II. Indications
-
Insomnia
- Short-term use only
III. Dosing: Adults
- Dose: 15-30 mg at bedtime as needed for Insomnia
- Max Daily Dose: 30 mg (15 mg in elderly or debilitated)
IV. Dosing: Equivalents with other Benzodiazepines
- Valium = Flurazepam Dose x 0.6
- Phenobarbital = Flurazepam Dose x2.0
V. Precautions
- Drug accumulation in elderly
VI. Pharmacokinetics
VII. Adverse Effects
VIII. Advantages
- Long half life prevents rebound Insomnia
- Rebound is often seen in other Benzodiazepines used >30 days
IX. Safety
- Pregnancy Category X (all trimesters)
- Avoid in Lactation
- Schedule IV Controlled Substance
X. Resources
XI. References
- (2019) Med Lett Drugs Ther 61(1578): 121-6
- (2020) Presc Lett, Resource #361206, Appropriate Use of Benzodiazepines
- Olson (2020) Clinical Pharmacology, Medmaster Miami, p. 55
- Hamilton (2020) Tarascon Pocket Pharmacopoeia