II. Epidemiology
- Uncommon to rare
- Outbreaks
- Kew Garden Apartments in Queens, New York City (1946)
III. Pathophysiology
- Rickettsia Akari
- Organism in the spotted fever group
- Tiny Gram Negative Cocci
- Obligate intracellular Parasites
- Transmission
- Reservoir: Mice
- Mites (Liponyssoides sanguineus) feeds on mice and then transmits to humans via bite
IV. Findings
- Initial: Arthropod Bite (Mite bite)
- Next: Flu-like symptoms
- Next
- Diffuse, Generalized Rash with vesicular lesions
V. Differential Diagnosis
VI. Management
- Spontaneously resolves in 2-3 weeks without treatment
- Unlike other Rickettsial infections, disease is mild and no mortality in untreated cases
-
Antibiotics results in prompt resolution
- Doxycycline 100 mg orally twice daily for 7 days
- Alternatives
- Chloramphenicol 500 mg orally or IV four times daily for 7 days
- Azithromycin 10 mg/kg/day for 1 dose (for children age <8 years)
VII. Prevention
- Control of rodent population within home
VIII. Resources
- Rickettsialpox (Wikipedia)
IX. References
- Gladwin, Trattler and Mahan (2014) Clinical Microbiology, Medmaster, Fl, p. 117
- Krusell (2002) Emerg Infect Dis 8(7):727-8 +PMID: 12095443 [PubMed]
Images: Related links to external sites (from Bing)
Related Studies
| Concepts | Disease or Syndrome (T047) |
| MSH | D012288 |
| ICD9 | 083.2 |
| ICD10 | A79.1 |
| SnomedCT | 75096007 |
| English | Rickettsialpox, rickettsial pox, rickettsialpox, rickettsialpox (diagnosis), Rickettsia akari infection, Rickettsial pox, pox rickettsial, Rickettsialpox due to Rickettsia akari, Vesicular rickettsiosis, Kew Gardens spotted fever, Rickettsialpox (disorder), Kew Garden fever, Kew Garden; fever, Kew Garden; spotted fever, Rickettsia; akari, smallpox, Rickettsia; smallpox, fever; Kew Garden, rickettsiosis; vesicular, smallpox; due to Rickettsia akari, spotted fever; Kew Garden, vesicular; rickettsiosis |
| Italian | Rickettsial pox, Rickettsiosi vescicolare, Infezione da Rickettsia akari |
| Dutch | Rickettsia akari-infectie, Kew Garden; fever, Kew Garden; spotted fever, Rickettsia; akari, pokken, Rickettsia; pokken, fever; Kew Garden, pokken; door Rickettsia akari, rickettsiose; vesiculeus, spotted fever; Kew Garden, vesiculeus; rickettsiose, Rickettsiapokken door Rickettsia akari, rickettsia-pokken, Rickettsia-pokken |
| French | Infection à Rickettsia akari, Rickettsiose varicelliforme, Fièvre vésiculeuse, Rickettsialpox |
| German | Rickettsia akari-Infektion, Rickettsienpocken, Rickettsienpocken durch Rickettsia akari |
| Portuguese | Infecção por Rickettsia akari, Rickettsiose Vesicular, Riquetsiose variceliforme |
| Spanish | Infección por Rickettsia akari, Rickettsiosis vesicular, Rickettsiosis Pustulosa, rickettsiosis pustulosa (trastorno), rickettsiosis pustulosa por Rickettsia akari, rickettsiosis pustulosa, rickettsiosis vesicular, Rickettsiosis exantemática |
| Japanese | リケッチア・アカリ感染, リケッチア痘症, ﾘｹｯﾁｱﾄｳｼｮｳ, ﾘｹｯﾁｱｱｶﾘｶﾝｾﾝ |
| Czech | Ricketsiové neštovice, Infekce Rickettsia akari |
| Korean | 리켓치아 아카리에 의한 리켓치아성 두창 |
| Hungarian | Rickettsia akari fertőzés, Rickettsia himlő |
| Norwegian | Rickettsiakopper |
Ontology: Rickettsia akari (C0318313)
| Definition (MSH) | A species of gram-negative bacteria that causes rickettsialpox. The vector is a mouse mite and the reservoirs are mites and mice. |
| Concepts | Bacterium (T007) |
| MSH | D041141 |
| SnomedCT | 30769009 |
| English | Rickettsia akari, rickettsia akari, rickettsialpox, Dermacentroxenus murinus, Gamasoxenus muris, Rickettsia akari Huebner et al. 1946, Rickettsia akari (organism) |
| Swedish | Rickettsia akari |
| Czech | Rickettsia akari |
| Finnish | Rickettsia akari |
| Polish | Rickettsia akari |
| Norwegian | Rickettsia akari |
| Spanish | Rickettsia akari (organismo), Rickettsia akari |
| French | Rickettsia akari |
| German | Rickettsia akari |
| Italian | Rickettsia akari |
| Russian | RICKETTSIA AKARI |
| Dutch | Rickettsia akari |
| Portuguese | Rickettsia akari |
