II. Indication
- Genital Warts (home application)
III. Contraindications
- Not recommended for mucosal lesions
- Avoid on perianal, rectal, Urethral, vaginal warts
IV. Background
- Purified form of Podophyllotoxin extract
V. Mechanism
- Stops division of infected cells
VI. Preparation
- Podofilox (Condylox) 0.5% solution or gel
- Apply solution with cotton swab
- Apply Gel with finger (easier to apply)
VII. Technique
- Cycle application
- Apply twice daily for 3 days
- Wait 4 days, then restart application cycle
- Repeat cycle for up to 4 weekly cycles (maximum 10 cm^2)
VIII. Advantages
- Less irritating and as effective than Podophyllin
- Can use in conjunction with other methods
IX. Precautions
- Allow to dry before moving around
- Do not wash off
- Do not exceed 0.5 ml per day
X. Efficacy
- Works best on moist mucosal skin sites
- Does not work on keratinized Epidermis
- Similar efficacy to Imiquimod
- Complete clearance of Genital Warts in 45-77% with a 4-33% recurrence rate
- Buck (2006) Clin Evid (15): 2149-61 [PubMed]
XI. Safety
- Pregnancy Category C
Images: Related links to external sites (from Bing)
Related Studies
| condylox (on 1/19/2022 at Medicaid.Gov Survey of pharmacy drug pricing) | ||
| CONDYLOX 0.5% GEL | $173.30 per gram | |
| podofilox (on 12/21/2022 at Medicaid.Gov Survey of pharmacy drug pricing) | ||
| PODOFILOX 0.5% TOPICAL SOLN | Generic | $12.95 per ml |