II. Updates: April 2025
-
Oral Mucosa Hyperpigmentation (derm, pigment)
- Updates
-
GLP1 Agonist (endo, pharm)
- Updates regarding gastrointestinal effects and Malnutrition risk
-
Insulinoma (endo, Hypoglycemia)
- Updates
-
Mastoiditis (ent, ear)
- Updates on Antibiotic management
-
Epistaxis (ent, nose)
- Updates with TXA related evidence
-
Hypothermia (er, environ)
- Updates regarding progressive EKG changes
-
Cardiopulmonary Resuscitation (er, exam)
- Updates regarding pulse checks
-
Trichloroethylene Poisoning (er, toxin)
- Added
-
Radiation Exposure (er, weapon)
- Updates
-
Central Retinal Artery Occlusion (eye, cv)
- Updates
-
Barrett Esophagus Cancer Risk Score (gi, exam)
- Added
-
Alcoholic Liver Disease (gi, liver)
- Updates
-
Bacterial Vaginosis (gyn, id)
- Updated with refractory/recurrence co-treatment of male sexual partner with Flagyl oral and Clindamycin Topical
- Thank you to Nate D for bringing a new article from NEJM to my attention
-
Chronic Pelvic Pain (gyn, sx)
- Updates
-
Paraneoplastic Syndrome (hemeonc, endo)
- Added
-
Sickle Cell Disease (hemeonc, Hemoglobin)
- Extensive updates including adding several subtopics
-
Blood Culture (id, lab)
- Updates
-
Mycobacteria (id, Bacteria)
- Updates
-
Mycoplasma (id, Bacteria)
- Updates to Mycoplasma pneumonia and Ureaplasma Urealyticum
-
Leprosy (id, Bacteria)
- Updates, including adding Clofazimine
-
Syphilis Serology (id, lab)
- Extensive updates including Treponemal Specific Test, Non-Treponemal Test and Dark-field Microscopy
-
Anti-Ribosomal Antibiotic (id, pharm)
- Updates to Macrolides, Tetracyclines, Aminoglycosides and other Anti-Ribosomal Antibiotics
-
Beta Lactams (id, pharm)
- Updates to Penicillins, Cephalosporins, Carbapenems and Aztreonam
-
Travel Preparation (id, travel)
- Updates to this and various related topics
-
Rabies (id, virus)
- Updates
-
Enzyme Activity (lab, exam)
- Added enzyme type image
-
Clofazimine (lung, pharm)
- Added
-
Acute Bronchitis (lung, rhonchi)
- Updates
-
Susceptible Tuberculosis Treatment (lung, tb)
- Updates to this and Active Tuberculosis related to the shorter 4 month course with Moxifloxacin
-
Down Syndrome (neuro, Disability)
- Updates
- Temporal Artery Biopsy (neuro, eye)
- Updates regarding Ultrasound
-
Vertebral Osteomyelitis (ortho, id)
- Updates
-
Wrist XRay (ortho, rad)
- Added Lateral XRay image
-
Pectoralis Major Muscle Rupture (ortho, Shoulder)
- Added
-
Pacifier (peds, behavior)
- Updates
-
Kratom (pharm, alternative)
- Added
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Suzetrigine (pharm, Analgesic)
- Added
-
Medication Patch (pharm, metabolism)
- Updates
-
Religious Fasting During Ramadan (pharm, nutrition)
- Updates
-
Trauma Informed Care (psych, anxiety)
- Added
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Prevention of Kidney Disease Progression (renal, prevent)
- Incorporated KDIGO 2024 recommendations
-
Interscalene Block (surgery, pharm)
- Updates
III. Updates: March 2025
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Atrial Fibrillation (cv, ekg)
- Updates
-
Mobitz II AV Block (cv, ekg)
- Updates
-
Vagal Maneuver (cv, procedure)
- Updates
-
POTS Syndrome (cv, exam)
- Updates regarding aerobic Exercise in its management
-
Genital Wart (derm, wart)
- Updates
-
Cat Scratch Disease (er, bite)
- Updates
-
Gastric Cancer (gi, hemeonc)
- Extensive updates
-
Helicobacter Pylori (gi, id)
- Updated H. pylori treatment again based on ACG 2024
-
Bowel Preparation (gi, procedure)
- Updates
-
Menorrhagia (gyn, Menses)
- Updates
-
Enoxaparin (hemeonc, pharm)
- Updates
-
