Definition (NCI)
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A combination of the semisynthetic broad-spectrum antibiotic amoxicillin and the beta-lactamase enzyme inhibitor clavulanate potassium. Clavulanate potassium increases the serum half-life of amoxicillin by inhibiting beta-lactamase-mediated metabolism of amoxicillin. Amoxicillin inhibits bacterial cell wall synthesis by binding to penicillin binding proteins and inhibiting peptidoglycan synthesis, a critical component of bacterial cell walls.
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Definition (NCI)
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A fixed combination of Amoxicillin and Clavulanic Acid, which inhibits beta-lactamase, a bacterial enzyme that inactivates amoxicillin.
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Definition (NCI_NCI-GLOSS)
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A drug used to treat bacterial infections. Adding the chemical clavulanate potassium to the antibiotic amoxicillin increases the amount of time the antibiotic stays active in the body. Amoxicillin-clavulanate potassium is a type of combination antibiotic.
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Definition (MSH)
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A fixed-ratio combination of amoxicillin trihydrate and potassium clavulanate.
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Definition (PDQ)
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A combination of the semisynthetic broad-spectrum antibiotic amoxicillin and the beta-lactamase enzyme inhibitor clavulanate potassium. Clavulanate potassium increases the serum half-life of amoxicillin by inhibiting beta-lactamase-mediated metabolism of amoxicillin. Amoxicillin inhibits bacterial cell wall synthesis by binding to penicillin binding proteins and inhibiting peptidoglycan synthesis, a critical component of bacterial cell walls. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=40783&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=40783&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C1023" NCI Thesaurus)
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Concepts |
Antibiotic
(T195)
, Organic Chemical
(T109)
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MSH |
D019980
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SnomedCT |
387514006, 89519005 |
LNC |
LP15420-0, MTHU006777 |
English |
Amox-clav, Amoxi Clavulanate, Amoxi-Clavulanate, Amoxicillin Potassium Clavulanate Combination, Amoxicillin-Potassium Clavulanate Combination, Amoxycillin, Clavulanate Potentiated, Clavulanate Potentiated Amoxycillin, Clavulanate-Amoxicillin Combination, Potassium, Combination, Potassium Clavulanate-Amoxicillin, Potassium Clavulanate Amoxicillin Combination, Potassium Clavulanate-Amoxicillin Combination, Potentiated Amoxycillin, Clavulanate, AMOXICILLIN/CLAVULANATE, Amox clav, amoxicillin-clavulanic acid, amoxicillin + clavulanic acid, amoxicillin + clavulanic acid (medication), amoxicillin-clavulanate, Amoxicillin-Potassium Clavulanate Combination [Chemical/Ingredient], Amoxicillin / Clavulanate, amox-clav, co amoxiclav, coamoxiclav, amoxycillin clavulanic acid, amox clav, acid amoxicillin clavulanic, acid amoxycillin clavulanic, amoxicillin with clavulanic acid, co-amoxiclav, amoxi-clavulanate, amoxicillin clavulanate, amoxicillin clavulanic acid, Amoxycillin with clavulanate potassium (substance), Amoxicillin+Clavulanate, Amoxicillin-Clavulanate, Amoxicillin with clavulanic acid, Amoxycillin with clavulanate potassium, Amoxycillin with clavulanate potassium (product), amoxicillin-clavulanate potassium, Co-amoxiclav, Amoxicillin Clavulanic Acid, Amoxicillin-Clavulanic Acid, Amoxycillin Clavulanic Acid, Amoxycillin-Clavulanic Acid, Co amoxiclav, Coamoxiclav, Amoxicillin-Clavulanate Potassium, Amoxicillin and Clavulanate Potassium, Amoxicillin and Clavulanate |
Swedish |
Amoxicillin-kalium-klavulansyrakombination
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Czech |
amoxicilin-kyselina klavulanová, kombinace amoxicilin-klavulanát draselný |
Finnish |
Amoksisilliini-kaliumklavulanaatti-yhdistelmä
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Russian |
AMOKSITSILLINA-KALIIA KLAVULANATA KOMBINATSIIA, AMOKSITSILLIN-KLAVULANOVAIA KISLOTA, АМОКСИЦИЛЛИН-КЛАВУЛАНОВАЯ КИСЛОТА, АМОКСИЦИЛЛИНА-КАЛИЯ КЛАВУЛАНАТА КОМБИНАЦИЯ |
Japanese |
クラブラン酸-アモキシシリン, クラブラン酸カリウム-アモキシシリン混合剤, アモキシシリン-クラブラン酸カリウム混合剤, アモキシシリン-クラブラン酸 |
Italian |
Amoxi-clavulanato, Amoxicillina-acido clavulanico, Amox-clav, Co-amoxiclav, Amoxicillina potenziata con clavulanato, Combinazione di clavulanato di potassio e amoxicillina |
Polish |
Amoksycylina z solą potasową kwasu klawulanowego, Połączenie amoksycyliny z solą kwasu klawulanowego |
Spanish |
amoxicilina con clavulanato de potasio (sustancia), amoxicilina con clavulanato de potasio (producto), amoxicilina con clavulanato de potasio, amoxicilina con ácido clavulánico (producto), amoxicilina con ácido clavulánico (sustancia), amoxicilina con ácido clavulánico, Amoxicilina-Ácido Clavulánico, Combinación Amoxicilina-Clavulanato de Potasio, Combinación Clavulanato de Potasio-Amoxicilina |
French |
Amoxi-clavulanate, Amoxicilline-acide clavulanique, Amox-clav, Amoxiclavulanate, Amoxycilline-acide clavulanique, Association amoxicilline-clavulanate de potassium, Co-amoxiclav, Coamoxiclav |
German |
Amoxicillin-Kaliumclavulanat-Kombination, Kaliumclavulanat-Amoxicillin-Kombination |
Portuguese |
Amoxicilina-Ácido Clavulânico, Combinação Amoxicilina-Clavulanato de Potássio, Combinação Clavulanato de Potássio-Amoxicilina |