II. Indications
-
Psoriasis
- Primary use
-
Acne Vulgaris
- Other Comedolytics are better tolerated (Retin A, Adapalene)
IV. Preparations
- Cream 0.05%, 0.1%
- Gel 0.05%, 0.1%
V. Dosing
- Applied each day
- Quick onset of benefit
- Start at 0.05% gel, may advance to 0.1% gel
VI. Efficacy
- Under 50% have moderate to marked benefit
- Best used in combination with topicals
- Benefit may last for several weeks after stopping
VII. Adverse Effects
- Local irritation is common
- Erythema in almost everyone
- Peeling and dryness
- Pruritus, stinging and burning
- Not tolerated by 10% of patients
- Risk of Koebner Reaction
- Results in larger area Psoriasis
- Apply strictly to lesion
VIII. Safety
- Pregnancy Category X
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Related Studies
tazarotene (on 12/21/2022 at Medicaid.Gov Survey of pharmacy drug pricing) | ||
TAZAROTENE 0.05% GEL | Generic | $8.14 per gram |
TAZAROTENE 0.1% CREAM | Generic | $2.86 per gram |