Second Generation Progestin

Aka: Second Generation Progestin, Norethindrone Acetate, Ethynodiol Diacetate

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II. Class

  1. 19 Nor-TestosteroneProgestin: Estrane

III. Preparation: Norethindrone Acetate

  1. Relative Progestational Activity: 1.2
    1. Estrogenic Activity: 1.5
    2. Androgenic Activity: 1.6
    3. Endometrial Activity: 0.4
    4. Anti-Estrogen: Active
    5. Anabolic: Active
  2. Preparations: Ethinyl Estradiol
    1. Loestrin 1/20
    2. Loestrin 1.5/30
    3. Norlestrin (1/50, 2.5/50)
    4. Estrostep (1 / 20 - 30 - 35)

IV. Preparation: Ethynodiol Diacetate

  1. Relative Progestational Activity: 1.4
    1. Estrogenic Activity: 3.4
    2. Androgenic Activity: 0.6
    3. Endometrial Activity: 0.4
    4. Anti-Estrogen: Active
    5. Anabolic: Inactive
  2. Preparations
    1. Ethinyl Estradiol
      1. Demulen 1/35
      2. Demulen 1/50
    2. Mestranol
      1. Ovulen (1/100)

V. References

  1. Cerel-Suhl (1999) Am Fam Physician 60(7):2073 [PubMed]
  2. Speroff (1993) Obstet Gynecol 81:1034-47 [PubMed]
  3. Dickey (1998) Managing Contraceptive Pill Patients

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