II. Preparations: Norgestimate 250 mcg and Ethinyl Estradiol 35 mcg
- Ortho-Cyclen, MonoNessa or Sprintec
- Cilest (UK)
III. Components
- Norgestimate 25 mcg
- Ethinyl Estradiol 35 mcg
IV. Effect
- Relative Progestational Activity: 0.3 (low)
- Estrogenic Activity: 35 (moderate)
- Androgenic Activity: 0.18 (low)
V. Pill associated problems (Same as Ortho Tri-Cyclen)
- Indications to switch to Modicon
- Acne Vulgaris (lower androgen)
- Increased Appetite (lower Progestin)
- Break-through bleed days 1-9 (more Estrogen)
- Break-through bleed all of month (more Estrogen)
- Major Depression provoked (lower Progestin)
- Menses too light (more Estrogen, less Progestin)
- Indications to switch to Demulen 1/35
- Breast Tenderness or engorgement (lower Estrogen)
- Break-through bleed days 10-21 (more Progestin)
- Headaches (lower Estrogen)
- Heavy Menses (more Progestin or less Estrogen)
- Dysmenorrhea or Menstrual Cramps (more Progestin)
- Moodiness (less Estrogen or more Progestin)
- Weight gain (less Estrogen or more Progestin)
- Indications to switch to Lo/Ovral
- Libido decreased (more androgen)
VI. References
- Cerel-Suhl (1999) Am Fam Physician 60(7):2073 [PubMed]
- Speroff (1993) Obstet Gynecol 81:1034-47 [PubMed]
- Dickey (1998) Managing Contraceptive Pill Patients
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