Medication Causes of Hyperandrogenism

Aka: Medication Causes of Hyperandrogenism, Medication Causes of Hirsutism, Medication Causes of Hypertrichosis, Hirsutism due to Medication, Hypertrichosis due to Medication, Hyperandrogenism due to Medication

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II. Causes: Hypertrichosis (non-androgen related)

  1. Cyclosporine - common
  2. Acitretin (Soriatane)
  3. Azelaic Acid (Finacea)
  4. Cetirizine (Zyrtec)
  5. Citalopram (Celexa)
  6. Topical Corticosteroids
  7. Diazoxide
  8. Etonogestrel Implant (Implanon)
  9. Penicillamine
  10. Phenytoin (Dylantin)
  11. Streptomycin
  12. Minoxidil

III. Causes: Hirsutism (related to excessive androgen exposure)

  1. Endocrine agents
    1. Systemic Corticosteroids
    2. Sex Hormones
      1. Anabolic Steroids
      2. Danazol (Danocrine)
      3. Testosterone
      4. Estrogens
      5. Leuprolide (Lupron)
      6. Progestins
    3. Oral Contraceptives: High Progestin Androgenic Activity
      1. Levonorgestrel (Nordette, Alesse, Triphasil)
      2. Norethindrone (Loestrin, Estrostep, Ortho Novum 1/35)
      3. Norgestrel (e.g. Ovral, Lo-Ovral, Ovrette)
  2. Chemotherapeutic and Immunosuppressant agents
    1. Cyclosporine
    2. Interferon alfa
    3. Mycophenolate (Cellcept)
    4. Tacrolimus (Prograf)
  3. Cardiovascular agents
    1. Reserpine (Serpasil)
    2. Methyldopa (Aldomet)
  4. Dermatologic agents
    1. Isoretinoin (Accutane)
  5. Gastrointestinal agents
    1. Metoclopramide (Reglan)
    2. Phenothiazines
  6. Psychiatric agents
    1. Aripiprazole (Abilify)
    2. Bupropion (Wellbutrin)
    3. Clonazepam (Klonopin)
    4. Eszopiclone (Lunesta)
    5. Fluoxetine (Prozac)
    6. Olanzapine (Zyprexa)
    7. Paroxetine (Paxil)
    8. Trazodone
    9. Venlafaxine (Effexor)
  7. Neurologic Agents
    1. Carbamazepine (Tegretol)
    2. Lamotrigine (Lamictal)
    3. Dantrolene
    4. Diazoxide
    5. Pregabalin (Lyrica)
    6. Selegeline (Eldepryl)
    7. Tiagabine (Gabitril)
    8. Valproic Acid
    9. Zonisamide (Zonegran)
  8. Ophthalmologic Agents
    1. Bimatoprost (Lumigan)

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