Cantharidin

Aka: Cantharidin

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II. Mechanism

  1. Vesicant obtained from Blister beetle

III. Indications

  1. Stubborn periungual warts
  2. May be useful in Molluscum Contagiosum in children

IV. Obtaining

  1. No longer available is U.S., but available in Canada
  2. Manufactured by Omniderm
    1. Phone: 1-888-458-0158
    2. Fax: 1-514-458-1477

V. Preparations

  1. Cantharidin (Cantharone, Canthacur)
  2. Canthacur PS (w/ Podophyllin 5% + Salicylic Acid 30%)
    1. Reserve for Plantar Warts due to irritation

VI. Precautions

  1. Apply ONLY in office
  2. Avoid touching normal skin

VII. Application

  1. Allow liquid to dry over wart
  2. Then cover with occlusive tape (e.g. Blenderm)
  3. Remove tape after 24 hours
    1. Remove earlier for significant discomfort
  4. In 2-3 days remove Blister under Local Anesthesia
    1. Snip off near base OR Curette
    2. Benefits of removing Blister
      1. Prevents progression to ring wart
      2. Prevents recurrence

VIII. Follow-up

  1. Consider repeat treatment weekly as tolerated

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