II. Mechanism
- Phenothiazine
- Potent Dopamine D2 Receptor Antagonist
III. Dosing: Schizophrenia
- Adult IM or Oral Immediate Formulation
- Start 2.5 mg IM or orally twice daily
- Titrate to 10 mg/day IM or 20 mg/day orally divided every 6 to 8 hours
- Maximum Dose: 40 mg
- Depot IM/SC Long Acting Formulation (Fluphenazine enanthate, Fluphenazine decanoate)
- Stabilize on oral dose before initiating depot dose
- Start 12.5 to 25 mg IM or SQ every 4 to 6 weeks (equivalent to 10 to 20 mg/day of oral dose)
IV. Adverse Effects
V. Safety
- Unknown safety in pregnancy
- Unknown safety in Lactation
VI. Resources
VII. References
- (2016) Med Lett Drugs Ther 58(1510): 160-5
- Olson (2020) Clinical Pharmacology, Medmaster Miami, p. 42-3
- Hamilton (2020) Tarascon Pocket Pharmacopoeia
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Related Studies
| fluphenazine (on 12/21/2022 at Medicaid.Gov Survey of pharmacy drug pricing) | ||
| FLUPHENAZINE 1 MG TABLET | Generic | $0.85 each |
| FLUPHENAZINE 10 MG TABLET | Generic | $2.05 each |
| FLUPHENAZINE 2.5 MG TABLET | Generic | $1.27 each |
| FLUPHENAZINE 5 MG TABLET | Generic | $1.86 each |
| FLUPHENAZINE DEC 125 MG/5 ML | Generic | $13.70 per ml |