II. Indications
- Anxiety Disorder
- Anxiety with comorbid Major Depression
- Alcohol Withdrawal
III. Class
- Short acting Benzodiazepine
IV. Pharmacokinetics
- Half Life: 8 to 15 hours
- Metabolism via Glucuronidation to inactive metabolites
V. Dosing: General
-
Anxiety Disorder
- Elderly: 10 mg orally 3 times daily (and may advance to 15 mg orally 3 to 4 times daily)
- Moderate: 10 to 15 mg orally 3 to 4 times daily
- Severe: 15 to 30 mg orally 3 to 4 times daily
- Maximum Daily Dose: 120 mg/day
- Acute Alcohol Withdrawal
- Give 15 to 30 mg orally three to four times daily
VI. Dosing: Equivalent dosing (for Benzodiazepine Withdrawal)
- Valium = Dose x1.0
- Phenobarbital = Dose x3.0
VII. Safety
- Pregnancy Category D
- Avoid in Lactation
- Schedule IV Controlled Substance
VIII. Resources
IX. References
- (2019) Med Lett Drugs Ther 61(1578): 121-6
- (2020) Presc Lett, Resource #361206, Appropriate Use of Benzodiazepines
- Olson (2020) Clinical Pharmacology, Medmaster Miami, p. 55
- Hamilton (2020) Tarascon Pocket Pharmacopoeia
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Related Studies
| oxazepam (on 12/21/2022 at Medicaid.Gov Survey of pharmacy drug pricing) | ||
| OXAZEPAM 10 MG CAPSULE | Generic | $0.83 each |
| OXAZEPAM 15 MG CAPSULE | Generic | $1.07 each |
| OXAZEPAM 30 MG CAPSULE | Generic | $1.24 each |