II. Epidemiology

  1. Abdominal Pain in Children accounts for 9-10% of emergency department and primary care visits
  2. Incidence of acute surgical presentations of Abdominal Pain
    1. Emergency Department: 10-30% of acute Abdominal Pain in Children requires surgery
    2. Overall: 2% requires surgery

III. Types

  1. Acute Abdominal Pain
    1. Characteristics
      1. Less than 4-6 weeks (subacute less than 12 weeks)
      2. Single episode, self limited and treatable
      3. Episodic localized pain, sharp, stabbing
    2. Common Benign Causes (see below for more serious causes)
      1. Upper Respiratory Infection, Pharyngitis, Otitis Media or sinsuitis (23%)
      2. Gastroenteritis (15%)
      3. Constipation (9%)
      4. Urinary Tract Infection (8%)
  2. Chronic Abdominal Pain
    1. Characteristics
      1. Three episodes over 3 months
      2. Continuous, dull, vague and diffuse Abdominal Pain
      3. Recurrent, Associated with debilitation
    2. Common Benign Causes (see below for more serious causes)
      1. Constipation
      2. Lactose intollerance
      3. Mittelschmerz
      4. Psychogenic (See Recurrent Abdominal Pain Syndrome)
        1. Secondary Gain
        2. Sexual abuse
        3. School Phobia

IV. Causes

  1. See Pediatric Abdominal Pain Causes
  2. See Differential Diagnosis below

V. History: Red Flags

  1. Acute
    1. Bilious Vomiting
    2. Fever
      1. Especially if onset after the Abdominal Pain onset (higher risk of peritonitis)
    3. Localized pain away from midline
    4. Bloody Diarrhea
  2. Chronic
    1. Altered bowel habits
    2. Growth disturbance
    3. Nocturnal episodes
    4. Radiation of pain
    5. Incontinence urine or stool
    6. Systemic symptoms

VI. History: Abdominal Pain

  1. See Abdominal Pain Evaluation
  2. Timing
    1. Onset of Abdominal Pain
    2. Frequency, Duration and time of day
    3. Which days of the week
  3. Characteristics
    1. Location and radiation of Abdominal Pain
    2. Intensity and character
  4. Key Associated Symptoms
    1. Fever
    2. Anorexia
    3. Decreased Activity
    4. Change in stool consistency or frequency (Diarrhea or Constipation)
    5. Vomiting
      1. Vomiting (before or after pain?)
      2. Bilious Vomiting suggests obstruction
    6. Bloody stool?
      1. Peptic Ulcer
      2. Bowel ischemia
    7. Genitourinary Symptoms
      1. Dysuria, urgency, frequency or hematura
      2. Gynecologic symptoms (e.g. Vaginal Discharge, Vaginal Bleeding)
      3. Testicular or Scrotal Pain
      4. Inguinal Masses or Hernias
  5. Exacerbating and relieving features
    1. Relationship to activity and school
    2. Attempted therapies
    3. Relieved with movement (esp. poorly localized pain)
      1. Visceral pain (e.g. Volvulus)
    4. Worse with movement (esp. sharp and localized)
      1. Abdominal Wall Pain
  6. Hydration status
    1. Level of alertness (lethargy vs alert and attentive)
    2. Tolerating oral intake without Emesis? How much intake?
    3. Adequate Urine Output (>3/day under age 1, and >2/day over age 1)
  7. Food associations
    1. Milk or cheese
    2. Spicy food
    3. Caffeinated soda, tea
  8. Other associated symptoms
    1. Fatigue
    2. Syncope
    3. Headache or CNS symptoms
    4. Upper Respiratory Infection, cough or Pharyngitis
      1. Consider Streptococcal Pharyngitis
      2. Consider Pneumonia

VII. History: Past Medical History

  1. General history
    1. Surgical history (esp. abdominal surgeries)
    2. Medications
    3. Major illnesses or hospitalizations
    4. Growth and development
  2. Sickle Cell Disease
    1. Splenic Sequestration
    2. Vaso-Occlusive Pain Crisis
    3. Gall Bladder disorder
    4. Intrahepatic cholestasis
  3. Immunosuppression
    1. Immunosuppressed patients with subtle findings despite severe underling abdominal abnormalities
    2. Neutropenia
      1. Neutropenic Enterocolitis (Typhlitis) presents as Right Lower Quadrant Abdominal Pain
  4. Anorexia or other condition causing rapid weight loss
    1. Superior Mesenteric Artery Syndrome may present with severe Abdominal Pain with Vomiting
  5. Cerebral Palsy
    1. Constipation (most common)
    2. Sigmoid Volvulus

