II. Definitions
- Agitation
- Behavior that is loud, hyperactive, disruptive, threatening or disruptive
-
Agitated Delirium (Excited Delirium)
- Psychomotor Agitation, Delirium and sweating often with Violent Behavior, increased strength, hyperthermia
III. Precautions
- See Agitated Delirium
- Patient Agitation is highly dangerous for both patients and staff
- Assaults by patients against nurses and physicians in the Emergency Department is common
- Follow established protocols for deescalation, Physical Restraint and Sedation of the Violent Patient
- Employ acute intensive management to prevent injury to patients and staff
- Agitation is frequently associated with secondary causes (see below) as well as injuries (e.g. Closed Head Injury)
- Ensure patient and staff safety, and then evaluate red flags (see below)
- Psychiatric causes of acute Agitation are a diagnosis of exclusion
- Red Flags for Underlying Medical Causes
- See Delirium
- Extremes of age (young children, elderly)
- Abnormal Vital Signs (e.g. fever, significant Tachycardia, Hypoxia)
- Trauma
- Delirium
- Visual Hallucinations
- Neurologic Abnormalities
- Acute Intoxication
- Unknown Ingestion
- Signs of Substance Withdrawal
- Serious comorbidities (e.g. Immunosuppression)
- Lack of prior mental illness
IV. Causes
- See Agitated Delirium
- See Altered Mental Status Differential Diagnosis
- See Psychosis
- See Delirium
- Neurologic
- Cerebrovascular Accident
- Intracranial Hemorrhage (Acute Subdural Hematoma, Subarachnoid Hemorrhage)
- Agitation is a key presentating finding in 10% of severe Traumatic brain injuries
- Brooke (1992) Arch Phys Med Rehabil 73(4): 320-23 [PubMed]
- Toxicology
- Metabolic
- Thermoregulation
- Infection
- Respiratory
- Hypoxia
- Hypercarbia
- Psychiatric Disorder with Psychosis
-
Dementia
- See Agitation in Dementia
- Often related to physical discomfort or illness
V. History
- Review medical record including recent emergency visits and hospitalizations
- Obtain history from EMS staff on arrival
- Obtain history from family
VI. Exam
- See Emergency Psychiatric Evaluation
- Agitation rating scales
- Evaluate for secondary causes
- Evaluate for Decision Making Capacity
VII. Evaluation
- See Agitated Delirium
- See Altered Mental Status
- See Unknown Ingestion
- See Psychosis
- See Delirium
- Evaluate for easily reversible causes
- Bedside Glucose (Hypoglycemia)
- Hypoxia (Oxygen Saturation)
- Diagnostics to consider
- Electrocardiogram
- Comprehensive Metabolic Panel
- Complete Blood Count
- Urinalysis
- Thyroid Stimulating Hormone
- Toxicology Screening
- Neurologic Testing
VIII. Management
- See Agitation Management
- See Agitated Delirium
- See Agitation in Dementia
- See Physical Restraint
- See Chemical Restraint
IX. References
- Roppolo, Klinger, Leaf (2019) Crit Dec Emerg Med 33(2): 3-10
- Shanks, Ginsburg and Leaf (2023) Crit Dec Emerg Med 37(9): 4-10