II. Indications
- Anxiety Disorder
- Preanesthetic medication
- Status Epilepticus
III. See Also
IV. Class
- Medium Acting Benzodiazepine
V. Pharmacokinetics
- Half Life: 10-20 hours
- Onset: 2-3 minutes with IV dosing
- Duration: 12-24 hours
VI. Dosing: General
-
Anxiety Disorder
- Dose: 0.5 to 2 mg IV, IM or orally every 6 to 8 hours as needed
- Maximum Daily Dose: 4 mg
-
Status Epilepticus
- IV: 0.1 mg/kg IV (<2 mg/minute) up to 4 mg
- Rectal: 0.1 mg/kg up to 4 mg
- Avoid IM Lorazepam (unreliable in Status Epilepticus)
- May repeat once in 5-10 minutes
- Avoid more than 2 doses in children due to risk of respiratory depression
VII. Dosing: Equivalent (for Benzodiazepine Withdrawal)
- Valium = Dose x5.0
- Phenobarbital = Dose x15.0
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Related Studies
| lorazepam (on 12/21/2022 at Medicaid.Gov Survey of pharmacy drug pricing) | ||
| LORAZEPAM 0.5 MG TABLET | Generic | $0.04 each |
| LORAZEPAM 1 MG TABLET | Generic | $0.04 each |
| LORAZEPAM 2 MG TABLET | Generic | $0.07 each |
| LORAZEPAM 2 MG/ML ORAL CONCENT | Generic | $0.53 per ml |
| LORAZEPAM INTENSOL 2 MG/ML | Generic | $0.53 per ml |
| ativan (on 1/1/2022 at Medicaid.Gov Survey of pharmacy drug pricing) | ||
| ATIVAN 0.5 MG TABLET | Generic | $0.04 each |
| ATIVAN 1 MG TABLET | Generic | $0.04 each |