II. Signs
- No clinical signs of Syphilis (CSF Normal)
III. Types
- Early Latency (First year after infection)
- Symptoms present in 25% of early Latent Syphilis and this group will transmit Syphilis sexually
- Late Latency (Latent infection >1 year, typically 3-20 years)
- No symptoms of primary or Secondary Syphilis
- Typically only infectious in pregnancy and transfusion
IV. Labs
- See Syphilis Testing
- Only Syphilis Serology positive during Latent Syphilis
V. Management
- See Syphilis
VI. Course
- Progression to Tertiary Syphilis in one third of untreated patients
VII. References
- Green, Cohen, Billington (2016) Crit Dec Emerg Med 30(11): 4-10
- Kirk, McHugh and Parnell (2023) Crit Dec Emerg Med 37(8): 23-9
- Mattel (2012) Am Fam Physician 86(5): 433-40 [PubMed]
- Ricco (2020) Am Fam Physician 102(2): 91-8 [PubMed]