II. Class
- Long acting Benzodiazepine
III. Indications
-
Insomnia
- Short-term use only
IV. Dose
-
Insomnia
- Start 7.5 orally at bedtime
- Maximum: 15 mg orally at bedtime (7.5 mg in the elderly)
V. Safety
- Pregnancy Category X (esp. first trimester)
- Avoid in Lactation
- Schedule IV Controlled Substance
VI. Pharmacokinetics
- Half-Life: 39 hours
VII. Metabolism
VIII. Resources
IX. References
- (2019) Med Lett Drugs Ther 61(1578): 121-6
- (2020) Presc Lett, Resource #361206, Appropriate Use of Benzodiazepines
- Olson (2020) Clinical Pharmacology, Medmaster Miami, p. 55
- Hamilton (2020) Tarascon Pocket Pharmacopoeia