II. Signs

  1. No clinical signs of Syphilis (CSF Normal)

III. Types

  1. Early Latency (First year after infection)
    1. Symptoms present in 25% of early Latent Syphilis and this group will transmit Syphilis sexually
  2. Late Latency (Latent infection >1 year, typically 3-20 years)
    1. No symptoms of primary or Secondary Syphilis
    2. Typically only infectious in pregnancy and transfusion

IV. Labs

  1. See Syphilis Testing
  2. Only Syphilis Serology positive during Latent Syphilis

V. Management

  1. See Syphilis

VI. Course

  1. Progression to Tertiary Syphilis in one third of untreated patients

VII. References

  1. Green, Cohen, Billington (2016) Crit Dec Emerg Med 30(11): 4-10
  2. Kirk, McHugh and Parnell (2023) Crit Dec Emerg Med 37(8): 23-9
  3. Mattel (2012) Am Fam Physician 86(5): 433-40 [PubMed]
  4. Ricco (2020) Am Fam Physician 102(2): 91-8 [PubMed]

Images: Related links to external sites (from Bing)

Related Studies

Ontology: Syphilis, Latent (C0039133)

Definition (NCI) A stage of syphilis characterized by the serologic evidence of infection by Treponema pallidum without evidence of accompanying signs or symptoms related to the disease.
Concepts Disease or Syndrome (T047)
MSH D013592
ICD9 097.1
ICD10 A53.0
SnomedCT 444150000, 186906003
English Syphilis, Latent, Latent syphilis unspecified, Latent syphilis, unspecified as early or late, latent syphilis (diagnosis), latent syphilis, Latent syphilis, Latent syphilis (disorder), Latent syphilis NOS, Syphilis, Latent [Disease/Finding], Latent Stage Syphili, Syphilis, Latent Stage, Latent Stage Syphilis, Syphili, Latent Stage, Latent syphilis, unspecified, syphilis latent, Latent syphilis unspecified (disorder), latent; syphilitic, syphilis; latent, Latent Syphilis
Swedish Syfilis, latent
Czech syfilis latentní, Latentní syfilis, Latentní syfilis, blíže neurčená
Finnish Piilevä kuppa
Russian SIFILIS LATENTNYI, СИФИЛИС ЛАТЕНТНЫЙ
German Latente Syphilis, nicht als frueh oder spaet bezeichnet, Latente Syphilis, latente Syphilis, unspezifisch, Lues, latente, Syphilis, latente, Lues latens
Korean 조기인지 만기인지 상세불명의 잠복성 매독
Spanish sífilis latente (trastorno), sífilis latente, Sífilis latente, Sífilis latente no especificada, sífilis latente no especificada, sífilis latente no especificada (trastorno), Sífilis Latente
Dutch latente syfilis, niet-gespecificeerd, latente syfilis, latent; syfilis, syfilis; latent, Latente syfilis, niet gespecificeerd als vroeg of laat, Latente syfilis, Syfilis, latente
Portuguese Sífilis latente NE, Sífilis latente, Sífilis Latente
Italian Sifilide latente non specificata, Sifilide latente
French Syphilis latente, non précisée, Syphilis latente, Syphilis occulte, Syphilis sérologique, Syphilis sérologique cliniquement latente
Japanese 潜伏梅毒, 潜伏梅毒、詳細不明, センプクバイドクショウサイフメイ, センプクバイドク
Polish Kiła utajona
Hungarian Latens syphilis, nem meghatározott, Latens syphilis
Norwegian Latent syfilis