II. Indication
- First line agent for Open Angle Glaucoma
III. Contraindications
- Active Uveitis
IV. Mechanism
- Prostaglandin analogs that increase uveoscleral aqueous outflow (lowers IOP 25 to 35%)
V. Medications (Teal Caps)
- Latanoprost (Xalatan) 0.005% one drop daily
- Bimatoprost (Lumigan) 0.03% one drop daily
- Travoprost (Travatan) 0.004% one drop daily
- Unoprostone (Rescula) 0.15% one drop daily
- Tafluprost (Zioptan) 0.0015% one drop daily
- Latanoprostene bunod (Vyzulta)
- Breaks down to Latanoprost and nitric oxide, but with no significant benefit over Latanoprost alone
- Released in 2018, costing 10x the cost of Latanoprost alone (which is $12 per bottle)
- (2018) Presc Lett 25(5): 28
VI. Efficacy: Latanoprost
- Highly effective, low side effect agent
- Currently most prescribed Glaucoma agent worldwide
- References
VII. Adverse Effects
VIII. References
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Related Studies
| latanoprost (on 12/21/2022 at Medicaid.Gov Survey of pharmacy drug pricing) | ||
| LATANOPROST 0.005% EYE DROPS | Generic | $1.75 per ml |
| xalatan (on 8/17/2022 at Medicaid.Gov Survey of pharmacy drug pricing) | ||
| XALATAN 0.005% EYE DROPS | Generic | $1.75 per ml |
| bimatoprost (on 12/21/2022 at Medicaid.Gov Survey of pharmacy drug pricing) | ||
| BIMATOPROST 0.03% EYE DROPS | Generic | $31.11 per ml |
| BIMATOPROST 0.03% EYELASH SOLN | Generic | $26.03 per ml |
| lumigan (on 1/14/2022 at Medicaid.Gov Survey of pharmacy drug pricing) | ||
| LUMIGAN 0.01% EYE DROPS | $87.53 per ml | |
| travoprost (on 12/21/2022 at Medicaid.Gov Survey of pharmacy drug pricing) | ||
| TRAVOPROST 0.004% EYE DROP | Generic | $26.10 per ml |
| travatan (on 7/27/2022 at Medicaid.Gov Survey of pharmacy drug pricing) | ||
| TRAVATAN Z 0.004% EYE DROP | Generic | $22.25 per ml |
| tafluprost (on 2/22/2023 at Medicaid.Gov Survey of pharmacy drug pricing) | ||
| TAFLUPROST 0.0015% EYE DROP | Generic | $4.29 each |
| zioptan (on 10/19/2022 at Medicaid.Gov Survey of pharmacy drug pricing) | ||
| ZIOPTAN 0.0015% EYE DROP | Generic | $4.78 each |
| ZIOPTAN 0.0015% EYE DROPS | $7.39 each | |
| vyzulta (on 1/1/2022 at Medicaid.Gov Survey of pharmacy drug pricing) | ||
| VYZULTA 0.024% OPHTH SOLUTION | $87.46 per ml | |