II. Definitions

  1. Paresthesia
    1. Abnormal skin Sensation (e.g. tingling, burning, pricking) not caused by an outside stimulus

III. Symptoms

  1. Abnormal Sensations in the absence of stimuli
    1. Numb Sensation
    2. Cold, warmth or burning Sensation
    3. Prickling, tingling or pins and needles Sensation
    4. Skin crawling Sensation
    5. Pruritus
  2. Location
    1. Extremities

IV. Differential Diagnosis

V. Labs: Initial Evaluation

  1. Complete Blood Count
  2. Chemistry panel or metabolic panel (Chem7)
  3. Urinalysis
  4. Thyroid Stimulating Hormone (TSH)
  5. Erythrocyte Sedimentation Rate (ESR)

VI. Labs: Other Studies when indicated

  1. Serum Folate
  2. Vitamin B12
  3. Syphilis Serology (VDRL or RPR)
  4. Antinuclear Antibody (ANA)
  5. Nerve Conduction velocities
  6. Electromyogram (EMG)
  7. XRay of affected extremity
  8. CT Head or MRI Head
  9. Myelography
  10. Nerve biopsy
  11. Muscle biopsy
  12. Serum Immunoelectrophoresis
  13. Purified Protein Derivative (PPD)

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