II. Findings
III. Management: Pregnancy (> 36 weeks gestation)
- Treat primary HSV II infections on Primary Genital Herpes protocol
- Culture Cervix and lesion every 3-5 days until negative
-
Acyclovir if indicated
- See below for prevention of Neonatal HSV transmission
- Cesarean Section indications
IV. Complications: Vertical transmission
V. Prevention: Neonatal Herpes Simplex Virus transmission
- Prevent transmission from HSV positive partner
- Abstinence or Condom use during pregnancy
- Consider Vaccine below
- Antiviral prophylaxis for HSV positive partner
- Avoid oral-genital contact if Oral HSV in partner
- Vaccinations as of yet are experimental (e.g. HSV-2 Glycoprotein-D-Adjuvant Vaccine)
- Identify HSV II risks in all pregnant women
- Personal history of HSV II
- Partners with HSV II
- Screen at first Prenatal Visit and perinatally
- Cesarean Section for all women with active lesions
-
Acyclovir
-
Acyclovir 400 mg orally twice daily from 36 weeks until delivery
- Indicated in all pregnant women with Genital Herpes history
- Also treat any Primary Genital Herpes outbreak during pregnancy
- Also treat all women with near-term or perinatal Genital Herpes outbreak
-
Acyclovir 400 mg orally twice daily from 36 weeks until delivery
- References
