sobriety
-
Topical Corticosteroids (derm, pharm)
- Once again, pharmaceutical companies have found a way to double prices on Generic Drugs (e.g. Topical Clobetasol)
-
Long-Acting Beta Agonist (copd, pharm)
- Trelegy Ellipta for severe COPD combines a LAMA, LABA and Corticosteroid
-
Bronchiolitis (lung, Bronchi)
- Hypertonic Saline does not reduce hospitalization rates in Bronchiolitis
-
Nonphysiologic Neonatal Jaundice (nicu, gi)
- Not much has changed in Hyperbilirubinemia management in the last couple of decades
- Use calculators (e.g. BiliTool.com) to assess the need for Phototherapy
- Consider secondary causes (e.g. Neonatal Sepsis)
-
Idarucizumab (hemonc, pharm, coags)
- Idarucizumab reverses Dabigatran (Pradaxa) rapidly (minutes) and effectively
-
Low Risk Chest Pain (cv, cad)
- Stress testing in Low Risk Chest Pain increases angiograms and revascularization without reducing MI related admissions
-
Cardiac Arrest (er, exam)
- Bedside Ultrasound increases the delays to restarting Chest Compressions
- Delayed Sequence Intubation (lung, procedure)
-
Hyperemesis Gravidarum (ob, gi)
- Fewer labs needed (No Thyroid tests unless symptoms of Hyperthyroidism, Urine Ketones are not markers of illness severity)
- Metoclopramide and Ondansetron are first line Antiemetics
-
Endotracheal Intubation Preoxygenation (lung, procedure)
- Oops Mnemonic (Levitan): Oxygen On, Apply 15 lpm by Nasal Cannula for Apneic Oxygenation, Pull Mandible forward, Sit patient up (to 20 degrees)
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Acromioclavicular Separation (ortho, Shoulder)
- Obtain comparison view of unaffected side, but weighted films are not needed
-
Ankle Fracture (ortho, ankle, Fracture)
- Weber B Ankle Fracture stability is predicted by <2 mm posterior fragment displacement and only 2 Fracture fragments
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Noninvasive Urine Collection (urology, lab)
- Alternative techniques to stimulate urination in young children (pre-Toilet Training) are highly effective
- Quick-Wee Method (forceps with cold saline soaked gauze rubbed on suptrapubic area)
- Bladder stimulation technique (infants <1 month), with infant suspended by axilla, tap on Bladder, than circular massage low back
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Brown Recluse Spider Bite (er, derm, bite)
- Immediately ice bite wounds to deactivate toxin
- Skin necrosis starts at 72 hours after bite
- NOT RECLUSE mnemonic is used to exclude brown recluse bites as wound cause in endemic areas
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Informed Consent (neuro, cognitive)
- Provider performing the procedure should also perform the Informed Consent
-
Otitis Externa (ent, ear)
- Combine Topical Antibiotic with a Topical Corticosteroid (e.g. cipro-hc, cipro-dex, Ofloxacin and Dexamethasone)
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Insulin Dosing in Type 2 Diabetes (endo, pharm)
- Updated protocol for initiating Basal insulin only and advancing to basal and Bolus Insulin (Insulin augmentation)
- Updated protocol for initiating and advancing to basal and Bolus Insulin (Insulin replacement)
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Ear Pain (ent, sx, ear)
- Consider referred Ear Pain, esp. cancer risk, CAD risk and Temporal Arteritis risk
- Pityriasis Rosea (derm, hyperplasia)