II. Epidemiology

  1. Onset within first two years of life

III. See Also

IV. Definition

  1. Severe Lymphedema onset at birth or as infant
  2. Milroy's Disease is a famial subtype

V. Signs

  1. Lower Extremity Edema
    1. Right leg more often affected
    2. Bilateral involvement in 25% of cases
  2. Involves foot dorsum up to knee

VI. Associated Conditions

  1. Swelling of external genitalia
  2. Intestinal lymphangiectasia, Protein-losing Enteropathy
  3. Cystic Hygroma
  4. Pulmonary lymphangiectasia

VII. References

  1. Sabiston (1997) Surgery, Saunders, p.1574-5
  2. Rockson (2001) Am J Med 110:288-95 [PubMed]

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