II. Symptoms: Prodrome (precedes genital lesions by hours to days)
- Genital symptoms
- Focal, genital pain, Paresthesias, burning, itching
- Lesions occur at the perineum, buttock, upper thigh or perianal area
- Systemic symptoms
III. Signs: Skin Lesions
IV. Signs: Adenopathy
- Starts during second or third week of disease
- Usually bilateral inguinal adenopathy
- Slightly enlarged, mildly tender
V. Course
- Viral shedding: 15-16 days
- Complete lesion healing: 19-21 days
VI. Diagnosis
- See HSV Test
VII. Management
- See Genital Herpes in Pregnancy
- See Genital Herpes
- Outpatient
- General
- Shortens duration of pain and period of viral shedding
- May extend Antiviral course beyond 10 days if incomplete healing
- Acyclovir
- Famciclovir 250 mg orally three times daily for 7-10 days
- Valacyclovir 1000 mg orally twice daily for 7-10 days
- General
- Inpatient
- Indications: Severe or complicated Herpes Simplex Virus Infection
- HSV-related hepatitis
- HSV Encephalitis
- HSV pneumonitis
- First-Line
- Acyclovir 5-10 mg/kg IV every 8h for 5 to 7 days
- Convert to oral agents when able
- Second-Line: Acyclovir resistant cases
- Indications: Severe or complicated Herpes Simplex Virus Infection
VIII. Complications
- See Genital Herpes
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Related Studies
Concepts | Disease or Syndrome (T047) |
SnomedCT | 402888002 |
English | herpes simplex genitalis primary, primary herpes simplex genitalis (diagnosis), primary herpes simplex genitalis, Primary herpes genitalis, Primary herpes simplex infection of genitalia (disorder), Primary herpes simplex infection of genitalia |
Spanish | infección primaria de genitales por herpes simplex (trastorno), infección primaria de genitales por herpes simplex |