II. Indication
III. Mechanism
- Topical antibacterial, Keratolytic agent
IV. Efficacy
- Not as effective as originally thought
- Only mild effect
- Use as an adjunct to other treatment
V. Dosing
- Apply twice daily
- Cream 20% (Azelex)
- Approved for Acne Vulgaris
- Gel 15% (Finacea)
- Approved for Acne Rosacea
- Much better Bioavailability than Azelex
VI. Adverse Effects
- Hypopigmentation
- Less irritating than Tretinoin or Benzoyl Peroxide
- Pruritus
- Burning, stinging and tingling
- Local erythema
VII. Precautions
- Use caution in Acne Vulgaris patients with dark skin
- May cause Hypopigmentation
VIII. Safety
- Pregnancy Category B
- Only category B Keratolytic agent
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azelaic acid (on 12/21/2022 at Medicaid.Gov Survey of pharmacy drug pricing) | ||
AZELAIC ACID 15% GEL | Generic | $0.85 per gram |