Definition (NCI)
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A pure, stabilized form of podophyllin, in which only the biologically active portion of the compound is present. Podophyllotoxin is a toxic, polycyclic antimitotic agent isolated primarily from the rhizome of the plant Podophyllum peltatum. This agent is formulated for topical applications. (NCI04)
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Definition (MSH)
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A lignan (LIGNANS) found in PODOPHYLLIN resin from the roots of PODOPHYLLUM plants. It is a potent spindle poison, toxic if taken internally, and has been used as a cathartic. It is very irritating to skin and mucous membranes, has keratolytic actions, has been used to treat warts and keratoses, and may have antineoplastic properties, as do some of its congeners and derivatives.
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Concepts |
Organic Chemical
(T109)
, Pharmacologic Substance
(T121)
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MSH |
D011034
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SnomedCT |
76575003, 415128000, 108931008, 415127005, 7959004 |
English |
Podofilox, Podophyllotoxin, Furo(3',4':6,7)naphtho(2,3-d)-1,3-dioxol-6(5aH)-one, 5,8,8a,9-tetrahydro-9-hydroxy-5-(3,4,5-trimethoxyphenyl)-, (5R-(5alpha,5abeta,8aalpha,9alpha))-, PODOFILOX, podofilox (medication), podofilox, Podophyllotoxin [Chemical/Ingredient], podophyllotoxin, Podofilox (substance), Podofilox preparation (product), Podofilox preparation, Podophyllotoxin (substance), Podophyllotoxin product, Podophyllotoxin product (product) |
Swedish |
Podofyllotoxin
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Czech |
podofylotoxin
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Finnish |
Podofyllotoksiini
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Russian |
PODOFILLOTOKSIN, EPIPODOFILLOTOKSIN, ПОДОФИЛЛОТОКСИН, ЭПИПОДОФИЛЛОТОКСИН |
Japanese |
ポドフィロックス, ポドフィロトキシン, エピポドフィロトキシン |
Spanish |
producto con podofilotoxina (producto), podofilotoxina (producto), producto con podofilotoxina, preparación con podofilox (producto), preparación con podofilox, podofilox, preparación con podofilotoxina, podofilox (sustancia), podofilotoxina (sustancia), podofilotoxina, Podofilotoxina |
Italian |
Podofilox, Podofillotossina |
Polish |
Podofilotoksyna
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French |
Podophyllotoxine
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German |
Podophyllotoxin
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Portuguese |
Podofilotoxina
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