Enteric Pathogens Nucleic Acid Test Panels

Aka: Enteric Pathogens Nucleic Acid Test Panels, Stool NAT, Fecal PCR Test

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II. Background

  1. Replaces Stool Culture
  2. Other stool Antigen tests that may be ordered individually, but are not included on standard panels
    1. Clostridium difficile Toxin (often ordered at the same time as the Enteric Panel)
    2. Giardia lambliaAntigen
    3. CryptosporidiumAntigen

III. Indications

  1. Dysentery (Bloody Diarrhea, Fever, Abdominal Pain, Tenesmus)
  2. More than 6 stools daily
  3. More than 1 week of symptoms
  4. Hospital admission for Dehydration
  5. Age over 65 years
  6. Immunocompromised status
  7. High risk patient
    1. Age >65 years old
    2. Infant <12 months
    3. Pregnancy
    4. Immunocompromised state
    5. Men who have Sex with Men

IV. Lab: Organisms Identified

  1. Varies by manufacturer
  2. Campylobacter
  3. Salmonella
  4. Shigella
  5. Vibrio
  6. Yersinia
  7. Norovirus
  8. Rotavirus
  9. Shiga-Toxin

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