Acinetobacter Baumannii (id, Bacteria)
- Added aerobic gram negative Nosocomial Infection
-
Brucellosis (id, Bacteria)
- Updates
-
Burkholderia Cepacia (id, Bacteria)
- Added aerobic gram negative Nosocomial Infection
-
Chlamydiaceae (id, Bacteria)
- Updates including to Trachoma, Inclusion Conjunctivitis, Chlamydial Urethritis, Psittacosis, TWAR
-
Pseudomonas Aeruginosa (id, Bacteria)
- Added
-
Q Fever (id, Bacteria)
- Updates
-
Rickettsiae (id, Bacteria)
- Updates to this and the associated diseases
-
Stenotrophomonas Maltophilia (id, Bacteria)
- Added aerobic gram negative Nosocomial Infection
-
Trench Fever (id, Bacteria)
- Added
-
Haemophilus Influenzae (id, Bacteria)
- Added, and updated Haemophilus Influenzae Pneumonia, Hib Vaccine
-
Yersinia Pestis (id, Bacteria)
- Updates
-
Francisella Tularensis (id, vector)
- Updates
-
Bordetella Pertussis (lung, Bacteria)
- Updates
-
Legionella (lung, Bacteria)
- Updates
-
First Seizure Evaluation (neuro, Seizure)
- Updates
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Status Epilepticus (neuro, Seizure)
- Updates
-
Growth Plate (ortho, anatomy)
- Updates
-
Plantar Fasciitis (ortho, foot)
- Updates
-
Epiphyseal Fracture (ortho, Fracture)
- Updates
-
Acute Osteomyelitis
- Updates (ortho, id)
-
Pediatric Leg Disorder (ortho, peds)
- Extensive updates including related topics (Intoeing, Out-toeing, Genu Valgum, Genu Varum)
-
Toxic Synovitis (ortho, peds)
- Updates
-
Sudden Infant Death Syndrome (peds, er)
- Updates
-
Alpha Lipoic Acid (pharm, alternative)
- Added
- Not recommended in Diabetic Neuropathy due to low efficacy
-
Refractory Depression Management (psych, depression)
- Psilocybin is slightly better than Placebo in Major Depression
-
Metabolic Acidosis (renal, acidbase)
- Updates
-
Metabolic Alkalosis (renal, acidbase)
- Updates
-
Arterial Blood Gas Interpretation (renal, lab)
- Updates
-
Suprapubic Bladder Aspiration (urology, procedure)
- Added
-
Phimosis (urology, penis)
- Updates regarding Topical Corticosteroid protocol
IV. Updates: February 2025
-
QTc Prolongation (cv, exam, ekg)
- Updates
-
Myocardial Infarction with Nonobstructive Coronary Arteries (cv, cad)
- Added
-
Cardiac Amyloidosis (cv, Myocardium)
- Added
-
Electrocardiogram in Children (cv, peds)
- Added
-
Clonidine Overdose (cv, pharm)
- Updates for the related Imidazoline Poisoning
-
Vasopressin (cv, pharm)
- Updates
-
Oral Health in Children (dental, prevent)
- Updates
-
Acute Sinusitis (ent, sinus)
- Updates
-
Copper Poisoning (er, toxin)
- Added
-
Seat Belt Sign (er, Trauma)
- Updates
-
Acute Vision Loss (eye, sx)
- Updates
-
Campylobacter jejuni (gi, id)
- Updates
-
Vibrio Cholerae (gi, id)
- Updates
-
Vibrio parahaemolyticus (gi, id)
- Added
-
Yersinia enterocolitica (gi, id)
- Updates
-
Pediatric Reflux (gi, peds)
- Updates
-
Sickle Cell Anemia (hemeonc, Hemoglobin)
- Updates to various associated topics
-
CVA Thrombolysis (hemeonc, pharm)
- TNK has low efficacy in minor stroke and is associated with increased CNS Hemorrhage risk
-
Andexxa (hemeonc, pharm)
- Updates on efficacy (does not alter patient-oriented outcomes and higher thrombosis risk)
-
Gram Negative Bacteria (id, Bacteria)
- Updates
-
Enterobacter (id, Bacteria)
- Added
-
Escherichia coli (id, Bacteria)
- Updates
-
Klebsiella Pneumoniae (id, Bacteria)
- Added
-
Proteus Mirabilis (id, Bacteria)
- Added
-
Salmonella (id, Bacteria)
- Updates
-
Serratia Marcescens (id, Bacteria)
- Added
-
Shigella (id, Bacteria)
- Updates
-
Yersinia Pestis (id, Bacteria)
- Updates
-
Meningococcal Vaccine (id, immunize)
- Updates
-
