II. Definitions
- Acute Aortic Occlusion (AAO)
- Rare, life threatening, sudden Occlusion of the aorta, either by thrombosis or embolism
III. Epidemiology
- Rare
- Infrarenal Aortic Occlusion is most common
IV. Risk Factors
- Thrombosis
- Atherosclerosis
- Low flow states (e.g. major surgery)
- Hypercoagulable state
- Tobacco Abuse
- Diabetes Mellitus
- Blunt Abdominal Trauma
- May result in injury to aortic intima layer, precipitating thrombosis
- Abdominal Aortic Aneurysm
- Male gender
- Prior aortic reconstruction surgery (e.g. endovascular aortic aneurysm repair)
- Embolism
- Valvular heart disease
- Female gender
- Atrial Fibrillation
V. Findings
- Background
- Presentating signs relate to level of obstruction
- Thrombotic Occlusions may be more subtle on presentation due to collateral circulation
- Torso
- Abdominal Pain or tenderness
- Back pain
- Bilateral Acute Limb Ischemia
- Acute pain or Paresthesias
- Leg paralysis or weakness
- Decreased lower extremity Deep Tendon Reflexes
- Leg mottling, pallor or coldness
- Decreased or absent peripheral pulses
- Renal Involvement (suprarenal Occlusion)
VI. Causes
- Thrombosis (60 to 70% of cases)
- Most commonly infrarenal
- Occlusion of aortic reconstruction such as aorta graft or stent (10-20%)
- Saddle embolism (10 to 20%)
- Historically most common, but modern Anticoagulants have reduced Incidence of embolism
- Typically occurs as a large saddle embolism to the aortic bifurcation (to the iliac arteries)
VII. Differential Diagnosis
VIII. Imaging
-
Bedside Ultrasound
- Performed as part of initial exam
- FAST Scan
-
Abdominal Aorta Ultrasound
- Observe for echogenic material within aorta, without color flow
- Common femoral artery Ultrasound
- CT Angiography of Aorta (Chest AbdomenPelvis CTA)
- First-line study
IX. Management
-
General Measures
- Opioid Analgesics
- Anticoagulation with weight-based Heparin
- ABC Management
- Emergent vascular surgery Consultation for operative intervention
- Thromboembolectomy
- Axillary-Bifemoral Bypass
- Aortic-Biilliac/Bifemoral Bypass
- Other therapeutic options
- Consider Thrombolysis (esp. distal lesions)
X. Complications
- Mortality: 34 to 52%
- Highest mortality with suprarenal Occlusion
- Acute Renal Failure: 50%
- Limb Amputation: 7 to 31%
- Fasciotomy: 20 to 33%
- Mesenteric Ischemia 10 o 14%
- Acute Myocardial Ischemia: 14%
XI. References
- Adibi (2020) Acute Aortic Occlusion, EMdocs, accessed 1/1/2022
- Crawford (2014) J Vasc Surg 59:1044-50 [PubMed]
- Grip (2019) Circulation 139:292-4 [PubMed]