VIII. History: Family History

IX. History: Social History (chronic Abdominal Pain in teens)

  1. See HEEADSSS Mnemonic (Adolescent History)
  2. Home
    1. Death, divorce, serious illness, care providers, siblings
  3. Education
  4. Activities
  5. Drug Use
  6. Suicidal Ideation
  7. Sexual activity

X. Exam

  1. Perform in comfortable, non-threatening environment
  2. Appearance
    1. See Inconsolable Crying in Infants
    2. Moaning in discomfort
    3. Motionless or lethargy (peritonitis)
    4. Writhing (e.g. Renal Colic)
  3. Vital Signs
    1. Fever
    2. Tachycardia
    3. Weight (compare with prior)
  4. Comprehensive exam
    1. Heart, lung and general exam should be performed before abdominal exam
    2. Evaluate for referred pain
      1. Throat exam
        1. Streptococcal Pharyngitis
        2. Mononucleosis
      2. Lung Exam
        1. Pneumonia
      3. Hip Exam
        1. Toxic Synovitis
        2. Septic hip
  5. Abdominal exam
    1. See Abdominal Pain Exam
    2. Palpation
      1. Consider asking parents to push on Abdomen (with examiners hands on top)
      2. Use stethoscope to apply pressure
      3. Examine the most painful area last (as with all patients)
    3. Rebound Abdominal Pain
      1. Avoid removing hand rapidly (loses patient trust)
      2. May test rebound as "Jump on and off table" or bump the side of the table
    4. Other red flag findings
      1. See Abdominal Pain Exam for specific signs (e.g. rosving sign, Psoas Sign)
      2. Abdominal Distention
      3. Absent or decreased bowel sounds
      4. Other peritonitis signs (e.g. abdominal rigidity)
  6. Genitourinary exam
    1. Perform in all cases of Pediatric Abdominal Pain
      1. However, in suspected sexual abuse, exam should be deferred to trained examiner (e.g. forensic nurse)
    2. Girls
      1. Ovarian Torsion
      2. Ectopic Pregnancy (adolescent)
      3. Pelvic Inflammatory Disease (adolescent)
    3. Boys
      1. Testicular Torsion
      2. Undescended Testicle
      3. Inguinal Hernia
      4. Epididymitis or Orchitis
  7. Rectal Exam
    1. Consider

XI. Labs

  1. Screening
    1. Complete Blood Count
    2. Comprehensive Metabolic Panel (including Liver Function Tests)
    3. Serum Lipase
    4. C-Reactive Protein (or ESR)
    5. Urinalysis
      1. Clean catch urine or catheterized urine
    6. Post-pubertal girls
      1. Urine Pregnancy Test (Urine HCG)
      2. Consider Gonorrhea PCR and Chlamydia PCR
  2. Consider additional testing
    1. Streptococcal Rapid Antigen Test
      1. Epigastric Pain often accompanies Streptococcal Pharyngitis in children
    2. Monospot
      1. Mononucleosis may also present with Abdominal Pain
    3. Stool Stool NAT or cultures (bloody Diarrhea or Dysentery)
      1. Escherichia coli
      2. Campylobacter
      3. Salmonella
      4. Shigella
      5. Yersinia
    4. Parasite evaluation (Chronic Diarrhea)
      1. Ova and Parasites (Stool NAT often includes Giardia, Cryptosporidium and other Parasites)
      2. GiardiaAntigen
      3. Cryptosporidium (Immunocompromised Children)
    5. Helicobacter Pylori titer (Peptic Ulcer Disease)
    6. Transaminase increase
      1. Hepatitis Serologies (Hepatitis A, and if risks, Hepatitis B and Hepatitis C)
    7. Lead Level

