II. Prevention

  1. Sunscreen
    1. SPF 15 daily, starting in childhood
    2. SPF 30 during spring and summer
  2. Tobacco Cessation

III. Management: General Measures

  1. Maintain hydration
  2. Tobacco Cessation
  3. Frequent Skin Lubricant use

IV. Management: Topical Agents

  1. Retinoid
    1. Tretinoin (Retinoic Acid, Vitamin A Acid, Retin A) starting at 0.025% Cream 1-2 times per week qhs (may use OTC)
    2. Adapalene (Differin)
    3. See Retin A for adverse effects
      1. Must wear Sunscreen daily
  2. Alpha-Hydroxy acids (Lac-Hydrin 12%) or Urea 3-6%
    1. Combine with Skin Lubricant

V. Management: Other Adjuncts

  1. Estrogen Replacement Therapy
  2. Topical Estrogen
  3. Antioxidants and other additives
    1. Vitamin C (questionable efficacy)
    2. Vitamin E
    3. Hyaluronic acid

VI. Management: Skin Cosmetic Procedure

  1. See Skin Cosmetic Procedure
  2. Chemical Peels
  3. Derm Abrasion
  4. Laser Abrasion

VII. Management: Avoid Ineffective Measures for Wrinkles and Skin Damage

VIII. References

  1. (2021) Presc Lett 28(1): 4-5

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