II. Background
- Modern CT Scanners capture isotropic voxels (3 dimensional pixels)
- Voxels allows for software recompositing of imaging into any slice plane (e.g. coronal slices)
- Does not require specific instructions beyond overall imaging technique (e.g. IV contrast)
- Jaffe (2007) Radiology 242:175-81 [PubMed]
III. Indications: Acute Abdominal Pain (Oral water and IV Contrast unless otherwise noted)
- Appendicitis
- Diverticulitis
- Bowel Obstruction
- Acute Pancreatitis
- Ureterolithiasis or Nephrolithiasis (no contrast)
- Abdominal Aortic Aneurysm (IV contrast only)
- Mesenteric Ischemia
- Crohn's Disease (CT enterography)
- Abdominal Trauma (IV contrast only)
- Intraabdominal abscess (with Oral Contrast in addition to IV contrast)
IV. Technique: Oral Contrast
- Most Abdominal CT protocols require oral water only (no Oral Contrast)
- Patients with increased abdominal fat require less contrast
- Evaluation for Appendicitis or Diverticulitis does NOT require Oral Contrast
- Low Attenuation Contrast (air, water) is usually preferable to high attenuation Oral Contrast (e.g. barium, diatrizoate)
- High attenuation contrast may obscure malignancy and intestinal Hemorrhage
- Air alone is an excellent contrast due to low attenuation (-1000 Hounsfield Units)
- Allows for pneumoperitoneum (perforation) detection
- Oral water (400-600 ml) immediately prior to CT helps identify gastric lesions
- References
- Broder (2018) Crit Dec Emerg Med 32(6): 12-3
- High Attentuation Oral Contrast (Gastrografin/Gastroview, Omnipaque, Readi-Cat/Barium) Indications
- Patient indications for Oral Contrast
- Lean patient (e.g. BMI <19-20 kg/m2)
- Age <18 years old
- Condition indications for Oral Contrast
- Bowel Fistula
- Bowel perforation or Peptic Ulcer perforation
- Intraabdominal Abscess
- Patient indications for Oral Contrast
- References
V. Technique: Intravenous Contrast
- Types
- Non-Contrast CT
- Single Phase CT
- Imaging at a single time period after contrast injection
- Multi-Phase CT
- Imaging at more than one time period after contrast injection
- Generally avoided if possible due to greater radiation exposure
- Used in Blunt Abdominal Trauma to highlight vascular, parenchymal and urinary tract injuries
- Non-Contrast CT (or precontrast CT)
- Clearly delineates intraabdominal anatomy and identifies abnormal lesions
- Preferred imaging when Ureteral Stone is suspected
- Ureteral Stones are also seen well on IV contrast imaging (but avoid Oral Contrast)
- Non-Contrast CT also has high sensitivity for other conditions in which contrast is often used
- Low sensitivity for lesions requiring CT contrast (high False Negative Rate)
- Vascular abnormalities (e.g. dissection, vessel obstruction, active Hemorrhage with extravasation)
- Solid organ infarction
- Biliary obstruction (surrounding liver parenchyma enhances with IV contrast)
- Solid organ mass (IV contrast highlights mass borders and invasion)
- With IV contrast, masses may be bright if hypervascular or enhance less if hypovascular
- Early Arterial Phase (15 to 25 sec after contrast injection)
- Evaluates for arterial pathology (e.g. Aortic Dissection, Mesenteric Ischemia, vascular injury)
- Late Arterial Phase (30 to 40 sec after contrast injection)
- Evaluates for vascular injury or dissection
- Also evaluates for hypervascular solid organ lesions (e.g. Hepatocellular Carcinoma)
- Pancreatic Phase (40 to 50 sec after contrast injection)
- Evaluates pancreatic lesions
- Portal Venous Phase (60 to 90 sec after contrast injection, Standard CT Timing)
- Standard CT imaging timing is the default protocol that identifies most pathology
- Primary imaging phase used in undifferentiated Abdominal Pain and solid organ Trauma
- Nephrogenic Phase or delayed phase (85 to 120 sec after contrast injection, e.g. CT Urogram)
- Excretory Phase (5 to 10 minutes after contrast injection)
- Evaluates for urinary tract injury or leak
VI. Adverse Effects: Children
- Sold-tumor risk from CT radiation exposure in children
- See CT-associated Radiation Exposure
- Girls: 1 new cancer per 300-390 CT Abdomen and Pelvis
- Boys: 1 new cancer per 670-760 CT Abdomen and Pelvis
- Miglioretti (2013) JAMA Pediatr 167(8): 700-7 [PubMed]
VII. References
- Ashoo, Orman and Hollander in Herbert (2015) EM:Rap 15(6): 17
- Broder (2022) Crit Dec Emerg Med 36(5): 20-1
- Broder (2024) Crit Dec Emerg Med 38(8): 22-3