II. Preparations (Norethindrone / Ethinyl Estradiol)
- Biphasics
- Ortho-Novum 10/11 or Necon 10/11 (0.5 - 1.0 / 35)
- BiNovum (UK, 0.5 - 1.0 / 35)
- Triphasics
- Ortho-Novum 7/7/7, Necon 7/7/7 or Nortrel 777 (0.5 - 0.75 - 1.0 / 35)
- TriNovum (UK, 0.5 - 0.75 - 1.0 / 35)
- Tri-Norinyl or Leena (0.5 - 1.0 - 0.5 / 35)
- Synphase (UK, 0.5 - 1.0 - 0.5 / 35)
III. Components
- Norethindrone 0.5 to 1.0 (see preparations above)
- Ethinyl Estradiol 35 ug
IV. Effect
- Relative Progestational Activity: 0.8 (moderate)
- Estrogenic Activity: 48 (high)
- Androgenic Activity: 0.25 (moderate)
V. Pill associated problems
- Indications to switch to Ortho Cyclen
- Acne Vulgaris (lower androgen)
- Increased Appetite (lower Progestin)
- Major Depression provoked (lower Progestin)
- Indications to switch to Demulen 1/35
- Breast Tenderness or engorgement (lower Estrogen)
- Break-through bleed days 10-21 (more Progestin)
- Headaches (lower Estrogen)
- Heavy Menses (more Progestin or less Estrogen)
- Dysmenorrhea or Menstrual Cramps (more Progestin)
- Moodiness (less Estrogen or more Progestin)
- Weight gain (less Estrogen or more Progestin)
- Indications to switch to Modicon
- Indications to switch to Nordette
- Libido decreased (more androgen)
VI. References
- Cerel-Suhl (1999) Am Fam Physician 60(7):2073 [PubMed]
- Speroff (1993) Obstet Gynecol 81:1034-47 [PubMed]
- Dickey (1998) Managing Contraceptive Pill Patients
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