First Generation Progestin

Aka: First Generation Progestin, Norethindrone, Norethynodrel

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II. Class

  1. 19 Nor-TestosteroneProgestin: Estrane

III. Norethindrone

  1. Relative Progestational Activity: 1.0
    1. Estrogenic Activity: 1.0
    2. Androgenic Activity: 1.0
    3. Endometrial Activity: 1.0
    4. Anti-Estrogen: Active
  2. Preparations
    1. Ethinyl Estradiol
      1. Brevicon or Modicon (0.5/35)
      2. Ovcon (0.4/35, 1/50)
      3. Norinyl or Ortho-Novum 1/35
      4. Ortho-Novum 10/11 Biphasic (0.5-1.0/35)
      5. Ortho-Novum 7/7/7 Triphasic (0.5-0.75-1.0/35)
      6. Tri-Norinyl Triphasic (0.5-1.0-0.5/35)
    2. Mestranol (50 mcg is equivalent to 35 mcg Estradiol, 1 mcg Norethindrone)
      1. Norinyl 1/50
      2. Ortho-Novum 1/50
      3. Necon 1/50
      4. Norinyl-1 (UK)
    3. Progestin-only (Mini-Pill)
      1. Micronor, Nor-QD (0.35)

IV. Norethynodrel

  1. Relative Progestational Activity: 0.3
    1. Estrogenic Activity: 8.3
    2. Androgenic Activity: 0
    3. Endometrial Activity: 0
    4. Anti-Estrogen: Inactive
  2. Preparations (MestranolEstrogen component)
    1. Enovid 5 (5/75)
    2. Enovid E (2.5/100)

V. References

  1. Cerel-Suhl (1999) Am Fam Physician 60(7):2073 [PubMed]
  2. Speroff (1993) Obstet Gynecol 81:1034-47 [PubMed]
  3. Dickey (1998) Managing Contraceptive Pill Patients

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Related Studies

Cost: Medications

norethindrone (on 12/21/2022 at Medicaid.Gov Survey of pharmacy drug pricing)
NORETHINDRONE 0.35 MG TABLET Generic $0.15 each
NORETHINDRONE 5 MG TABLET Generic $0.31 each
FPNotebook does not benefit financially from showing this medication data or their pharmacy links. This information is provided only to help medical providers and their patients see relative costs. Insurance plans negotiate lower medication prices with suppliers. Prices shown here are out of pocket, non-negotiated rates. See Needy Meds for financial assistance information. GoodRx is another tool for finding lower drug prices.

Related Topics in Pharmacology

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