II. Indications

  1. Narcolepsy
  2. Non-FDA approved use
    1. Attention Deficit Hyperactivity Disorder
    2. Fatigue in Multiple Sclerosis
    3. Excessive Sleepiness in myotonic dystrophy

III. Contraindications (relative)

  1. Coronary Artery Disease
  2. Hypertension
  3. Other cardiovascular disease

IV. Mechanism

  1. Stimulant

V. Dosing: Adults

  1. ADHD: 100-300 mg PO qd (Not FDA approved)
  2. Narcolepsy: 200 mg qAM

VI. Dosing: Children Age >5 years

  1. ADHD: 50-100 mg PO qd (Not FDA approved)

VII. Efficacy: Narcolepsy

  1. May be slightly less effective then agents above
  2. Less addictive potential then agents above
  3. (1999) Med Lett Drugs Ther 41(1049):30-2 [PubMed]

VIII. Efficacy: ADHD

IX. Adverse Effects

X. References

  1. (2003) Lexi-Comp Drug Database for Pocket PC (7/9/03)

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