II. Indications
- See Sedating Antihistamine
- Local Anesthesia for Lidocaine Allergy
III. Dosing: Standard
- Adult: 25-50 mg PO/IV/IM q6h
- Child: 5 mg/kg/day divided qid (12.5 mg/5 ml)
IV. Preparation: Diphenhydramine 1% (for Local Anesthesia)
- Dilute Diphenhydramine 5% in Normal Saline (1:4)
- Longer delay to onset of action than Lidocaine
- Shorter duration of action than Lidocaine
V. Adverse Effects
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Related Studies
| diphenhydramine (on 12/21/2022 at Medicaid.Gov Survey of pharmacy drug pricing) | ||
| DIPHENHYDRAMINE 12.5 MG/5 ML | Generic OTC | $0.01 per ml |
| DIPHENHYDRAMINE 25 MG CAPSULE | Generic OTC | $0.03 each |
| DIPHENHYDRAMINE 25 MG TABLET | Generic OTC | $0.04 each |
| DIPHENHYDRAMINE 50 MG CAPSULE | Generic OTC | $0.02 each |
| DIPHENHYDRAMINE 50 MG/ML VIAL | Generic | $0.85 per ml |