II. Pathophysiology: Predisposing factors
- Decreased tissue perfusion oxygenation
- Peripheral fluid stasis and edema
- Increased Skin Trauma risk
- Suppressed immune function
III. Types: Bacterial Skin Infections (Pyoderma)
IV. Types: Complicated Bacterial Skin Infections
V. Types: Fungal Skin Infection
VII. Types: Viral Skin Infections
VIII. Risk Factors
-
Immunodeficiency
- Asplenia
- Diabetes Mellitus (5 fold increased SSTI risk)
- HIV Infection
- Chemotherapy
- DMARDs (Rheumatoid Arthritis)
- Chronic Disease
- Comorbidity (e.g. cardiopulmonary, hepatorenal, debility)
- Dialysis (ESRD)
- Longterm intravascular access (MRSA risk)
- Lymphedema
- Obesity
- Peripheral Neuropathy
- Peripheral Artery Disease
- Trauma or surgery
- Eczema and other Pruritic Conditions
- Demographics
- Children and older adults (MRSA risk)
- Healthcare Worker
- Prolonged hospitalization (MRSA risk)
- Longterm Care (MRSA risk)
- Military (close quarters)
- Athlete
- Lifestyle
- Alcohol Abuse
- Nutritional deficiency
- IV Drug Abuse
- Water exposure (swimming in lakes, hot tubs)
IX. Classification
- Class 1
- Simple infection without systemic symptoms or signs of spread
- No uncontrolled comorbidities impacting treatment
- Outpatient Antibiotic management planned
- Class 2
- Infection with systemic symptoms or signs of spread (e.g. fever, sweats, Tachycardia) or
- Uncontrolled comorbidities impacting treatment or
- ParenteralAntibiotics required
- Class 3
- Infection with systemic symptoms or signs of spread (e.g. fever, sweats, Tachycardia) or
- Uncontrolled comorbidities impacting treatment
- Inpatient ParenteralAntibiotics required
- Class 4
- Infection with life-threatening systemic symptoms or signs of spread (e.g. severe Sepsis)
- Inpatient management with ParenteralAntibiotics (may require ICU care)
- Surgical Consultation may be warranted
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Related Studies
| Definition (CHV) | pus-producing skin infection |
| Definition (CHV) | pus-producing skin infection |
| Definition (MSH) | Any purulent skin disease (Dorland, 27th ed). |
| Concepts | Disease or Syndrome (T047) |
| MSH | D011711 |
| ICD9 | 686.00, 686.0 |
| ICD10 | L08.0 |
| SnomedCT | 200719000, 267838007, 156323008, 70759006 |
| English | Pyoderma, Pyodermas, DERMATITIS PYOGENIC, PYODERMA, Pyo infect of skin and subcut, pyodermia, pyoderma (diagnosis), pyoderma, septic dermatitis, suppurative dermatitis, Dermatitis pyogenic, Pyoderma (skin infection), Pyoderma NOS, Pyoderma [Disease/Finding], Pyoderma NOS (disorder), Purulent dermatitis, Pyodermia, Pyogenic dermatitis, Septic dermatitis, Suppurative dermatitis, Pyogenic infection of skin and subcutis, Pyoderma (disorder), lesion; skin, suppurative, pyodermatitis, skin; lesion, suppurative, Pyoderma, unspecified, Dermatitis, purulent, Dermatitis, septic, Dermatitis, suppurative |
| French | PYODERMITE, Dermatite à pyogène, Pyodermite (infection cutanée), Dermite purulente, Dermite septique, Dermite suppurée, DERMITE A PYOGENES, Pyodermite, Pyodermie |
| Spanish | PIODERMA, Dermatitis piógena, Pioderma (infección cutánea), DERMATITIS PIOGENICA, pioderma, SAI, pioderma, SAI (trastorno), dermatitis piógena, dermatitis purulenta, dermatitis supurativa, dermatitis séptica, pioderma, piodermia, piodermitis (trastorno), piodermitis, Piodermia, Pioderma |
| German | PYODERMIE, Pyodermie (Hautinfektion), Dermatitis pyogen, DERMATITIS PYOGEN, Pyodermie |
| Dutch | pyoderma (huidinfectie), dermatitis pyogeen, huid; lesie, etterig, lesie; huid, etterig, pyoderma, Pyodermie |
