II. Class

  1. 19 Nor-TestosteroneProgestin: Estrane

III. Norethindrone

  1. Relative Progestational Activity: 1.0
    1. Estrogenic Activity: 1.0
    2. Androgenic Activity: 1.0
    3. Endometrial Activity: 1.0
    4. Anti-Estrogen: Active
  2. Preparations
    1. Ethinyl Estradiol
      1. Brevicon or Modicon (0.5/35)
      2. Ovcon (0.4/35, 1/50)
      3. Norinyl or Ortho-Novum 1/35
      4. Ortho-Novum 10/11 Biphasic (0.5-1.0/35)
      5. Ortho-Novum 7/7/7 Triphasic (0.5-0.75-1.0/35)
      6. Tri-Norinyl Triphasic (0.5-1.0-0.5/35)
    2. Mestranol (50 mcg is equivalent to 35 mcg Estradiol, 1 mcg Norethindrone)
      1. Norinyl 1/50
      2. Ortho-Novum 1/50
      3. Necon 1/50
      4. Norinyl-1 (UK)
    3. Progestin-only (Mini-Pill)
      1. Micronor, Nor-QD (0.35)

IV. Norethynodrel

  1. Relative Progestational Activity: 0.3
    1. Estrogenic Activity: 8.3
    2. Androgenic Activity: 0
    3. Endometrial Activity: 0
    4. Anti-Estrogen: Inactive
  2. Preparations (MestranolEstrogen component)
    1. Enovid 5 (5/75)
    2. Enovid E (2.5/100)

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Related Studies

Cost: Medications

norethindrone (on 12/21/2022 at Medicaid.Gov Survey of pharmacy drug pricing)
NORETHINDRONE 0.35 MG TABLET Generic $0.15 each
NORETHINDRONE 5 MG TABLET Generic $0.31 each

Ontology: Norethindrone (C0028356)

Definition (NCI) A synthetic progestational substance with some anabolic, estrogenic, and androgenic properties. Norethindrone binds to the progesterone intracellular receptors in the reproductive system and the resultant activated complex interacts with specific DNA sites. This leads to an alteration in protein synthesis and results in an inhibition of LH release. Consequently, it inhibits ovulation and changes the normal cycle of cervical mucus and endometrium.
Definition (MSH) A synthetic progestational hormone with actions similar to those of PROGESTERONE but functioning as a more potent inhibitor of ovulation. It has weak estrogenic and androgenic properties. The hormone has been used in treating amenorrhea, functional uterine bleeding, endometriosis, and for contraception.
Definition (CSP) synthetic progestational hormone with actions similar to those of progesterone but functioning as a more potent inhibitor of ovulation; has weak estrogenic and androgenic properties; has been used in treating amenorrhea, functional uterine bleeding, endometriosis, and for contraception.
Concepts Pharmacologic Substance (T121) , Hormone (T125) , Steroid (T110)
MSH D009640
SnomedCT 63758001, 325610003, 326443003, 326332005, 327289001, 326366001, 126102009
LNC LP18482-7, MTHU003100
English Ethinylnortestosterone, Norethisterone, Norpregneninolone, 19-Norpregn-4-en-20-yn-3-one, 17-hydroxy-, (17alpha)-, Norethisterone [combined o/c], Norethisterone [endocrine], Norethisterone [malignancy], Norethisterone [progest o/c], norethindrone, Norethisterone [combined oral contraceptive], Norethisterone [progestogen oral contraceptive], NORETHINDRONE, norethindrone preparations, oral contraceptives norethindrone preparations, norethindrone preparations (medication), Norethindrone [Chemical/Ingredient], norethisterone, Norethisterone [endocrine] (product), Norethisterone [progestogen oral contraceptive] (product), Norethisterone [combined oral contraceptive] (product), Norethisterone [malignancy] (product), Norethindrone preparation, Norethisterone preparation, Norethisterone product, Norethindrone (substance), Norethindrone preparation (product), Norethindrone, Norethindrone preparation (substance), Norethisterone [combined oral contraceptive] (substance), Norethisterone [endocrine] (substance), Norethisterone [malignancy] (substance), Norethisterone [progestogen oral contraceptive] (substance)
Swedish Noretindron
Czech norethindron
Finnish Noretisteroni
Russian NORKOLUT, NORETINDRON, ETINILNORTESTOSTERON, NORPREGNENINOLON, NORETISTERON, НОРКОЛУТ, НОРПРЕГНЕНИНОЛОН, НОРЭТИНДРОН, НОРЭТИСТЕРОН, ЭТИНИЛНОРТЕСТОСТЕРОН
Spanish noretisterona, preparado con noretindrona (producto), noretisterona (producto), preparado con noretisterona, preparado con noretindrona, noretisterona (uso oncológico) (producto), noretisterona [uso endocrino] (producto), noretisterona (anticonceptivo oral combinado), noretisterona (anticonceptivo oral con progestágeno), noretisterona (uso oncológico), noretisterona [uso endocrino], noretisterona (anticonceptivo oral con progestágeno) (producto), noretisterona (anticonceptivo oral combinado) (producto), noretindrona (sustancia), noretindrona, noretisterona (malignidad) (producto), noretisterona (malignidad), preparado de noretindrona (sustancia), Etinilnortestosterona, Noretindrona, Noretisterona, Norpregneninolona
Polish Noretysteron
Japanese プリモルトN, エチニルノルテストステロン, 19-ノルエチステロン, ノルルテン, ミクロノル, ノルエチステロン, ノルルチン, ノアルテン, ノルエチンドロン, ノルプレグネニノロン
French Noréthistérone
German Ethinylnortestosteron, Norethindron, Norethisteron, Norpregneninolon
Italian Noretindrone
Portuguese Etinilnortestosterona, Noretindrona, Noretisterona, Norpregneninolona

Ontology: Norethynodrel (C0028360)

Definition (MSH) A synthetic progestational hormone with actions and uses similar to those of PROGESTERONE. It has been used in the treatment of functional uterine bleeding and endometriosis. As a contraceptive, it has usually been administered in combination with MESTRANOL.
Concepts Pharmacologic Substance (T121) , Hormone (T125) , Steroid (T110)
MSH D009641
SnomedCT 126107003, 82133001
English Norethynodrel, 19-Norpregn-5(10)-en-20-yn-3-one, 17-hydroxy-, (17alpha)-, oral contraceptives norethynodrel, norethynodrel, norethynodrel (medication), Norethynodrel [Chemical/Ingredient], Norethynodrel preparation, Norethynodrel (substance), Norethynodrel preparation (product), Noretynodrel, Norethynodrel preparation (substance), NORETHYNODREL
Swedish Noretynodrel
Czech norethynodrel
Finnish Noretinodreeli
Russian NORETINODREL, НОРЭТИНОДРЕЛ
Japanese ノルエチノドレル, ノルエチノドレール, エニドレル, ノルエチニノドレール
Spanish noretinodrel (producto), preparado con noretinodrel (producto), preparado con noretinodrel, noretinodrel (sustancia), noretinodrel, preparado de noretinodrel (sustancia), Noretinodrel
Polish Noretynodrel
French Norétynodrel
German Norethynodrel
Italian Noretinodrel
Portuguese Noretinodrel