II. Types
- Distal Sensory Polyneuropathy (most-common HIV-associated Neuropathy)
- Common complication at any stage of HIV Infection
- Varicella Zoster Virus (VZV) commonly involved
- Toxic Peripheral Neuropathy
- HIV Treatment with nRTI agents, especially older agents (e.g. DDI or Didanosine)
- Demyelinating Neuropathy
- Resembles Guillain-Barre
- Seen in early HIV
- Ascending sensorimotor Neuropathy with Incontinence or polyradiculopathy
- Cytomegalovirus (CMV) infection
- May involve the spinal cord segment
- May present with a painful extremity
- Cytomegalovirus (CMV) infection
III. Symptoms: Distal Sensory Polyneuropathy
- Distal lower extremity numbness, Paresthesias, or pain
IV. Signs: Distal Sensory Polyneuropathy
- Decreased ankle Deep Tendon Reflexes
- Decreased lower extremity Sensation (esp. sharp and vibratory Sensation)
V. Differential Diagnosis
VI. Management
- See Peripheral Neuropathy
-
General measures
- Eliminate Neurotoxins (e.g. older Antiretroviral agents)
- Control comorbidities (e.g. Diabetes Mellitus, Alcohol Abuse)
- Reduce HIV Viral Load
- Symptomatic management
VII. References
Images: Related links to external sites (from Bing)
Related Studies
| Concepts | Disease or Syndrome (T047) |
| Dutch | perifere neuropathie ten gevolge van HIV |
| French | Neuropathie périphérique liée au VIH |
| German | periphere Neuropathie bei HIV |
| Italian | Neuropatia periferica HIV-correlata |
| Portuguese | Neuropatia periférica ligada ao HIV |
| Spanish | Neuropatía periférica por VIH |
| Japanese | ＨＩＶ末梢性ニューロパチー, HIVﾏｯｼｮｳｾｲﾆｭｰﾛﾊﾟﾁｰ |
| Czech | Periferní neuropatie HIV |
| Hungarian | HIV peripheriás neuropathia |
| English | HIV peripheral neuropathy |
Ontology: HIV associated polyneuropathy (C3160946)
| Concepts | Disease or Syndrome (T047) |
| English | HIV associated polyneuropathy |
| Spanish | Polineuropatía asociada al VIH |
| Portuguese | Polineuropatia associada ao HIV |
| Italian | Polineuropatia associata a HIV |
| German | HIV-assoziierte Polyneuropathie |
| French | Polyneuropathie associée au VIH |
| Dutch | hiv-geassocieerde polyneuropathie |
| Czech | Polyneuropatie související s HIV |
| Japanese | ＨＩＶ関連多発ニューロパチー, HIVｶﾝﾚﾝﾀﾊﾂﾆｭｰﾛﾊﾟﾁｰ |
| Hungarian | HIV-el összefüggő polyneuropathia |
