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Definition (NCI_NCI-GLOSS)
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A nutrient in the vitamin B complex that the body needs in small amounts to function and stay healthy. Cyanocobalamin helps make red blood cells, DNA, RNA, energy, and tissues, and keeps nerve cells healthy. It is found in liver, meat, eggs, poultry, shellfish, milk, and milk products. Cyanocobalamin is water-soluble (can dissolve in water) and must be taken in every day. Not enough cyanocobalamin can cause certain types of anemia (a condition in which the number of red blood cells is below normal) and neurologic disorders. It is being studied with folate in the prevention and treatment of some types of cancer.
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Definition (NCI_CRCH)
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Cobalt-containing water soluble vitamin that is a coenzyme in the metabolism of fatty acids of odd-chain length and in methyl transfer. (DRI)
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Definition (NCI_NCI-GLOSS)
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A nutrient in the vitamin B complex that the body needs in small amounts to function and stay healthy. Vitamin B12 helps make red blood cells, DNA, RNA, energy, and tissues, and keeps nerve cells healthy. It is found in liver, meat, eggs, poultry, shellfish, milk, and milk products. Vitamin B12 is water-soluble (can dissolve in water) and must be taken in every day. Not enough vitamin B12 can cause certain types of anemia (a condition in which the number of red blood cells is below normal) and neurologic disorders. It is being studied with folate in the prevention and treatment of some types of cancer.
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Definition (NCI)
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A cobalt-containing coordination compound generated by intestinal microbes, and a natural water-soluble vitamin of the B-complex family that must combine with Intrinsic Factor for absorption by the intestine. Cyanocobalamin is necessary for hematopoiesis, neural metabolism, DNA and RNA production, and carbohydrate, fat, and protein metabolism. B12 improves iron functions in the metabolic cycle and assists folic acid in choline synthesis. B12 metabolism is interconnected with that of folic acid. Vitamin B12 deficiency causes pernicious anemia, megaloblastic anemia, and neurologic lesions.
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Definition (CSP)
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cyanocobalamin or cobalamin derivative with similar biological activity; a water soluble hematopoietic vitamin, absorbed in the intestine after combination with intrinsic factor.
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Definition (MSH)
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A cobalt-containing coordination compound produced by intestinal micro-organisms and found also in soil and water. Higher plants do not concentrate vitamin B 12 from the soil and so are a poor source of the substance as compared with animal tissues. INTRINSIC FACTOR is important for the assimilation of vitamin B 12.
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Definition (PDQ)
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An essential nutrient and natural water-soluble vitamin of the B-complex family that must combine with an intrinsic factor for absorption by the intestine, Vitamin B12 (cyanocobalamin) is necessary for hematopoiesis, neural metabolism, DNA and RNA production, and carbohydrate, fat, and protein metabolism. B12 improves iron functions in the metabolic cycle and assists folic acid in choline synthesis. B12 metabolism is interconnected with that of folic acid. Vitamin B12 deficiency causes pernicious anemia, megaloblastic anemia, and neurologic lesions. Check for "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=530928&idtype=1" active clinical trials or "http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=530928&idtype=1&closed=1" closed clinical trials using this agent. ("http://nciterms.nci.nih.gov:80/NCIBrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C939" NCI Thesaurus)
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| Concepts |
Pharmacologic Substance
(T121)
, Organic Chemical
(T109)
, Vitamin
(T127)
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| MSH |
D014805
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| SnomedCT |
81064004, 11611006, 30010009, 259664005, 327706007, 419382002 |
| LNC |
LP15262-6, LP31689-0, LP32549-5 |
| English |
B 12, Vitamin, B12, Vitamin, Cyanocobalamin, Vitamin B 12, Vitamin B12, vitamin B12, Vitamin B12 preparation, Vitamin B12 (substance) [Ambiguous], Vitamin B12 preparation (product), Vitamin B12 preparation (substance), Vitamin B<sub>12</sub> (substance) [Ambiguous], Vitamin B<sub>12</sub> preparation (product), Vitamin B<sub>12</sub> preparation (substance), Vitamin B<sub>12</sub> preparation, cyanocobalamin, Vitamin B-12, vitamin B12 compound, VITAMIN B A 12, B12 - Vitamin B12, B12 - Cyanocobalamin, cyanocobalamin (medication), vitamin B12 (medication), vitamins cyanocobalamin, Cobalamin, Cobalamin (1+), CYANOCOBALAMIN, Vitamin B 12 [Chemical/Ingredient], vitamin B 12, vit b12, b 12 vitamin, Vitamin B<sub>12</sub>, Vitamin B12 (substance), Vitamin B>12<, Vitamin B>12< (substance), Vitamin B<sub>12</sub> (substance), COBALAMIN, B12 - Cyanocobalamin prep, Cyanocobalamin preparation, Cyanocobalamin product, Vitamin B>12< preparation, Cyanocobalamin preparation (product), Vitamin B>12< preparation (product), Cyanocobalamin preparation (substance), Vitamin B>12< (substance) [Ambiguous], Vitamin B>12< preparation (substance), VIT B12, Vitamin-B12, B12 Vitamin, CYANOCOBALMIN, Cyanocobalamin (substance) |
| Spanish |
cianocobalamina, cianocobalamina (sustancia), vitamina B12 (concepto no activo), vitamina B<sub>12</sub> (concepto no activo), preparado de vitamina B<sub>12</sub> (sustancia), preparado de vitamina B12 (sustancia), preparado con vitamina B>12< (producto), preparado con vitamina B<sub>12</sub> (producto), vitamina B>12< (producto), vitamina B12, preparado con vitamina B12 (producto), vitamina B12 (producto), vitamina B>12<, cianocobalamina (producto), cobalamina, preparado con cianocobalamina (producto), vitamina B<sub>12</sub>, vitamina B<sub>12</sub> (producto), preparado con cianocobalamina, preparado con vitamina B<sub>12</sub>, preparado con vitamina B12, preparado con vitamina B>12<, vitamina B12 (sustancia), vitamina B<sub>12</sub> (sustancia), vitamina B>12< (sustancia), B12 - cianocobalamina, Vitamina B12, preparado de cianocobalamina (sustancia), preparado de vitamina B>12< (sustancia), vitamina B>12< (concepto no activo), Cianocobalamina, Vitamina B 12 |
| German |
Zyanocobalamin, Cyanokobalamin, Zyanokobalamin, VITAMIN B A 12, Cyanocobalamin, Vitamin B12 |
| Swedish |
Vitamin B12
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| Czech |
vitamin B 12
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| Finnish |
Syanokobalamiini
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| Italian |
Cianocobalamina, Vitamina B12 |
| Russian |
TSIANOKOBALAMIN, VITAMIN B12, KOBALAMIN, ВИТАМИН B12, КОБАЛАМИН, ЦИАНОКОБАЛАМИН |
| Japanese |
ビタミンB12, シアノコバラミン, コバラミン |
| Polish |
Cyjanokobalamina, Kobalamina, Witamina B12 |
| Norwegian |
Not Translated[Vitamin B 12]
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| Portuguese |
Vitamina B12, Cianocobalamina, Vitamina B 12 |
| French |
Cyanocobalamine, Vitamine B12 |
