II. Indications
- Hirsutism: Removal of unwanted facial hair in women
III. Pharmacology
- Irreversible inhibitor of Ornithine decarboxylase
- Inhibits polyamine biosynthesis
- Decreases polyamine mediated cell division
- Prior systemic use for African Trypanosomiasis
- Peak systemic absorption <10 ng/ml
IV. Adverse Effects: Local irritation
- Stinging or burning
- Tingling
V. Dosing (30 gram tube costs pharmacist $42)
- Apply thin layer to affected area bid
- Doses should be at least 8 hours apart
- Avoid washing area for 4 hours after application
VI. Efficacy
- Modestly effective in reducing unwanted facial hair
- Hair Growth recurs soon after stopping medication
VII. References
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Related Studies
| vaniqa (on 5/18/2022 at Medicaid.Gov Survey of pharmacy drug pricing) | ||
| VANIQA 13.9% CREAM | $3.53 per gram | |