II. Indications
- Schizophrenia
- Bipolar Disorder (Type 1)
- Acute Mania or mixed disorder
III. Mechanism
- Atypical Antipsychotic
- Dopamine Partial Agonist at D2 and D3 receptors
IV. Dosing: Schizophrenia, Bipolar 1 Disorder, Mania
- Start 1.5 mg orally daily
- May increase to 3 mg orally daily after the first day (after 2 weeks in Bipolar Depression)
- Maximum: 6 mg/day
V. Drug Interactions
VI. Safety
- Unknown safety in pregnancy and Lactation
VII. Adverse Effects
- See Atypical Antipsychotic
- Hyperprolactinemia
- Weight gain (low risk)
- Somnolence
- Extrapyramidal Side Effects (high risk)
- Akathisia
- Tremor
VIII. Resources
IX. References
- (2016) Med Lett Drugs Ther 58(1510): 160-5
- Olson (2020) Clinical Pharmacology, Medmaster Miami, p. 42-3
- Hamilton (2020) Tarascon Pocket Pharmacopoeia
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Related Studies
| vraylar (on 1/14/2022 at Medicaid.Gov Survey of pharmacy drug pricing) | ||
| VRAYLAR 1.5 MG CAPSULE | $41.98 each | |
| VRAYLAR 3 MG CAPSULE | $41.94 each | |
| VRAYLAR 4.5 MG CAPSULE | $41.93 each | |
| VRAYLAR 6 MG CAPSULE | $41.87 each | |