Fourth Generation Progestin

Aka: Fourth Generation Progestin, Desogestrel, Gestodene, Norgestimate

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II. Class

  1. 19 Nor-TestosteroneProgestin: Gonane

III. Preparations: Desogestrel

  1. Relative Progestational Activity: 9.0
    1. Estrogenic Activity: 0
    2. Androgenic Activity: 3.4
    3. Endometrial Activity: 8.7
  2. Preparations
    1. Desogen (0.15/30)
    2. Ortho-Cept (0.15/30)
    3. Mircette (0.15/20)
    4. Cyclessa (triphasic: 0.100 - 0.125 - 0.150 / 25)

IV. Preparations: Gestodene

  1. Relative Progestational Activity: 12.6
    1. Estrogenic Activity: 0
    2. Androgenic Activity: 8.6
    3. Endometrial Activity: 12.6
  2. Preparations
    1. Melodene (Spain) or Minesse (Israel) (0.060/15)
    2. Femodette (UK, 0.075/20)
    3. Femodene or Minulet (UK, 0.075/30)
    4. Triadene or Tri-Minulet (UK, 0.050/30 - 0.070/40 - 0.1/30)

V. Preparations: Norgestimate

  1. Relative Progestational Activity: 1.3
    1. Estrogenic Activity: 0
    2. Androgenic Activity: 1.9
    3. Endometrial Activity: 1.2
  2. Preparations
    1. Ortho-Cyclen (0.15/30)
    2. Ortho Tri-Cyclen (0.18/35 - 0.25/35)

VI. References

  1. Cerel-Suhl (1999) Am Fam Physician 60(7):2073 [PubMed]
  2. Speroff (1993) Obstet Gynecol 81:1034-47 [PubMed]
  3. Dickey (1998) Managing Contraceptive Pill Patients

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Related Studies

Cost: Medications

desogestrel (on 12/21/2022 at Medicaid.Gov Survey of pharmacy drug pricing)
DESOGESTREL-EE 0.15-0.03 MG TB Generic $0.15 each
FPNotebook does not benefit financially from showing this medication data or their pharmacy links. This information is provided only to help medical providers and their patients see relative costs. Insurance plans negotiate lower medication prices with suppliers. Prices shown here are out of pocket, non-negotiated rates. See Needy Meds for financial assistance information. GoodRx is another tool for finding lower drug prices.

Related Topics in Pharmacology

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