II. Pathophysiology: Predisposing factors
- Decreased tissue perfusion oxygenation
- Peripheral fluid stasis and edema
- Increased Skin Trauma risk
- Suppressed immune function
III. Types: Bacterial Skin Infections (Pyoderma)
IV. Types: Complicated Bacterial Skin Infections
V. Types: Fungal Skin Infection
VII. Types: Viral Skin Infections
VIII. Risk Factors
-
Immunodeficiency
- Asplenia
- Diabetes Mellitus (5 fold increased SSTI risk)
- HIV Infection
- Chemotherapy
- DMARDs (Rheumatoid Arthritis)
- Chronic Disease
- Comorbidity (e.g. cardiopulmonary, hepatorenal, debility)
- Dialysis (ESRD)
- Longterm intravascular access (MRSA risk)
- Lymphedema
- Obesity
- Peripheral Neuropathy
- Peripheral Artery Disease
- Trauma or surgery
- Eczema and other Pruritic Conditions
- Demographics
- Children and older adults (MRSA risk)
- Healthcare Worker
- Prolonged hospitalization (MRSA risk)
- Longterm Care (MRSA risk)
- Military (close quarters)
- Athlete
- Lifestyle
- Alcohol Abuse
- Nutritional deficiency
- IV Drug Abuse
- Water exposure (swimming in lakes, hot tubs)
IX. Classification
- Class 1
- Simple infection without systemic symptoms or signs of spread
- No uncontrolled comorbidities impacting treatment
- Outpatient Antibiotic management planned
- Class 2
- Infection with systemic symptoms or signs of spread (e.g. fever, sweats, Tachycardia) or
- Uncontrolled comorbidities impacting treatment or
- ParenteralAntibiotics required
- Class 3
- Infection with systemic symptoms or signs of spread (e.g. fever, sweats, Tachycardia) or
- Uncontrolled comorbidities impacting treatment
- Inpatient ParenteralAntibiotics required
- Class 4
- Infection with life-threatening systemic symptoms or signs of spread (e.g. severe Sepsis)
- Inpatient management with ParenteralAntibiotics (may require ICU care)
- Surgical Consultation may be warranted