II. Indications
III. Efficacy
- One year quit rate 23% (13% for Placebo)
IV. Preparations
V. Technique
- Stop smoking first before starting gum
- Avoid food or drink 15 minutes before gum
- Avoid acidic foods and beverages 30 minutes prior to use
- Chew one piece of gum
- Urge to smoke
- Withdrawal symptoms
- Chew slowly 30 minutes/piece
- Keep gum in buccal area
- Chew 1-2 times every few minutes
- Excessive chewing results in adverse effects
- Park piece between gum and cheek between chewing
VI. Dosing
- Timing
- Chew one piece slowly every 1-2 hours
- Prescribing
- Write for 2 boxes of gum initially
- Taper dose after 3 months, off gum by 6 months
- Taper schedule for those on 4 mg chew
- Initial: 10-15 pieces per day (4 mg dose) for 2 weeks
- Maximum dose: 20 pieces per day (4 mg dose)
- After 2 weeks: 10-15 pieces per day (2 mg dose)
- Initial: 10-15 pieces per day (4 mg dose) for 2 weeks
VII. Adverse Effects: Gastrointestinal affects
- Prevented by chewing gum slowly (see protocol above)
- Nausea
- Dyspepsia
- Pharyngitis
VIII. Precautions
- Pregnancy Category C
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Related Studies
Concepts | Pharmacologic Substance (T121) , Organic Chemical (T109) |
MSH | D061485 |
SnomedCT | 77544001 |
English | nicotine polacrilex (medication), nicotine polacrilex [Chemical/Ingredient], Nicotine Polacrilices, Nicotine Polacrilex, Polacrilex, Nicotine, Polacrilices, Nicotine, nicotine polacrilex, Nicotine polacrilex, Nicotine polacrilex (substance), NICOTINE POLACRILEX |
French | Polacrilex de nicotine, Nicotine Polacrilex |
German | Nikotin Polacrilex |
Spanish | nicotina polacrilex (sustancia), nicotina polacrilex |
Ontology: Nicotine Chewing Gum (C0599654)
Definition (NCI_NCI-GLOSS) | A chewing gum that contains a small dose of nicotine, which enters the blood by being absorbed through the lining of the mouth. This helps stop nicotine cravings and relieves symptoms that occur when a person is trying to quit smoking. A prescription is not needed for nicotine gum. |
Definition (NCI) | A chewing gum containing nicotine used as a substitute for the active ingredient in tobacco. Nicotine chewing gum reduces the withdrawal symptoms associated with smoking cessation. |
Concepts | Clinical Drug (T200) |
MSH | D061485 |
SnomedCT | 346593007 |
LNC | LA14322-4 |
English | nicotine gum, gum nicotine, Nicotine Chewing Gum, Nicotine Chewing Gums, Chewing Gum, Nicotine, Chewing Gums, Nicotine, Gum, Nicotine Chewing, Gums, Nicotine Chewing, Nicotine gum, Nicotine chewing gum, Nicotine chewing gum (product), Nicotine chewing gum (substance), Nicotine Gum |
French | Chewing-gum à la nicotine, Gomme à la nicotine, Gomme à mâcher à la nicotine |
Czech | žvýkačka nikotinová |
German | Nikotinkaugummi, Nikotin-Kaugummi |
Norwegian | Nikotintyggegummi |
Spanish | nicotina, chicle (producto), nicotina, chicle, nicotina, goma de mascar |
Ontology: Nicorette (C0701400)
Concepts | Pharmacologic Substance (T121) , Organic Chemical (T109) |
MSH | D061485 |
English | nicorette, Nicorette |
French | Nicorette |
Czech | Nicorette |
German | Nicorette |
Norwegian | Nicorette |