II. Indications

  1. Cerebrovascular Accident
    1. Differentiate Hemorrhagic CVA from Ischemic CVA
    2. More sensitive than LP for Intracranial Hemorrhage
    3. Test Sensitivity diminishes from time of Hemorrhagic CVA
      1. Test Sensitivity 95-100% at 12 hours from onset
      2. Test Sensitivity 50% at 7 days from onset
      3. Hemorrhagic CVA is not detectable on CT Head at 2-3 weeks from onset
      4. Suarez (2006) N Engl J Med 354(4): 387-96 [PubMed]
  2. Brain Tumors (larger than 2-4 mm)
    1. Enhanced with iodinated Contrast Material
  3. Hydrocephalus
    1. Temporal horn of the Lateral Ventricle dilates (axial width >=5 mm) early in Hydrocephalus
      1. Appear rounded as Hydrocephalus develops (contrast with their normal curved-slit appearance)
    2. Third Ventricle appears O-Shaped when dilated from downstream CSF obstruction
      1. Third Ventricle is normally has a more slit-like appearance
  4. Intracranial Bleeding
    1. Epidural Hematoma
    2. Subdural Hematoma
    3. Intraparenchymal Hemorrhage
    4. Subarachnoid Hemorrhage (Thunderclap Headache)
  5. Evaluation of Traumatic Head Injury
    1. CT Head in every Severe Head Injury
    2. CT Head in every Moderate Head Injury
    3. See Head Injury CT Indications
    4. See Head Injury CT Indications in Children

III. Interpretation: General

  1. See CT Scan Window Width
    1. Describes CT Windows for Brain Window or Subdural Window
  2. Systematic Head CT Approach Mnemonic: "Blood Can Be Very Bad"
    1. B: Blood
    2. C: Cisterns
    3. B: Brain
    4. V: Ventricles
    5. B: Bone

IV. Interpretation: Hemorrhage

  1. Hemorrhage appearance on CT changes with time
    1. Acute Hemorrhage: Hyperdense (light, white)
      1. Whiter than brain matter
    2. Subacute Hemorrhage: Isodense
      1. Similar density to brain matter and may be missed
    3. Chronic Hemorrhage: Hypodense (dark)
      1. Darker than brain matter
      2. Old Subdural Hematoma may appear as a hygroma
  2. Hemorrhage mimics: Contrast Staining
    1. Contrast staining refers to contrast deposition in extravascular brain parenchyma after IV contrast
      1. Non-contrast CT Head demonstrates a bright appearance similar to CNS Hemorrhage appearance
    2. Contrast staining occurs with transient increased blood brain permeability
      1. Intracranial neoplasm
      2. Ischemic CVA
      3. Intra-arterial clot extraction
    3. Contrast staining differs from CNS Hemorrhage in several ways
      1. Contrast staining typically resolves more quickly than Hemorrhage (24-48 hours)
      2. Contrast staining remains confined to the original lesion (while Hemorrhage extends)
      3. Contrast staining typically has attenuation <50 HU following endovascular thrombectomy
    4. Additional Imaging can also help distinguish between contrast staining and Hemorrhage
      1. Serial CT Head (repeated in 6 hours, traditional method)
      2. Dual energy CT
      3. MRI with susceptibility weighted imaging
    5. References
      1. Broder (2025) Crit Dec Emerg Med 39(10): 26-8

V. References

  1. Broder (2024) Crit Dec Emerg Med 38(7): 22-3
  2. Broder (2021) Crit Dec Emerg Med 35(5): 10-1
  3. Haydel (2000) N Engl J Med 343:100-5 [PubMed]

Images: Related links to external sites (from Bing)