II. Background

  1. Extract from chrysanthemums
  2. Pyrethroids are longer acting derivatives (Permethrin)
  3. Pesticide Agents related to Pyrethrins
    1. Allethrin
    2. Cyfluthrin
    3. Cypermethrin
    4. Deltamethrin
    5. Dimethrin
    6. Fenothrin
    7. Fenvalerate
    8. Permethrin
    9. Remethrin

III. Indications

IV. Advantages

  1. Available without a prescription
  2. Convenient (only 10 minute application)

V. Disadvantages

  1. Does not kill all unhatched eggs
  2. Requires repeat application in 5-7 days
  3. Treatment failures are common

VI. Directions for treatment of Lice

  1. Apply Shampoo to involved area
  2. Wash after 10 minutes
  3. Reapply Shampoo in 5-7 days

VII. Preparations

  1. Bottles of 60, 120, 240 ml

VIII. Adverse Effects

  1. Mechanism
    1. Nerve toxicity is rare in humans
    2. Minimal absorption and rapid hepatic metabolism
  2. Effects
    1. Allergic Reaction in 1-3%
      1. Nasal congestion
      2. Asthma exascerbation
    2. Topical effects
      1. Paresthesias (hands and face)
    3. Rare neurologic effects
      1. Seizures
      2. Tremor
      3. Incoordination

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Related Studies

Ontology: Pyrethrins (C0034245)

Definition (MSH) The active insecticidal constituent of CHRYSANTHEMUM CINERARIIFOLIUM flowers. Pyrethrin I is the pyretholone ester of chrysanthemummonocarboxylic acid and pyrethrin II is the pyretholone ester of chrysanthemumdicarboxylic acid monomethyl ester.
Concepts Hazardous or Poisonous Substance (T131) , Organic Chemical (T109)
MSH D011722
SnomedCT 23178000, 400602009, 45620004
English Pyrethrins, pediculicides pyrethrins, pyrethrins (medication), pyrethrins, Pyrethrins [Chemical/Ingredient], pyrethrin, Pyrethrins (substance), Pyrethrin, Pyrethrin (product), Pyrethrin (substance), Pyrethrins, NOS, PYRETHRINS
Swedish Pyretriner
Czech pyrethriny
Finnish Pyretriinit
Polish Pyretryny
Japanese ピレスリン, ピレトリン
French Pyréthrines
Spanish piretrinas (sustancia), piretrinas, piretrina (producto), piretrina (sustancia), piretrina, Piretrinas
German Pyrethrine
Italian Piretrine
Portuguese Piretrinas

Ontology: RID (C0073361)

Concepts Pharmacologic Substance (T121) , Organic Chemical (T109)
MSH C027982
English RID, Rid Pediculicide, rid pediculicide product, rid