|
Definition (NCI)
|
A synthetic derivative of progesterone administered as an acetate salt (medroxyprogesterone acetate) with antiestrogenic activity. As a do all progestins, medroxyprogesterone binds to and activates nuclear receptors which subsequently bind to and activate target genes for transcription. As an antiestrogen, this agent may inhibit the growth-stimulating effects of estrogen on estrogen-sensitive tumor cells. (NCI04)
|
|
Definition (NCI_NCI-GLOSS)
|
A hormonal anticancer drug that is also used in cancer prevention. It belongs to the family of drugs called progestins.
|
|
Definition (MSH)
|
(6 alpha)-17-Hydroxy-6-methylpregn-4-ene-3,20-dione. A synthetic progestational hormone used in veterinary practice as an estrus regulator.
|
|
Definition (CSP)
|
synthetic progestin derived from 17-hydroxyprogesterone; a long-acting contraceptive that is effective both orally or by intramuscular injection and has also been used to treat breast and endometrial neoplasms.
|
|
Definition (PDQ)
|
A synthetic derivative of progesterone administered as an acetate salt (medroxyprogesterone acetate) with antiestrogenic activity. As a do all progestins, medroxyprogesterone binds to and activates nuclear receptors which subsequently bind to and activate target genes for transcription. As an antiestrogen, this agent may inhibit the growth-stimulating effects of estrogen on estrogen-sensitive tumor cells. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39813&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=39813&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C629" NCI Thesaurus)
|
| Concepts |
Pharmacologic Substance
(T121)
, Hormone
(T125)
, Steroid
(T110)
|
| MSH |
D008525
|
| SnomedCT |
36621009, 126113007, 27707001 |
| English |
17 alpha-Hydroxy-6 alpha-Methylprogesterone, Methylhydroxyprogesterone, 17 alpha Hydroxy 6 alpha Methylprogesterone, Pregn-4-ene-3,20-dione, 17-hydroxy-6-methyl-, (6alpha)-, 17Alpha-hydroxy-6alpha-methylprogesterone, 6Alpha-methyl-17alpha-hydroxyprogesterone, 6Alpha-methyl-4-pregnen-17alpha-ol-3,20-dione, (6Alpha)-17-hydroxy-6-methylpregn-4-ene-3,20-dione, Medroxyprogesterone [Chemical/Ingredient], medroxyPROGESTERone, MEDROXYPROGESTERONE, medroxyprogesterone, Medroxyprogesterone preparation, Medroxyprogesterone (substance), Medroxyprogesterone preparation (product), MPA, Medroxyprogesterone acetate preparation (substance), Medroxyprogesterone preparation (substance), Medroxyprogesterone |
| Swedish |
Medroxiprogesteron
|
| Czech |
medroxyprogesteron
|
| Finnish |
Medroksiprogesteroni
|
| Russian |
MEDROKSIPROGESTERON, METIPREGNON, METILGIDROKSIPROGESTERON, МЕДРОКСИПРОГЕСТЕРОН, МЕТИЛГИДРОКСИПРОГЕСТЕРОН, МЕТИПРЕГНОН |
| Japanese |
メチルヒドロキシプロゲステロン, メドロキシプロゲステロン |
| Spanish |
preparado con medroxiprogesterona (producto), medroxiprogesterona (producto), preparado con medroxiprogesterona, medroxiprogesterona (sustancia), medroxiprogesterona, preparado de medroxiprogesterona (producto), preparado de medroxiprogesterona (sustancia), preparado de medroxiprogesterona, Medroxiprogesterona, Metilhidroxiprogesterona |
| Croatian |
MEDROKSIPROGESTERON
|
| Polish |
Medroksyprogesteron
|
| French |
Médroxyprogestérone
|
| German |
Medroxyprogesteron, Methylhydroxyprogesteron |
| Italian |
Medrossiprogesterone
|
| Portuguese |
Medroxiprogesterona, Metilidroxiprogesterona |