XII. Imaging

  1. Flat and Upright abdominal XRay or KUB (not routinely used)
    1. Typically low yield, but low radiation exposure
    2. Ingested Foreign Body
    3. Small Bowel Obstruction
    4. Abdominal free air
    5. Constipation (non-specific)
    6. Appendicolith may be seen in Appendicitis (low yield)
  2. Abdominal Ultrasound
    1. Preferred first-line study for Pediatric Abdominal Pain imaging
    2. Appendicitis or intussception
    3. Cholecystitis
    4. Hydronephrosis or Renal Mass
    5. Testicular Torsion
    6. Ovarian Torsion, Ectopic Pregnancy or Tuboovarian Abscess
    7. Pyloric Stenosis (Projectile Vomiting in young infants)
  3. Upper GI with Small Bowel follow through
    1. Evaluate for Volvulus
  4. Other studies
    1. Abdominal CT (avoid if possible due to significant radiation exposure)
      1. See CT-associated Radiation Exposure
    2. Ultrafast 3T MRI (3 Tesla MRI)
      1. Focused MRI can complete Appendicitis imaging in 6 minutes
      2. Johnson (2012) AJR Am J Roentgenol 198( 6): 1424-30 [PubMed]
    3. Skeletal Survey (assess physical abuse)
    4. Upper endoscopy (EGD)
    5. Colonoscopy
      1. Inflammatory Bowel Disease

XIII. Differential Diagnosis: Acute Pain

  1. See Pediatric Abdominal Pain Causes
  2. Intussusception
    1. Most common cause of acute Intestinal Obstruction in ages 3-12 months old
    2. Ultrasound is preferred imaging modality (high Test Sensitivity and Specificity)
  3. Volvulus
    1. Presents with Bilious Emesis and Abdominal Pain in newborns, infants and young children
    2. Congenital malrotation of the bowel allows for Volvulus
    3. Upper GI series is preferred imaging modality
  4. Appendicitis
    1. Classic signs and symptoms of Appendicitis warrant surgical evaluation without imaging
    2. Ultrasound is typically performed as first-line study in unclear cases
    3. Surgical Consultation and serial examinations should be considered when Ultrasound is non-diagnostic
    4. Also consider Meckel Diverticulum
  5. Urinary Tract Infection
    1. Pyelonephritis
  6. Gynecologic causes
    1. Ovarian Torsion
    2. Ovarian Cyst
    3. Ectopic Pregnancy
    4. Pelvic Inflammatory Disease
  7. Males
    1. Testicular Torsion
    2. Inguinal Hernia
    3. Epididymitis or Orchitis
  8. Abdominal mass
    1. See Abdominal Mass in Children
    2. See Abdominal Mass in Newborns
  9. Trauma
    1. See Pediatric Abdominal Trauma
    2. Nonaccidental Trauma
  10. Non-abdominal causes
    1. Streptococcal Pharyngitis
    2. Pneumonia
    3. Abdominal Migraine
    4. Diabetic Ketoacidosis (common Type 1 Diabetes new presentation)
  11. Biliary Tract (growing importance due to Childhood Obesity)
    1. Cholelithiasis and Cholecystitis
    2. Acute Pancreatitis

XIV. Management: Acute Abdominal Pain

  1. See Acute Abdominal Pain
  2. See Acute Pelvic Pain
  3. See Functional Abdominal Pain in Children (Recurrent Abdominal Pain Syndrome)
  4. Initiate fluid Resuscitation early
  5. Do not delay Analgesics in Acute Abdominal Pain
    1. Use Opioid Analgesics where appropriate (as you would for adult patients with Abdominal Pain)
  6. Obtain early surgical Consultation when acute red flag findings are present
    1. Bilious Vomiting
    2. Bloody Diarrhea
    3. Fever
    4. Concerning abdominal exam findings (absent bowel sounds, Rebound Tenderness, rigidity or guarding)
  7. Constipation is a diagnosis of exclusion
    1. Consider all serious Abdominal Pain causes first (and exclude based on a careful history and exam)
    2. Normal labs (including CBC, CRP) do not exclude Appendicitis or intussception
  8. Serial re-examination in 12-16 hours in uncertain cases
    1. Diagnosis changes in 30% of cases
    2. Toorenvliet (2010) World J Surg 34(3):480-6 [PubMed]

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Related Studies

Ontology: Abdominal Pain (C0000737)

Definition (MSHCZE) Pocit nevolnosti, obtíží nebo bolesti v břišní oblasti; obvykle při funkčních poruchách, tkáňových poraněních nebo nemocech.
Definition (MEDLINEPLUS)

Your abdomen extends from below your chest to your groin. Some people call it the stomach, but your abdomen contains many other important organs. Pain in the abdomen can come from any one of them. The pain may start somewhere else, such as your chest. Severe pain doesn't always mean a serious problem. Nor does mild pain mean a problem is not serious.