| Italian | Dermatite piogena, Pioderma (infezione cutanea), Pioderma |
| Portuguese | Piodermite (infecção cutânea), Dermatite piogénica, DERMATITE PIOGENICA, PIODERMITE, Piodermite, Pioderma |
| Japanese | 膿皮症（皮膚感染）, 化膿性皮膚炎, 膿皮症, ｶﾉｳｾｲﾋﾌｴﾝ, ﾉｳﾋｼｮｳ, ﾉｳﾋｼｮｳﾋﾌｶﾝｾﾝ |
| Swedish | Pyoderma |
| Czech | pyodermie, Pyogenní dermatitida, Pyodermie |
| Finnish | Pyoderma |
| Russian | PIODERMIIA, ПИОДЕРМИЯ |
| Korean | 농피증 |
| Polish | Zapalenie skóry ropne, Piodermia, Zapalenie skóry ropowicze |
| Hungarian | pyoderma, Pyoderma (bőrfertőzés), Dermatitis, pyogen |
| Norwegian | Pyoderma |
Ontology: Skin Diseases, Infectious (C0037278)
| Definition (MEDLINEPLUS) |
Your skin helps protect you from germs, but sometimes it can get infected by them. Some common types of skin infections are
Treatment of skin infections depends on the cause. |
| Definition (MSHCZE) | Nemoci kůže způsobené bakteriemi, plísněmi, parazity nebo viry. |
| Definition (NCI) | An inflammatory process affecting the skin, caused by bacteria, viruses, parasites, or fungi. Examples of bacterial infection include carbuncles, furuncles, impetigo, erysipelas, and abscesses. Examples of viral infection include shingles, warts, molluscum contagiosum, and pityriasis rosea. Examples of parasitic infection include scabies and lice. Examples of fungal infection include athlete's foot, yeast infection, and ringworm. |
| Definition (NCI_CTCAE) | A disorder characterized by an infectious process involving the skin. |
| Definition (MSH) | Skin diseases caused by bacteria, fungi, parasites, or viruses. |
| Definition (CSP) | skin diseases caused by bacteria, fungi, parasites, or viruses; may present on the surface of the skin, or underlying dermal layers. |
| Concepts | Disease or Syndrome (T047) |
| MSH | D012874 |
| SnomedCT | 267839004, 156325001, 19824006, 108365000 |
| English | Disease, Infectious Skin, Diseases, Infectious Skin, Infectious Skin Disease, Infectious Skin Diseases, Skin Disease, Infectious, Skin Diseases, Infectious, SKIN INFECTION, Skin infections, INFECT SKIN DIS, SKIN DIS INFECT, Skin infection NOS, Skin Diseases, Infectious [Disease/Finding], infection of skin, Infection;skin, infectious skin diseases, infectious skin disease, Skin Infections, Skin infections NOS, Skin--Infections, Skin infection, Infection of skin (disorder), Infection of skin, infection; skin, skin; infection, Skin Infection, skin infection |
| Italian | Infezione della cute, Infezione della cute NAS, Malattie infettive della pelle |
| Dutch | huidinfectie NAO, huid; infectie, infectie; huid, huidinfectie, Huidziekte, infectieuze, Huidziekten, infectieuze, Infectieuze huidziekte, Infectieuze huidziekten |
| French | Infection cutanée SAI, Infections de peau, INFECTION CUTANEE, Infection cutanée, Dermatoses infectieuses, Infections cutanées, Infections de la peau, Maladies infectieuses de la peau |
| German | Hautinfektion NNB, Hautinfektion, Hautkrankheiten, infektiöse |
| Portuguese | Infecção cutânea NE, INFECCAO CUTANEA, Infecção cutânea, Dermatopatias Infecciosas |
| Spanish | Infección cutánea NEOM, Enfermedades Cutáneas Infecciosas, Dermatopatías Infecciosas, Enfermedades Infecciosas de la Piel, infección cutánea, infección de la piel (trastorno), infección de la piel, Infección cutánea |
| Japanese | 皮膚感染, ﾋﾌｶﾝｾﾝ, 皮膚感染ＮＯＳ, ﾋﾌｶﾝｾﾝNOS, 皮膚疾患-感染性, 感染性皮膚疾患, 皮膚感染症 |
| Swedish | Hudsjukdomar, infektiösa |
| Finnish | Ihoinfektiot |
| Russian | KOZHNYE BOLEZNI INFEKTSIONNYE, КОЖНЫЕ БОЛЕЗНИ ИНФЕКЦИОННЫЕ |
