II. Indications
- Dermatophyte Infection (Tinea Corporis)
- Cutaneous Candidiasis
- Tinea Versicolor
III. Preparations
- Cutaneous dermatophytes: Ciclopirox olamine 1% (Loprox)
- Onychomycosis: Ciclopirox 8% lacquer (Penlac)
IV. Mechanism: Broad-spectrum activity
- Antifungal for dermatophytes and yeast
- Some antibacterial activity in vitro
V. Efficacy
-
Tinea Pedis (Loprox)
- More effective than OTC Clotrimazole (Lotrimin)
-
Onychomycosis (Penlac)
- NOT recommended
- Requires 48 week application
- Minimally better than Placebo for cure rates
- Partial clearance rates are also poor
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Related Studies
| ciclopirox (on 10/19/2022 at Medicaid.Gov Survey of pharmacy drug pricing) | ||
| CICLOPIROX 0.77% CREAM | Generic | $0.21 per gram |
| CICLOPIROX 0.77% GEL | Generic | $0.70 per gram |
| CICLOPIROX 0.77% TOPICAL SUSP | Generic | $0.90 per ml |
| CICLOPIROX 1% SHAMPOO | Generic | $0.36 per ml |
| CICLOPIROX 8% SOLUTION | Generic | $1.70 per ml |