II. Pathophysiology

  1. Non-motile, non-spore forming rod-shaped (or pleiomorphic) Bacteria
    1. Corynebacterium is derived from Greek (Koryne=Club, Bacterion=Little Rod)
    2. May be aerobic or anaerobic

III. Types

  1. Corynebacterium diphtheriae (Diphtheria)
  2. Coryneform Bacteria (Diphtheroids)
    1. Includes multiple genera in addition to Corynebacterium (e.g. Arcanobacterium, Brevibacterium, Microbacterium)
    2. Colonize human skin as well as soil and water
    3. Frequently found in contaminated cultures in hospitalized patients
    4. Community acquired infections
      1. Urinary Tract Infections
      2. Prostatitis
      3. Endocarditis
      4. Erythrasma (Corynebacterium minutissimum)
    5. Nosocomial Infections
      1. Sites
        1. Surgical Wound Infections
        2. Catheter infections
        3. Endocarditis
      2. Organisms
        1. Corynebacterium jeikeium
        2. Corynebacterium urealyticum
        3. Corynebacterium striatum

IV. References

  1. Gladwin, Trattler and Mahan (2014) Clinical Microbiology, Medmaster, Fl, p. 58-9
  2. Bernard (2012) J Clin Microbiol 50(10):3152-8 +PMID: 22837327 [PubMed]

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Related Studies

Ontology: Corynebacterium (C0010148)

Definition (NCI_CDISC) Any bacteria that is not assigned to the species level but can be assigned to the Corynebacterium genus level.
Definition (NCI) A genus of Gram-positive, aerobic or facultatively anaerobic, non-motile, non-sporulated, rod-shaped Actinobacteria. Most are a part of normal skin flora.
Definition (MSH) A genus of asporogenous bacteria that is widely distributed in nature. Its organisms appear as straight to slightly curved rods and are known to be human and animal parasites and pathogens.
Definition (CSP) genus of asporogenous bacteria that is widely distributed in nature; appear as straight to slightly curved rods and are known to be human and animal parasites and pathogens.
Concepts Bacterium (T007)
MSH D003352
SnomedCT 77086004
English Genus Corynebacterium (organism), Corynebacterium (organism), CORYNEBACT, Corynebacterium, corynebacterium, Caseobacter Crombach 1978, Corynebacterium Lehmann and Neumann 1896 (Approved Lists 1980) emend. Bernard et al. 2010, CORYNEBACTERIUM, Corynebacterium, NOS, Genus Corynebacterium
Swedish Corynebacterium
Spanish Corynebacterium (organismo), género Corynebacterium (organismo), Corynebacterium, género Corynebacterium
Czech Corynebacterium
Finnish Korynebakteeri
Russian KORINEBAKTERII, КОРИНЕБАКТЕРИИ
French Corynébactérie, Corynebacterium
Polish Maczugowce, Corynebacterium
Norwegian Corynebacterium
German Corynebacterium
Italian Corynebacterium
Dutch Corynebacterium
Portuguese Corynebacterium

Ontology: Diphtheroids (C0302285)

Concepts Bacterium (T007)
SnomedCT 54642001
English diphtheroids, diphtheroid, Diphtheroids, Diphtheroids (organism)
Spanish difteroides (organismo), difteroides

Ontology: Corynebacterium striatum (C0315183)

Definition (NCI) A species of aerobic or facultatively anaerobic, Gram-positive, coryneform, pleomorphic bacilli assigned to the phylum Actinobacteria. This species is nonmotile, non-spore forming, catalase positive, urease negative, pyrazinamidase positive, reduces nitrate, ferments glucose and sucrose, non-lipophilic, indole negative, and hydrolyzes gelatin. C. striatum is commensal in the skin and nasal flora and is a pathogen known to cause bacteremia in immunocompromised patients with respiratory infections, skin ulcers, or during surgery.
Definition (NCI_CDISC) Any bacterial organism that can be assigned to the species Corynebacterium striatum.
Concepts Bacterium (T007)
SnomedCT 63815007
English Bacterium striatum, Corynebacterium striatum (Chester 1901) Eberson 1918, CORYNEBACTERIUM STRIATUM, Corynebacterium striatum, Corynebacterium flavidum, Corynebacterium striatum (organism)
Spanish Corynebacterium striatum (organismo), Corynebacterium striatum

Ontology: Corynebacterium jeikeium (C0315194)

Definition (NCI_CDISC) Any bacterial organism that can be assigned to the species Corynebacterium jeikeium.
Definition (NCI) A species of bacteria in the phylum Actinobacteria consisting of lipophilic, non-spore-forming, non-motile, Gram-positive rods that vary from short coccobacilli to long bacillary forms.
Concepts Bacterium (T007)
SnomedCT 63410006
English Corynebacterium Group JK, CDC Group JK, CDC coryneform group JK, Corynebacterium jeikeium Jackman et al. 1988, CORYNEBACTERIUM JEIKEIUM, CDC GROUP JK, CORYNEBACTERIUM GROUP JK, Corynebacterium jeikeium, Corynebacterium, group JK, CDC Corynebacterium group JK, JK - Corynebacterium jeikeium, Corynebacterium jeikeium (organism)
Spanish Corynebacterium jeikeium (organismo), Corynebacterium jeikeium - JK, Corynebacterium, grupo JK del CDC, Corynebacterium, grupo JK, Corynebacterium jeikeium

Ontology: Corynebacterium urealyticum (C0445704)

Definition (NCI_CDISC) Any bacterial organism that can be assigned to the species Corynebacterium urealyticum.
Definition (NCI) A species of aerobic or facultatively anaerobic, Gram-positive, coryneform, pleomorphic bacilli assigned to the phylum Actinobacteria. This species is nonmotile, non-spore forming, catalase positive, oxidase negative, pyrazinamidase positive, does not reduce nitrate, lipophilic, does not hydrolyze esculin or gelatin, and does not ferment glucose, maltose, or sucrose. C. urealyticum is commensal to the human skin and is known to cause urinary tract infections, kidney stones and pneumonia.
Concepts Bacterium (T007)
SnomedCT 113613004
English CDC Group D2, Corynebacterium Group D-2, CDC coryneform group D-2, Corynebacterium ureailyticum, CORYNEBACTERIUM UREALYTICUM, CDC GROUP D2, CORYNEBACTERIUM GROUP D-2, Corynebacterium urealyticum Pitcher et al. 1992, CDC Corynebacterium group D-2, Corynebacterium urealyticum, Corynebacterium urealyticum (organism)
Spanish Corynebacterium grupo D-2 del CDC, Corynebacterium urealyticum (organismo), Corynebacterium urealyticum

Ontology: Coryneform bacteria (C0995681)

Definition (CSP) gram-positive, primarily aerobic bacteria that occur as irregularly shaped rods and tend to form branching filaments.
Concepts Bacterium (T007)
SnomedCT 116442009
English coryneform bacteria, Coryneform bacteria, coryneform bacterium, Coryneform bacteria (organism)
Spanish bacterias corineiformes (organismo), bacterias corineiformes, corinebacterias