II. Indications
III. Mechanism
- See Antihistamine
- H1 Receptor Antagonist
- Carbinoxamine Maleate is an Ethanolamine First Generation Antihistamine with high Anticholinergic activity
IV. Precautions
- Although FDA approved for children, FDA does not recommend routine Antihistamine use age <4 years
- Deaths have occurred in younger children related to Anticholinergic Toxicity
V. Dosing: Regular Release Formulation
- Adult: 4 to 8 mg orally three to four times daily
- Child age 2 to 3 years: 2 mg orally three to four times daily
- Child age 3 to 6 years: 2 to 4 mg orally three to four times daily
- Child age 2 to 3 years: 4 to 6 mg orally three to four times daily
VI. Adverse Effects
- See Antihistamine
- See Anticholinergic Toxicity
- Sedation
VII. Safety
- Pregnancy category C
- Avoid in Lactation
VIII. Resources
- Carbinoxamine (DailyMed)
IX. References
- Olson (2020) Clinical Pharmacology, Medmaster Miami, p. 146-7
- Hamilton (2020) Tarascon Pocket Pharmacopoeia
Images: Related links to external sites (from Bing)
Related Studies
| carbinoxamine (on 12/21/2022 at Medicaid.Gov Survey of pharmacy drug pricing) | ||
| CARBINOXAMINE MALEATE 4 MG TAB | Generic | $0.34 each |
| ryvent (on 9/9/2022 at Medicaid.Gov Survey of pharmacy drug pricing) | ||
| RYVENT 6 MG TABLET | $6.79 each | |
Ontology: carbinoxamine (C0054672)
| Concepts | Pharmacologic Substance (T121) , Organic Chemical (T109) |
| MSH | C004649 |
| SnomedCT | 372896001, 90882008 |
| LNC | LP18915-6, MTHU006864 |
| English | carbinoxamine, N,N-dimethyl-2-(p-chloro-alpha-(2-pyridyl)benzyloxy)ethylamine, carbinoxamine [Chemical/Ingredient], CARBINOXAMINE, Carbinoxamine, Carbinoxamine (product), Carbinoxamine (substance) |
| Spanish | carbinoxamina (producto), carbinoxamina (sustancia), carbinoxamina |
