III. Indications
- Stubborn periungual warts
- Molluscum Contagiosum in children
IV. Medications
- Background
- Until YCanth was released in 2023, Cantharidin was no longer available is U.S., but available in Canada
- Cantharidin (Cantharone, Canthacur)
- Canthacur PS (w/ Podophyllin 5% + Salicylic Acid 30%)
- Reserve for Plantar Warts due to irritation
- YCanth
- Single use applicator of Cantharidin FDA approved for age >2 years (in 2023, approaches $700/applicator)
- Applied by medical provider every 3 weeks for 4 visits
- Clearance of molluscum in 3 months (NNT 3)
- (2023) Presc Lett 30(10): 58-9
V. Precautions
- Apply ONLY in office
- Avoid touching normal skin
VI. Technique: Cantharidin Application
- Instructions apply to the original Cantharidin
- YCanth has specific instructions (see DailyMed link below)
- Allow liquid to dry over wart
- Then cover with occlusive tape (e.g. Blenderm)
- Remove tape after 24 hours
- Remove earlier for significant discomfort
- In 2-3 days remove Blister under Local Anesthesia
- Snip off near base OR Curette
- Benefits of removing Blister
- Prevents progression to ring wart
- Prevents recurrence
VII. Follow-up
- Consider repeat treatment weekly as tolerated