II. Pathophysiology: Arthropod types
- Arachnids (8 legs)- Spiders- See Spider Bite
- Black Widow Spider (Lactodectus mactans)
- Brown Recluse Spider (Loxosceles reclusa)
- Precautions- "Spider Bites" are typically not due to Spiders, but rather other causes (e.g. MRSA Cellulitis)
- Most Spider Bites are benign (not black widow or brown recluse)- Need only minimal local therapy (Wound Cleansing, cold therapy)
 
 
 
- Mites
- Scorpions
- Ticks- See Tick Bite
- See Vector Borne Disease
 
 
- Spiders
- Insects (6 legs)- Diptera (2-winged Insects)
- Siphonaptera- Fleas
 
- Hemiptera ("true bugs")
- Psocodea
- Hymenoptera (includes Stinging Insects)- See Stinging Insect Bite
- Apidae (Bees)- Honey bees
- Bumble bees
 
- Vespidae- Wasps
- Yellow Jackets
- Hornets
 
- Formicidae (Stinging Ants)
 
 
III. Signs
- Most "Spider Bites" are due to some other cause
- Pruritic, Red Papules- Typical Insect Bite (e.g. Mosquito Bite or biting midge such as no-see-ums, Sand Fly)
 
- Pruritic welts along constrictive clothing lines (waist band or sock line)
- Clustered or linear Papules at the ankles
IV. Differential Diagnosis: Insect Bite Reaction
- See Annular Lesion
- See Stinging Insect Reaction
- Folliculitis
- Impetigo
- Cellulitis
- Shingles
- Contact Dermatitis
- 
                          Erythema Migrans
                          - Most Insect Bite reactions are localized (typically <2.5 to 5 cm in size) and resolves in first 48 hours
- Erythema Migrans insyead, continues to expand at >48 hours to diameters often >10 cm
 
- 
                          Erythema Multiforme
                          - Multiple target lesions each typically <2 cm diameter
 
- 
                          Granuloma Annulare
                          - Scaling erythematous lesions with central clearing (esp. hands and feet)
 
- 
                          Methicillin Resistant Staphylococcus Aureus (MRSA)- Lesions with necrotic central eschar
 
- Tinea Corporis
- Urticaria
V. Complications
- Anaphylaxis or other serious Allergic Reaction
- Papular Urticaria
- Vector Borne Disease (e.g. Lyme Disease with Erythema Migrans)
- 
                          Cellulitis
                          - Inflammation out of proportion to Insect Bite
- Regional Lymphadenopathy
- Ascending lymphangitis
 
VI. Management: General
- Remove Stinger with forceps (avoid pinching the Stinger gland)
- Apply ice pack for 10-20 minutes per hour for 3 hours- Contraindicated in Tarantula Bite
 
- Treat itch symptomatically- Oral Benadryl for nighttime itch, Zyrtec for daytime itch
- Cool compresses
- Oral Analgesics (e.g. Acetaminophen or NSAIDs)
- Anti-irritant agents (e.g. sarna)
- Protective agents (e.g. calamine)
- Topical Corticosteroids (low potency such as 1% Hydrocortisone, brief use) may be considered
- Avoid topical Antihistamines (e.g. topical Benadryl) due to Contact Dermatitis risk
 
VII. Management: Acute Allergic Reaction
- See Anaphylaxis
- See Stinging Insect Allergy
- Prescribe Epi-Pen for emergency use for those with Anaphylaxis history
VIII. Management: Suspected Cellulitis
- See Cellulitis for Antibiotic selection
- Tetanus Prophylaxis
IX. Prevention
- See Prevention of Vector-borne Infection
- Check clothes for Insects before donning
- Avoid times of peak Insect activity (dawn and dusk)
- Avoid habitats- Woodpiles
- Crawl spaces
- Corners of buildings
- Standing water
- Dense vegetation
 
- Dress for working outdoors- Keep skin covered by clothing- Wear gloves
- Shirt tucked into pants
- Pants tucked into socks
- Wear a hat and high collar
- Avoid loose clothing
 
- Avoid Insect attractants- Avoid bright colors (wear light colored clothing)
- Avoid perfumes
 
 
- Keep skin covered by clothing
- 
                          Insect Repellents- See Insect Repellent
- DEET (<30% is safe in young children)
- Permethrin (Elimite, Nix) on clothes- Ticks
 
 
X. References
- Norris (1998) Physician and Sports Med 26(7):47-58
- Herness (2022) Am Fam Physician 106(2): 137-47 [PubMed]
- Juckett (2013) Am Fam Physician 88(12): 841-7 [PubMed]
- Kemp (1998) Postgrad Med 103(6):88-106 [PubMed]