| Czech | Infekce kůže, Kožní infekce NOS, kožní nemoci infekční, kůže - nemoci infekční, infekční nemoci kůže, infekční kožní nemoci |
| Croatian | KOŽNE BOLESTI, INFEKTIVNE, INFEKTIVNE KOŽNE BOLESTI |
| Polish | Choroby skóry zakaźne |
| Hungarian | bőrfertőzés k.m.n., bőrfertőzés |
| Norwegian | Infeksiøse hudsykdommer, Hudinfeksjoner |
Ontology: Skin and subcutaneous tissue infections and infestations (C0851477)
| Concepts | Disease or Syndrome (T047) |
| Italian | Infezioni ed infestazioni della cute e del tessuto sottocutaneo |
| Japanese | 皮膚および皮下組織感染および外寄生, ﾋﾌｵﾖﾋﾞﾋｶｿｼｷｶﾝｾﾝｵﾖﾋﾞｶﾞｲｷｾｲ |
| Czech | Infekce a parazitární onemocnění kůže a podkožní tkáně |
| English | Skin and subcutaneous tissue infections and infestations |
| Hungarian | Bőr és subcutan szövet fertőzések és infestatiók |
| Portuguese | Infecções e infestações da pele e tecido celular subcutâneo |
| Spanish | Infecciones e infestaciones de la piel y del tejido subcutáneo |
| Dutch | huid- en onderhuidsweefselinfecties en -infestaties |
| French | Infections et infestations de la peau et du tissu sous-cutané |
| German | Infektionen und Befall der Haut und des Unterhautzellgewebes |
Ontology: Skin and subcutaneous arthropod and parasitic infestations (C0852350)
| Concepts | Disease or Syndrome (T047) |
| Italian | Infestazioni della cute e del tessuto sottocutaneo da artropodi e parassiti |
| Japanese | 皮膚・皮下組織内節足動物寄生および寄生虫症, ﾋﾌﾋｶｿｼｷﾅｲｾｯｿｸﾄﾞｳﾌﾞﾂｷｾｲｵﾖﾋﾞｷｾｲﾁｭｳｼｮｳ |
| Czech | Napadení kůže a podkožní tkáně členovci a parazity |
| English | Skin and subcutaneous arthropod and parasitic infestations |
| Hungarian | Bőr és subcutan ízeltlábú és parazita infestatiók |
| Portuguese | Infestações da pele e tecido subcutâneo por artrópodos e parasitas |
| Spanish | Infestaciones cutáneas y subcutáneas por artrópodos y parásitos |
| Dutch | huid en subcutane artropoden en parasitaire infestatie |
| French | Infestations parasitaires et ectoparasitaires de la peau et du tissu sous-cutané |
| German | Arthropoden- und Parasitenbefall der Haut und des Unterhautzellgewebes |
Ontology: Skin and subcutaneous tissue fungal infections (C0852352)
| Concepts | Disease or Syndrome (T047) |
| Italian | Infezioni micotiche della cute e del tessuto sottocutaneo |
| Japanese | 皮膚・皮下組織真菌感染, ﾋﾌﾋｶｿｼｷｼﾝｷﾝｶﾝｾﾝ |
| Czech | Mykotické infekce kůže a podkožní tkáně |
| English | Skin and subcutaneous tissue fungal infections |
| Hungarian | Bőr és subcutan szövet gombás fertőzései |
| Portuguese | Infecções micóticas da pele e do tecido celular subcutâneo |
| Spanish | Infecciones por hongos de la piel y del tejido subcutáneo |
| Dutch | huid en subcutaan weefsel schimmelinfecties |
| French | Infections mycosiques de la peau et du tissu sous-cutané |
| German | Pilzinfektionen der Haut und des Unterhautzellgewebes |
Ontology: Parasite infestation (C1384353)
| Concepts | Disease or Syndrome (T047) |
| SnomedCT | 17322007 |
| Italian | Infestazione |
| Japanese | 寄生, ｷｾｲ |
| English | infestation, infestation (diagnosis), infectious disease - parasites, parasitic infestation, infectious disease - parasites (diagnosis), Infestation, infestation; parasite, parasite; infestation, Infestation, NOS, Parasite infestation, NOS, Parasite infestation |
| Czech | Zamoření |
| Hungarian | Infestatio |
| Dutch | infestatie; parasiet, parasiet; infestatie, infestatie |
| Spanish | infestación por parásitos, infestación, Infestación |
| Portuguese | Infestação |
| French | Infestation |
| German | Befall |
