Zaleplon

Aka: Zaleplon, Sonata

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II. Mechanism

  1. Nonbenzodiazepine Hypnotic Agent (Benzodiazepine Receptor Agonist)

III. Indication

  1. Insomnia
  2. Consider for early awakening in middle of night

IV. Pharmacokinetics

  1. Half-Life: 1 hour
  2. Peak Onset: 30 minutes
  3. Duration
    1. Typically 4 hours, but may be as long as 6-8 hour
  4. Metabolized by CYP450 3A4

V. Dosing

  1. Start: 5-10 mg orally at bedtime
  2. Elderly: 5 mg orally at bedtime
  3. Maximum: 20 mg orally at bedtime

VI. Adverse Effects

  1. See Nonbenzodiazepine Hypnotic Agent for common effects
  2. Altered color Perception

VII. Advantages

  1. See Nonbenzodiazepine Hypnotic Agent
  2. Effective in middle of night awakening
    1. Can take mid-way through sleep period

VIII. Resources

  1. Zaleplon (DailyMed)
    1. https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=57a1a11d-7767-4caf-b98a-75d7561d9165

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Related Studies

Cost: Medications

zaleplon (on 12/21/2022 at Medicaid.Gov Survey of pharmacy drug pricing)
ZALEPLON 10 MG CAPSULE Generic $0.16 each
ZALEPLON 5 MG CAPSULE Generic $0.18 each
FPNotebook does not benefit financially from showing this medication data or their pharmacy links. This information is provided only to help medical providers and their patients see relative costs. Insurance plans negotiate lower medication prices with suppliers. Prices shown here are out of pocket, non-negotiated rates. See Needy Meds for financial assistance information. GoodRx is another tool for finding lower drug prices.

Related Topics in Pharmacology

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