Sulopenem Etzadroxil and Probenecid (id, pharm)
- Added
-
Neisseria gonorrhoeae (id, std)
- Updates
-
Social Generation Category (manage, communication)
- Added
-
Meningococcal Meningitis (neuro, id)
- Updates
-
Carbidopa-Levodopa (neuro, pharm)
- Updates
-
Luxatio Erecta (ortho, Shoulder)
- Updates
-
Picky Eating (peds, behavior)
- Updates
-
Thumb Sucking (peds, behavior)
- Updates
-
Hyperimmune Bovine Colostrum (pharm, alternative)
- Added
-
Pediatric Insomnia (psych, peds, sleep)
- Updates
-
Factitious Disorder (psych, somatic)
- Updates
-
Dysuria (urology, sx)
- Updates
V. Updates: January 2025
-
Left Ventricular Outflow Obstruction (cv, chf)
- Updates
-
Pediatric Hypertension (cv, peds)
- Updates
-
Aprocitentan (cv, pharm)
- Added this Endothelin Receptor Antagonist, limited fourth line agent for Refractory Hypertension
- Requires REMS program enrollment to prescribe (Teratogenic)
-
Endothelin Receptor Antagonist (cv, pharm)
- Added this class used primarily for Pulmonary Arterial Hypertension
-
Exercise Stress Test (cv, procedure)
- Updated various stress tests
-
Subungual Melanoma (derm, hemeonc)
- Updates
-
Keloid (derm, hyperplasia)
- Updates to Keloid and Hypertrophic Scar
-
Cutaneous Sporotrichosis (derm, id)
- Updates
-
GLP-1 Agonist (endo, pharm)
- Added equivalent dosing for GLP-1 Agonists (to aid switching between agents)
-
Cardiopulmonary Resuscitation (er, exam)
- Updates regarding Pediatric Resuscitation
-
Listeria monocytogenes (gi, id)
- Updates
-
Liver Function Test Abnormality (gi, lab)
- Updates to this and related topics
-
Stress Ulcer (gi, pud)
- Updates regarding prophylaxis indications (need more than Mechanical Ventilation alone)
-
Premenstrual Disorder (gyn, psych)
- Updates
-
Direct Oral Anticoagulant Score (hemeonc, exam)
- Added
-
Sickle Cell Anemia (hemeonc, hgb)
- Updates regarding Penicillin prophylaxis
-
Pediatric Anemia (hemeonc, peds)
- Updates
-
Anthrax (id, Bacteria)
- Updates
-
Bacillus Cereus (id, Bacteria)
- Added
-
Coryneform Bacteria (id, Bacteria)
- Added
-
Corynebacterium diphtheriae (id, Bacteria)
- Updates
- Clostridium (id, Bacteria)
-
Rhodococcus equi (id, Bacteria)
- Added
-
Streptococcus (id, Bacteria)
- Updates to Streptococcus, Group A Streptococcus, Group B Streptococcus
- Added Streptococcus Viridans Group
-
Staphylococcus (id, Bacteria)
- Updates to Staphylococcus Aureus and MRSA
- Added Staphylococcus Epidermidis, Staphylococcus Saprophyticus
-
Pneumococcal Conjugate Vaccine (id, immunize)
- Significant updates that simplify overall Pneumococcal Vaccine protocols
- All adults age 50 years and older are now vaccinated with 1 dose of PCV20 or PCV21
- Immunocompromised Adults age 18 to 50 years are also vaccinated with PCV20 or PCV21
- Children are still vaccinated with Primary Series with PCV20 until PCV21 is approved
-
Quinine Toxicity (id, pharm)
- Added
-
Advanced Airway in Children (lung, procedure)
- Updated failed airway in age <8 years: surgical Tracheostomy vs Needle Cricothyrotomy
-
Cerebral Intraparenchymal Hemorrhage (neuro, cv)
- Updates
-
Subarachnoid Hemorrhage (neuro, cv)
- Updates
-
Duke Abdominal Assessment Scale (nicu, exam)
- Added as part of NEC evaluation
-
Stress Fracture (ortho, Fracture)
- Updates
-
Reverse Total Shoulder Arthroplasty (ortho, surgery)
- Updates
-
Peppermint Oil (pharm, alternative)
- Updates
-
Alcohol Withdrawal (psych, cd)
- Updates
-
Septic Joint (rheum, id)
- Updates
-
Pediatric Abdominal Pain (surgery, peds)
- Updates
-
Priapism (urology, penis)
- Correction in Phenylephrine preparation, thanks to Nick Yarbrough, Emergency PharmD