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Definition (NCI)
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Delayed-type hypersensitivity reaction to foreign proteins derived from an animal serum. It occurs approximately six to twenty one days following the administration of the foreign antigen. Symptoms include fever, arthralgias, myalgias, skin eruptions, lymphadenopathy, chest pain, and dyspnea. Certain drugs (e.g., antibiotics, anticancer agents, and anti-inflammatory medications) and infectious disorders (e.g., hepatitis B) may also cause serum sickness-like reaction.
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Definition (NCI_CTCAE)
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A disorder characterized by a delayed-type hypersensitivity reaction to foreign proteins derived from an animal serum. It occurs approximately six to twenty-one days following the administration of the foreign antigen. Symptoms include fever, arthralgias, myalgias, skin eruptions, lymphadenopathy, chest marked discomfort and dyspnea.
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Definition (MSH)
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Immune complex disease caused by the administration of foreign serum or serum proteins and characterized by fever, lymphadenopathy, arthralgia, and urticaria. When they are complexed to protein carriers, some drugs can also cause serum sickness when they act as haptens inducing antibody responses.
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Definition (CSP)
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immune complex disease caused by the administration of foreign serum or serum proteins and characterized by fever, lymphadenopathy, arthralgia, and urticaria; when they are complexed to protein carriers, some drugs can also cause serum sickness when they act as haptens inducing antibody responses.
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| Concepts |
Disease or Syndrome
(T047)
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| MSH |
D012713
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| ICD10 |
T80.6
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| SnomedCT |
72284000, 213324007, 213322006, 213323001, 213325008 |
| English |
Serum Sicknesses, Sickness, Serum, Sicknesses, Serum, SERUM SICKNESS, serum reaction (diagnosis), serum sickness (diagnosis), serum intoxication, serum rash, serum reaction, serum intoxication (diagnosis), serum rash (diagnosis), serum sickness, urticaria due to serum (diagnosis), protein sickness, urticaria due to serum, protein sickness (diagnosis), Serum urticaria, Serum Sickness [Disease/Finding], Serum Sickness, Serum sickness (disorder), Protein sickness, Serum sickness, Intoxication by serum, Serum rash, Serum reaction, Transfusion reaction due to serum protein reaction, Urticaria due to serum, Serum rash (disorder), Transfusion reaction due to serum protein reaction (disorder), Urticaria due to serum (disorder), intoxication; serum, protein; sickness, rash; serum, reaction; serum, serum; intoxication, serum; rash, serum; reaction, serum; urticaria, urticaria; serum, Transfusion reaction due to serum protein reaction, NOS |
| French |
MALADIE SERIQUE, Séroréaction, Maladie sérique, Maladie du sérum |
| Portuguese |
DOENCA DO SORO, Reacção sérica, Doença do soro, Doença do Soro |
| Spanish |
ENFERMEDAD DEL SUERO, Reacción del suero, rash del suero, sarpullido del suero, salpullido del suero, enfermedad del suero (trastorno), enfermedad del suero, erupción sérica, intoxicación por suero, rash sérico (trastorno), rash sérico, reacción a una transfusión por reacción de las proteínas del suero (trastorno), reacción a una transfusión por reacción de las proteínas del suero, reacción del suero, urticaria por suero (trastorno), urticaria por suero, urticaria secundaria al suero, Enfermedad del suero, Enfermedad del Suero |
| German |
SERUMKRANKHEIT, Serumreaktion, Serumkrankheit |
| Italian |
Malattia da siero, Reazione da siero |
| Dutch |
serumreactie, exantheem; serum, intoxicatie; serum, proteïne; aandoening, reactie; serum, serum; exantheem, serum; intoxicatie, serum; reactie, serum; urticaria, urticaria; serum, serumziekte, Serumziekte, Ziekte, serum- |
| Japanese |
血清病, 血清反応, ｹｯｾｲﾋﾞｮｳ, ｹｯｾｲﾊﾝﾉｳ |
| Swedish |
Serumsjuka
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| Czech |
sérová nemoc, Sérová reakce, Sérová nemoc |
| Finnish |
Seerumitauti
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| Russian |
SYVOROTOCHNAIA BOLEZN', СЫВОРОТОЧНАЯ БОЛЕЗНЬ |
| Polish |
Choroba posurowicza
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| Hungarian |
Szérumreakció, Szérumbetegség |
| Norwegian |
Serumsykdom, Serumsyke |
