II. Dosing
-
Amenorrhea
- Sequential: 5 to 10 mg qd for 5-10 days
- Continuous: 2.5 mg qd
-
Dysfunctional Uterine Bleeding (DUB)
- Sequential: 5-10 mg qd for 5-10 days, start on Day 16
- Postmenopausal Estrogen Replacement (with Premarin)
- Sequential: 2.5 to 5 mg PO qd for last 10 cycle days
- Continuous: 5 to 10 mg qd
III. Adverse effects
- Major Depression
- Breakthrough bleeding
- Increasing dose to 20 to 30 mg daily may reduce bleeding
- However may have increased risk
- Long term lipid and cardiovascular effects?
- Increasing dose to 20 to 30 mg daily may reduce bleeding
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Related Studies
| medroxyprogesterone (on 12/21/2022 at Medicaid.Gov Survey of pharmacy drug pricing) | ||
| MEDROXYPROGESTERONE 10 MG TAB | Generic | $0.14 each |
| MEDROXYPROGESTERONE 150 MG/ML | Generic | $27.39 per ml |
| MEDROXYPROGESTERONE 2.5 MG TAB | Generic | $0.11 each |
| MEDROXYPROGESTERONE 5 MG TAB | Generic | $0.13 each |