IV. Medications

  1. Capsules: 300 mg
  2. Suspension: 125 to 250 mg/5ml

V. Dosing

  1. Adult (and age >13 years)
    1. Take 300 mg orally twice daily or 600 mg orally once daily
  2. Child (age <13 years old)
    1. Give 14 mg/kg/day divided once to twice daily
  3. Renal Dosing
    1. eGFR <30 ml/min
      1. Adult: Limit to 300 mg/day
      2. Child: Limit to 7 mg/kg/day (max 300 mg/day)
      3. Hemodialysis: Give renal dose after Dialysis every 48 hours

VI. Safety

  1. Pregnancy Category B
  2. Safe in Lactation

VII. Drug Interactions

  1. Iron (including Multivitamins with iron)
    1. Take Cefdinir at least 2 hours before or 2 hours after
  2. Antacids
    1. Take Cefdinir at least 2 hours before or 2 hours after

IX. References

  1. Hamilton (2020) Tarascon Pocket Pharmacopoeia
  2. (2012) Presc Lett, Resource #280706, Comparison of Cephalosporins

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Related Studies

Cost: Medications

cefdinir (on 12/21/2022 at Medicaid.Gov Survey of pharmacy drug pricing)
CEFDINIR 125 MG/5 ML SUSP Generic $0.15 per ml
CEFDINIR 250 MG/5 ML SUSP Generic $0.17 per ml
CEFDINIR 300 MG CAPSULE Generic $0.44 each

Ontology: cefdinir (C0060405)

Definition (NCI) A semi-synthetic cephalosporin and a beta-lactam antibiotic with bactericidal activity. Cefdinir's effect is dependent on its binding to penicillin-binding proteins (PBPs) located in the bacterial cytoplasmic membrane. Binding results in the inhibition of the transpeptidase enzymes, thereby preventing cross-linking of the pentaglycine bridge with the fourth residue of the pentapeptide and interrupting consequent synthesis of peptidoglycan chains. As a result, cefdinir inhibits bacterial septum and cell wall synthesis formation.
Concepts Antibiotic (T195) , Organic Chemical (T109)
MSH C056814
SnomedCT 108677001, 370366006
LNC LP19960-1, MTHU011339
English 7-(2 (2-aminothiazol-4-yl)-2-hydroxyiminoacetamido)-3-vinyl-3-cephem-4-carboxylic acid, cefdinir, CFDN, cefdinir (medication), CEFDINIR, cefdinir [Chemical/Ingredient], Cefdinir (substance), Cefdinir product (product), Cefdinir product, Cefdinir
Spanish producto con cefdinir (producto), cefdinir (producto), producto con cefdinir, cefdinir (sustancia), cefdinir

Ontology: Omnicef (C0285868)

Concepts Antibiotic (T195) , Organic Chemical (T109)
MSH C056814
English Omnicef, cefdinir (Omnicef), omnicef, Abbott brand of cefdinir