Call your healthcare provider if mild pain lasts a week or more or if you have pain with other symptoms. Get medical help immediately if

  • You have abdominal pain that is sudden and sharp
  • You also have pain in your chest, neck or shoulder
  • You're vomiting blood or have blood in your stool
  • Your abdomen is stiff, hard and tender to touch
  • You can't move your bowels, especially if you're also vomiting
Definition (NCI_CTCAE) A disorder characterized by a sensation of marked discomfort in the abdominal region.
Definition (NCI) Painful sensation in the abdominal region.
Definition (MSH) Sensation of discomfort, distress, or agony in the abdominal region; generally associated with functional disorders, tissue injuries, or diseases.
Concepts Sign or Symptom (T184)
MSH D015746 , D003085
ICD9 789.00, 789.0
ICD10 R10.9
SnomedCT 207205003, 207230000, 158498003, 158512003, 139313005, 21522001
LNC MTHU013636, LA15468-4
English Abdominal Pains, Pains, Abdominal, Abdominal pain NOS, Abdominal Pain, [D]Abdominal pain (context-dependent category), [D]Abdominal pain NOS (context-dependent category), Abdo pain, Pain abdo, Abd. pain, [D]Abdominal pain, [D]Abdominal pain NOS, abdominal pain (symptom), abdominal pain, Pain abdominal, Gut pain, Abdmnal pain unspcf site, Unspecified abdominal pain, Abdominal Pain [Disease/Finding], Pain;abdominal, gut pain, abdomen pain, abdominal pains, Bellyache, Pain, Abdominal, Abdomen pain, [D]Abdominal pain (situation), [D]Abdominal pain NOS (situation), ABDOMINAL PAIN, PAIN, ABDOMINAL, Abdominal pain, AP - Abdominal pain, Abdominal pain (finding), abdominal; pain, abdominalgia, pain; abdominal, Abdominal pain, unspecified site
French DOULEUR ABDOMINALE, Douleur abdominale SAI, Douleur intestinale, Douleur abdo, Douleur abdo., Douleur abd., Colique, Douleur abdominale, Douleur de l'abdomen
Portuguese DOR ABDOMINAL, Dor abdominal NE, Dor intestinal, Câimbras Abdominais, Cólicas, Câimbra Abdominal, Cãibra Abdominal, Dor abdominal, Cólica, Dor Abdominal
Dutch darmpijn, buikpijn NAO, pijn abdominaal, abdominaal; pijn, pijn; abdominaal, abdominale pijn, Buikpijn, Pijn, buik-
German Schmerz abdominal, Bauchschmerz, abd. Schmerz, Abdominalschmerzen NNB, Schmerz abdo, abdo. Schmerz, ABDOMEN SCHMERZHAFT, Abdominalschmerz, Abdominalschmerzen, Bauchschmerzen, Kolik
Italian Dolore intestinale, Dolore addominale NAS, Dolore colico, Colica, Dolore addominale
Spanish Dolor de barriga, Dolor abdominal NEOM, [D]dolor abdominal, SAI (categoría dependiente del contexto), [D]dolor abdominal (categoría dependiente del contexto), ABDOMEN, DOLOR, [D]dolor abdominal (situación), [D]dolor abdominal, SAI (situación), [D]dolor abdominal, [D]dolor abdominal, SAI, dolor abdominal (hallazgo), dolor abdominal, Dolor abdominal, Dolor Abdominal
Japanese 腸管痛, 腹痛NOS, 腹痛, フクツウ, チョウカンツウ, フクツウNOS, 疝痛, 腹部痙攣, 仙痛, 腹部けいれん
Swedish Buksmärta
Czech kolika, Břišní bolest NOS, Střevní bolest, Bolest břicha, bolesti břicha, břicho - bolest
Finnish Koliikki, Vatsakipu
Russian BRIUSHNAIA POLOST', BOLI, ABDOMINAL'NAIA BOL', KOLIKA, ABDOMINAL'NYI SPAZM, АБДОМИНАЛЬНАЯ БОЛЬ, АБДОМИНАЛЬНЫЙ СПАЗМ, БРЮШНАЯ ПОЛОСТЬ, БОЛИ
Croatian ABDOMINALNA BOL
Polish Ból brzucha
Hungarian Hasi fájdalom, Abdominalis fájdalom k.m.n., Bél fájdalom, Abdominalis fájdalom, Hasfájdalom
Norwegian Kolikksmerter, Magesmerter, Kolikk, Abdominalsmerter, Magesmerte