II. Precautions
- Do not use in infants
- Much greater risk of toxicity than with other agents
- Percutaneous absorption 10-20 fold over Permethrin
- Serum levels are 40 fold higher than Permethrin
- CNS toxicity 2-4 fold over Permethrin
- Seizure risk in epileptics and children
III. Mechanism
- Organochlorine similar to DDT
- Organochlorine Agents
- Chlorobenzilate
- Dicofol
- Dienochlor
- Endosulfan
- Lindane
V. Preparation
- Lindane 1% Shampoo (60 ml)
- Lindane 1% Lotion (60 ml)
VI. Directions for use
VII. Adverse Effects
- Mechanism
- Disrupts axonal Sodium and Potassium flow
- Affects both central and Peripheral Nerves
- Higher toxicity in broken skin and young children
- Effects: Neurotoxicity
- Management of toxicitiy
- Skin Decontamination
- ABC Management
- Seizure control with Diazepam
- Intravenous Fluids (D5W) with Thiamine